Search Results - "STRAHLENDORF, J. C"

A transient voltage-dependent outward potassium current in mammalian cerebellar Purkinje cells by Wang, Y, Strahlendorf, J C, Strahlendorf, H K

“…Utilizing the single electrode voltage clamp technique applied to rat Purkinje cells (PCs), we have recorded a transient outward voltage-dependent potassium…”
Get more information

AMPA receptor-mediated alterations of intracellular calcium homeostasis in rat cerebellar Purkinje cells in vitro : Correlates to dark cell degeneration by STRAHLENDORF, J. C, BRANDON, T, MILES, R, STRAHLENDORF, H. K

“…In the rat cerebellar slice preparation in vitro, excessive DL-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA)-receptor activation elicits a…”
Get full text

Diazoxide and cyclothiazide convert AMPA-induced dark cell degeneration of Purkinje cells to edematous damage in the cerebellar slice by Strahlendorf, Jean C., Acosta, Steve, Strahlendorf, Howard K.

“…Using the in vitro cerebellar slice preparation from young rats (8–12 days old), AMPA produced in addition to dark cell degeneration (DCD), an edematous type…”
Get full text

Modulatory role of serotonin on GABA-elicited inhibition of cerebellar Purkinje cells by Strahlendorf, J C, Lee, M, Strahlendorf, H K

“…The present study was designed to directly examine the postsynaptic actions of serotonin on GABA-mediated inhibition of cerebellar Purkinje cells. The findings…”
Get more information

Serotonin alters an inwardly rectifying current (Ih) in rat cerebellar Purkinje cells under voltage clamp by Li, S J, Wang, Y, Strahlendorf, H K, Strahlendorf, J C

“…The effects of serotonin (5-HT) on the hyperpolarization-activated sodium-potassium inward current (H-current: Ih) were examined in cerebellar Purkinje cells…”
Get more information

Effects of serotonin on cerebellar Purkinje cells are dependent on the baseline firing rate by STRAHLENDORF, J. C, LEE, M, STRAHLENDORF, H. K

“…Serotonin applied iontophoretically to cerebellar Purkinje cells elicited one of three effects: inhibition (62% of the cells), biphasic response (27%), and…”
Get full text

Serotonin reduces a voltage-dependent transient outward potassium current and enhances excitability of cerebellar Purkinje cells by Wang, Y, Strahlendorf, J C, Strahlendorf, H K

“…Utilizing current-clamp and single electrode voltage-clamp techniques we have studied the actions of serotonin (5-HT) on a transient outward voltage-dependent…”
Get more information

Modulatory action of serotonin on glutamate-induced excitation of cerebellar Purkinje cells by Lee, M, Strahlendorf, J C, Strahlendorf, H K

“…The effects of serotonin (5-hydroxytryptamine, 5-HT) on glutamate-induced excitation of Purkinje cells were examined. Pulsatile iontophoretic applications of…”
Get more information

Enhancement of cerebellar Purkinje cell complex discharge activity by microiontophoretic serotonin by STRAHLENDORF, J. C, STRAHLENDORF, H. K, LEE, M

“…The major finding of the present study is that iontophoretically applied serotonin increased markedly (average 94.0%) the number of complex discharges within…”
Get full text

Extracellular magnesium concentration alters Purkinje cell responsiveness to serotonin and analogues by Darrow, E, Strahlendorf, J C, Strahlendorf, H K

“…Binding studies have shown that divalent cations increase the affinity of 5-hydroxytryptamine 1A (5-HT1A) receptors for ligands. The present study compared the…”
Get more information

Serotonergic interactions with rat cerebellar Purkinje cells by Strahlendorf, J C, Hubbard, G D

“…Recent immunocytochemical and histofluorescent studies have established the vastness of the serotonergic fibers arising from the raphe complex and projecting…”
Get more information

Differential effects of N-methyl-D-aspartic acid and L-homocysteic acid on cerebellar Purkinje neurons by Lee, M, Strahlendorf, H K, Strahlendorf, J C

“…The effects of N-methyl-D-aspartic acid (NMDA) and L-homocysteic acid (LH) were measured on cerebellar Purkinje neurons. In urethane-anesthetized rats,…”
Get more information

Choline blocks AMPA-induced dark cell degeneration of Purkinje neurons: potential role of the alpha 7 nicotinic receptor by Strahlendorf, J C, Acosta, S, Miles, R, Strahlendorf, H K

“…The objective of the present study was to assess the contribution of sodium influx to development of dark cell degeneration (DCD) in Purkinje neurons (PNs)…”
Get full text

Pentobarbital augments serotonin-mediated inhibition of cerebellar Purkinje cells by Strahlendorf, J C, Lee, M, Netzeband, J G, Strahlendorf, H K

“…The ability of pentobarbital to modify the direct effects of iontophoretically ejected serotonin on the firing rates of cerebellar Purkinje cells was examined…”
Get more information

Ionic contributions to the oscillatory firing activity of rat Purkinje cells in vitro by Chang, W, Strahlendorf, J C, Strahlendorf, H K

“…Oscillatory firing activity in cerebellar Purkinje cells (PCs) can be maintained by intrinsic ionic conductances in the apparent absence of excitatory and…”
Get more information

Enhanced sensitivity of cerebellar Purkinje cells to iontophoretically-applied serotonin in thiamine deficiency by Lee, R S, Strahlendorf, H K, Strahlendorf, J C

“…Electrophysiological aspects of thiamine depletion in the rat induced by dietary deficiency are described. Behavioral changes as well as qualitative and…”
Get more information

Effects of serotonin and the 5-HT2/1C receptor agonist DOI on neurons of the cerebellar dentate/interpositus nuclei: possible involvement of a GABAergic interneuron by Cumming-Hood, P A, Strahlendorf, H K, Strahlendorf, J C

“…The present study was designed to examine the effects of iontophoretically applied serotonin (5-HT) on neurons of the cerebellar dentate/interpositus nuclei in…”
Get more information

Inhibition of periaqueductal gray neurons by the arcuate nucleus: partial mediation by an endorphin pathway by Strahlendorf, J C, Strahlendorf, H K, Barnes, C D

Get full text

Response of cerebellar Purkinje cells to serotonin and the 5-HT1A agonists 8-OH-DPAT and ipsapirone in vitro by Darrow, E J, Strahlendorf, H K, Strahlendorf, J C

“…These studies were undertaken in an attempt to classify the receptor subtypes mediating the inhibitory effects of serotonin (5-HT) on cerebellar Purkinje cells…”
Get more information

Serotonin modulates muscimol- and baclofen-elicited inhibition of cerebellar Purkinje cells by Strahlendorf, J C, Lee, M H, Strahlendorf, H K

“…The present study was designed to test whether serotonin (5-HT) preferentially affects the GABAA or GABAB receptor subtypes in the cerebellum using muscimol…”
Get more information