Search Results - "STRADER, April D"

Estradiol-Dependent Decrease in the Orexigenic Potency of Ghrelin in Female Rats by CLEGG, Deborah J, BROWN, Lynda M, ZIGMAN, Jeffrey M, KEMP, Christopher J, STRADER, April D, BENOIT, Stephen C, WOODS, Stephen C, MANGIARACINA, Michela, GEARY, Nori

“…Estradiol-Dependent Decrease in the Orexigenic Potency of Ghrelin in Female Rats Deborah J. Clegg 1 , Lynda M. Brown 2 , Jeffrey M. Zigman 3 , Christopher J…”
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Ileal Interposition Surgery Improves Glucose and Lipid Metabolism and Delays Diabetes Onset in the UCD-T2DM Rat by Cummings, Bethany P, Strader, April D, Stanhope, Kimber L, Graham, James L, Lee, Jennifer, Raybould, Helen E, Baskin, Denis G, Havel, Peter J

“…Background & Aims Bariatric surgery has been shown to reverse type 2 diabetes; however, mechanisms by which this occurs remain undefined. Ileal interposition…”
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Ileal Interposition Improves Glucose Tolerance in Low Dose Streptozotocin-treated Diabetic and Euglycemic Rats by Strader, April D., Clausen, Trine Ryberg, Goodin, Sean Z., Wendt, Donna

“…Background The surgical treatment for obesity promotes massive weight loss and early improvement in co-morbid conditions such as type-2 diabetes. Because…”
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Weight loss through ileal transposition is accompanied by increased ileal hormone secretion and synthesis in rats by Strader, April D, Vahl, Torsten P, Jandacek, Ronald J, Woods, Stephen C, D'Alessio, David A, Seeley, Randy J

“…Bariatric surgeries, such as gastric bypass, result in dramatic and sustained weight loss that is usually attributed to a combination of gastric volume…”
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Sexually dimorphic responses to fat loss after caloric restriction or surgical lipectomy by Shi, Haifei, Strader, April D, Woods, Stephen C, Seeley, Randy J

“…White adipose tissue is the principal site for lipid accumulation. Males and females maintain distinctive white adipose tissue distribution patterns…”
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Alterations in Oxygen Consumption, Respiratory Quotient, and Heat Production in Long-Lived GHRKO and Ames Dwarf Mice, and Short-Lived bGH Transgenic Mice by Westbrook, Reyhan, Bonkowski, Michael S., Strader, April D., Bartke, Andrzej

“…Growth hormone (GH) signaling influences longevity in mice, with decreased GH signaling associated with longer life span and increased GH signaling with…”
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Gastrointestinal hormones and food intake by Strader, April D., Woods, Stephen C.

“…Despite dramatic fluctuations in calorie intake, animals maintain a very stable body weight. The reason is that energy intake and expenditure are precisely…”
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The role of the melanocortin system and the melanocortin-4 receptor in ring dove ( Streptopelia risoria) feeding behavior by Strader, April D., Schiöth, Helgi B., Buntin, John D.

“…The melanocortin-4 receptor (MC4-R) is an important mediator of the effects of two melanocortin system ligands, alpha melanocyte stimulating hormone (α-MSH)…”
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The effects of the melanocortin agonist (MT-II) on subcutaneous and visceral adipose tissue in rodents by Strader, April D, Shi, Haifei, Ogawa, Ryuichi, Seeley, Randy J, Reizes, Ofer

“…The melanocortin system is a critical pathway in the regulation of energy balance. In this study, we analyzed the peripheral effects of the synthetic…”
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Metabolic alterations due to caloric restriction and every other day feeding in normal and growth hormone receptor knockout mice by Westbrook, Reyhan, Bonkowski, Michael S, Arum, Oge, Strader, April D, Bartke, Andrzej

“…Mutations causing decreased somatotrophic signaling are known to increase insulin sensitivity and extend life span in mammals. Caloric restriction and every…”
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Adaptation of Intestinal and Bile Acid Physiology Accompany the Metabolic Benefits Following Ileal Interposition in the Rat by Zhao, Ping, Wendt, Donna, Goodin, Sean Z., Ravichandran, Shwetha, Chouinard, Tara E., Strader, April D.

“…Purpose Ileal interposition recapitulates many of the metabolic improvements similar to Roux-en-Y gastric bypass. We aimed to determine whether the metabolic…”
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Ileal transposition provides insight into the effectiveness of gastric bypass surgery by Strader, April D.

“…Despite dramatically increased research efforts to discover cures for the rising health issue of obesity, bariatric (obesity) surgery remains the most…”
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(+)-Z -Bisdehydrodoisynolic Acid Enhances Basal Metabolism and Fatty Acid Oxidation in Female Obese Zucker Rats by Ajuwon, Kolapo M., Banz, William J., Davis, Jeremy E., Meyers, Cal Y., Hou, Yuqing, Strader, April D.

“…We have previously reported that the synthetic estrogen, (+)-Z-bisdehydrodoisynolic Acid [(+)-Z-BDDA], attenuated weight gain and cardiovascular risk in obese…”
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The effect of fat removal on glucose tolerance is depot specific in male and female mice by Shi, Haifei, Strader, April D, Woods, Stephen C, Seeley, Randy J

“…Energy is stored predominately as lipid in white adipose tissue (WAT) in distinct anatomical locations, with each site exerting different effects on key…”
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Sexually different actions of leptin in proopiomelanocortin neurons to regulate glucose homeostasis by Shi, Haifei, Strader, April D, Sorrell, Joyce E, Chambers, James B, Woods, Stephen C, Seeley, Randy J

“…Leptin regulates energy balance and glucose homeostasis, at least in part, via activation of receptors in the arcuate nucleus of the hypothalamus located in…”
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Mice lacking the syndecan-3 gene are resistant to diet-induced obesity by Strader, April D, Reizes, Ofer, Woods, Stephen C, Benoit, Stephen C, Seeley, Randy J

“…The accurate matching of caloric intake to caloric expenditure involves a complex system of peripheral signals and numerous CNS neurotransmitter systems…”
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Effect of gonadectomy on AgRP-induced weight gain in rats by Goodin, Sean Z, Kiechler, Alicia R, Keichler, Alicia R, Smith, Marissa, Wendt, Donna, Strader, April D

“…Agouti-related peptide (AgRP), the endogenous antagonist to the melanocortin 3 and 4 receptors, elicits robust hyperphagia and weight gain in rodents when…”
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Sensitivity to the anorectic effects of leptin is retained in rats maintained on a ketogenic diet despite increased adiposity by Kinzig, Kimberly P, Honors, Mary Ann, Hargrave, Sara L, Davenport, Brandon M, Strader, April D, Wendt, Donna

“…Rats maintained on a ketogenic diet (KD; 80% fat, 15% protein, 5% carbohydrate) have increased adiposity and leptin as compared to chow-fed controls (CH; 16%…”
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Ileal interposition attenuates the satiety responses evoked by cholecystokinin-8 and -33 by Metcalf, Shannon A., Washington, Martha C., Brown, Thelma A.L., Williams, Carol S., Strader, April D., Sayegh, Ayman I.

“…► Ileal interposition (II) may alter the satiety responses evoked by CCK. ► We measured food intake in response to CCK-8 and -33 in these rats. ► Both peptides…”
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PL-303: Improved glucose tolerance, insulin and GLP-1 secretion in a high-fat fed streptozotocin-treated rat model with ileal interposition by Zhao, Ping, Ravichandran, Shwetha, MS, Strader, April D., PhD

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