Search Results - "STRASBURGER, C. J"

Oral Octreotide Absorption in Human Subjects: Comparable Pharmacokinetics to Parenteral Octreotide and Effective Growth Hormone Suppression by Tuvia, S, Atsmon, J, Teichman, S. L, Katz, S, Salama, P, Pelled, D, Landau, I, Karmeli, I, Bidlingmaier, M, Strasburger, C. J, Kleinberg, D. L, Melmed, S, Mamluk, R

“…Context: Oral administration of a novel octreotide formulation enabled its absorption to the systemic circulation, exhibiting blood concentrations comparable…”
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A consensus on the diagnosis and treatment of acromegaly complications by Melmed, S., Casanueva, F. F., Klibanski, A., Bronstein, M. D., Chanson, P., Lamberts, S. W., Strasburger, C. J., Wass, J. A. H., Giustina, A.

“…In March 2011, the Acromegaly Consensus Group met to revise and update the guidelines on the diagnosis and treatment of acromegaly complications. The meeting…”
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Treatment of acromegaly with the GH receptor antagonist pegvisomant in clinical practice: Safety and efficacy evaluation from the German Pegvisomant Observational Study by Schreiber, I, Buchfelder, M, Droste, M, Forssmann, K, Mann, K, Saller, B, Strasburger, C J

“…Objective: The GH receptor antagonist pegvisomant is a highly effective new treatment option in acromegaly. The German Pegvisomant Observational Study (GPOS)…”
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Evaluation of health-related quality of life in patients with Cushing's syndrome with a new questionnaire by Webb, S M, Badia, X, Barahona, M J, Colao, A, Strasburger, C J, Tabarin, A, van Aken, M O, Pivonello, R, Stalla, G, Lamberts, S W J, Glusman, J E

“…Chronic exposure to hypercortisolism has significant impact on patient's health and health-related quality of life (HRQoL), as demonstrated with generic…”
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Intraoperative indocyanine green videoangiography for identification of pituitary adenomas using a microscopic transsphenoidal approach by Sandow, N., Klene, W., Elbelt, U., Strasburger, C. J., Vajkoczy, P.

“…Purpose Initial successful surgical treatment of pituitary adenomas is crucial to reach long-term remission. Indocyanine green (ICG) videoangiography (VA) is…”
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Efficacy and acceptability of lanreotide Autogel® 120 mg at different dose intervals in patients with acromegaly previously treated with octreotide LAR by Schopohl, J, Strasburger, C J, Caird, D, Badenhoop, K, Beuschlein, F, Droste, M, Plöckinger, U, Petersenn, S

“…To assess the efficacy of different dosing intervals of lanreotide, Somatuline Autogel® (Lan-ATG) 120 mg in patients with acromegaly, previously treated with…”
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The German ACROSTUDY: past and present by Buchfelder, M, Schlaffer, S, Droste, M, Mann, K, Saller, B, Brübach, K, Stalla, G K, Strasburger, C J

“…Pivotal studies have demonstrated that pharmacotherapy with pegvisomant (Somavert) is a highly effective treatment for acromegaly. Since clinical experience…”
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Pituitary tumor size in acromegaly during pegvisomant treatment: experience from MR re-evaluations of the German Pegvisomant Observational Study by Buchfelder, M, Weigel, D, Droste, M, Mann, K, Saller, B, Brübach, K, Stalla, G K, Bidlingmaier, M, Strasburger, C J

“…In treatment-resistant patients with acromegaly, pharmacotherapy with pegvisomant (Somavert) is a highly effective option. However, safety concerns have been…”
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Postoperative Evaluation of Patients with Acromegaly: Clinical Significance and Timing of Oral Glucose Tolerance Testing and Measurement of (Free) Insulin-Like Growth Factor I, Acid-Labile Subunit, and Growth Hormone-Binding Protein Levels by Feelders, R. A., Bidlingmaier, M., Strasburger, C. J., Janssen, J. A. M. J. L., Uitterlinden, P., Hofland, L. J., Lamberts, S. W. J., van der Lely, A. J., de Herder, W. W.

“…Context: It is not exactly known when patients with acromegaly should be evaluated for cure after transsphenoidal adenomectomy (TA). Objective: The objective…”
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Generation of Human Soluble Leptin Receptor by Proteolytic Cleavage of Membrane-Anchored Receptors by Maamra, M, Bidlingmaier, M, Postel-Vinay, M.-C, Wu, Z, Strasburger, C. J, Ross, R. J. M

“…The leptin receptor (ObR) exists in multiple isoforms. In rodents, a soluble isoform is generated by alternative splicing; but in humans, there is no mRNA…”
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Impact of Experimental Blockade of Peripheral Growth Hormone (GH) Receptors on the Kinetics of Endogenous and Exogenous GH Removal in Healthy Women and Men by Veldhuis, J. D., Bidlingmaier, M., Anderson, S. M., Evans, W. S., Wu, Z., Strasburger, C. J.

“…Organs that respond to and metabolize GH are enriched in cognate high-affinity receptors. However, whether isologous receptors mediate the de facto access of…”
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High-Dose Leptin Activates Human Leukocytes Via Receptor Expression on Monocytes by Zarkesh-Esfahani, Hamid, Pockley, Graham, Metcalfe, Russell A, Bidlingmaier, Martin, Wu, Zida, Ajami, Abolghasem, Weetman, Anthony P, Strasburger, Christian J, Ross, Richard J. M

“…Leptin is capable of modulating the immune response. Proinflammatory cytokines induce leptin production, and we now demonstrate that leptin can directly…”
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Systemic Regulation of Distraction Osteogenesis: A Cascade of Biochemical Factors by Weiss, S., Baumgart, R., Jochum, M., Strasburger, C. J., Bidlingmaier, M.

“…This study investigates the systemic biochemical regulation of fracture healing in distraction osteogenesis compared with rigid osteotomy in a prospective in…”
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Diagnosis and treatment of acromegaly complications by GIUSTINA, A, CASANUEVA, F. F, LAMBERTS, S. W. J, LOMBARDI, G, SHEPPARD, M, STRASBURGER, C. J, VANCE, M. L, WASS, J. A. H, MELMED, S, CAVAGNINI, F, CHANSON, P, CLEMMONS, D, FROHMAN, L. A, GAILLARD, R, HO, K, JAQUET, P, KLEINBERG, D. L

“…The Pituitary Society in conjunction with the European Neuroendocrine Association held a consensus workshop to develop guidelines for diagnosis and treatment…”
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Synthesis of a cortisol-biotin conjugate and evaluation as a tracer in an immunoassay for salivary cortisol measurement by Dressendörfer, R A, Kirschbaum, C, Rohde, W, Stahl, F, Strasburger, C J

“…Cortisol 3-(o-carboxymethyl)oxime (C3-CMO) and a commercially available biotin-hydrazide derivative were used to synthesize a C3-CMO-biotin conjugate. C3-CMO…”
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Detection of doping with human growth hormone by Wu, Zida, Bidlingmaier, Martin, Dall, Rolf, Strasburger, Christian J

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Retraction Note: Influence of hypobaric hypoxia on leptin levels in men by Tschöp, M, Strasburger, C J, Töpfer, M, Hautmann, H, Riepl, R, Fischer, R, Hartmann, G, Morrison, K, Appenzeller, M, Hildebrandt, W, Biollaz, J, Bärtsch, P

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Lowering total plasma insulin-like growth factor I concentrations by way of a novel, potent, and selective growth hormone (GH) receptor antagonist, pegvisomant (B2036-peg), augments the amplitude of GH secretory bursts and elevates basal/nonpulsatile GH release in healthy women and men by VELDHUIS, J. D, BIDLINGMAIER, M, ANDERSON, S. M, WU, Z, STRASBURGER, C. J

“…The present clinical study implements a novel interventional strategy of short-term profound and selective blockade of GH receptors to reduce plasma…”
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Salivary cortisol levels throughout childhood and adolescence : relation with age, pubertal stage, and weight by KIESS, W, MEIDERT, A, DRESSENDÖRFER, R. A, SCHRIEVER, K, KESSLER, U, KÖNIG, A, SCHWARZ, H. P, STRASBURGER, C. J

“…The measurement of cortisol in saliva has become a reliable tool for both the scientist and the clinician for studying adrenal cortical function in the adult…”
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Elevated transaminases during medical treatment of acromegaly: a review of the German pegvisomant surveillance experience and a report of a patient with histologically proven chronic mild active hepatitis by Biering, H, Saller, B, Bauditz, J, Pirlich, M, Rudolph, B, Johne, A, Buchfelder, M, Mann, K, Droste, M, Schreiber, I, Lochs, H, Strasburger, C J

“…Objective: The new GH receptor antagonist pegvisomant is the most effective medical therapy to normalize IGF-I levels in patients with acromegaly. Based on…”
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