Search Results - "STOWERS, Anthony W"

In Vitro Studies with Recombinant Plasmodium falciparum Apical Membrane Antigen 1 (AMA1): Production and Activity of an AMA1 Vaccine and Generation of a Multiallelic Response by KENNEDY, Michael C, JIN WANG, YANLING ZHANG, MILES, Aaron P, CHITSAZ, Farideh, SAUL, Allan, LONG, Carole A, MILLER, Louis H, STOWERS, Anthony W

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Vaccination of Monkeys with Recombinant Plasmodium falciparum Apical Membrane Antigen 1 Confers Protection against Blood-Stage Malaria by STOWERS, Anthony W, KENNEDY, Michael C, KEEGAN, Brian P, SAUL, Allan, LONG, Carole A, MILLER, Louis H

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The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms by Saxena, Ajay K, Garboczi, David N, Singh, Kavita, Su, Hua-Poo, Klein, Michael M, Stowers, Anthony W, Saul, Allan J, Long, Carole A

“…P25 and P28 proteins are essential for Plasmodium parasites to infect mosquitoes and are leading candidates for a transmission-blocking malaria vaccine. The…”
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Antibodies to Malaria Vaccine Candidates Pvs25 and Pvs28 Completely Block the Ability of Plasmodium vivax To Infect Mosquitoes by HISAEDA, Hajime, STOWERS, Anthony W, TSUBOI, Takafumi, COLLINS, William E, SATTABONGKOT, Jetsumon S, SUWANABUN, Natavadee, TORII, Motomi, KASLOW, David C

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Biochemical and Immunological Characterization of Bacterially Expressed and Refolded Plasmodium falciparum 42-Kilodalton C-Terminal Merozoite Surface Protein 1 by SINGH, Sanjay, KENNEDY, Michael C, LONG, Carole A, SAUL, Allan J, MILLER, Louis H, STOWERS, Anthony W

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Expression of malaria transmission-blocking vaccine antigen Pfs25 in Pichia pastoris for use in human clinical trials by Zou, Lanling, Miles, Aaron P, Wang, Jin, Stowers, Anthony W

“…In previously published studies, Saccharomyces cerevisiae recombinant protein expression systems have been employed to express the malaria parasite antigen…”
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CpG Oligodeoxynucleotide and Montanide ISA 51 Adjuvant Combination Enhanced the Protective Efficacy of a Subunit Malaria Vaccine by KUMAR, Sanjai, JONES, Trevor R, OAKLEY, Miranda S, HONG ZHENG, KUPPUSAMY, Shanmuga P, TAYE, Alem, KRIEG, Arthur M, STOWERS, Anthony W, KASLOW, David C, HOFFMAN, Stephen L

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A Recombinant Vaccine Expressed in the Milk of Transgenic Mice Protects Aotus Monkeys from a Lethal Challenge with Plasmodium falciparum by Stowers, Anthony W., Chen, Li-how, Zhang, Yanling, Kennedy, Michael C., Zou, Lanling, Lambert, Lynn, Rice, Timothy J., Kaslow, David C., Saul, Allan, Long, Carole A., Meade, Harry, Miller, Louis H.

“…Two strains of transgenic mice have been generated that secrete into their milk a malaria vaccine candidate, the 42-kDa C-terminal portion of Plasmodium…”
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Merozoite Surface Protein 3 and Protection against Malaria in Aotus nancymai Monkeys by Hisaeda, Hajime, Saul, Allan, Reece, Joshua J., Kennedy, Michael C., Long, Carole A., Miller, Louis H., Stowers, Anthony W.

“…A blood-stage vaccine based on Plasmodium falciparum merozoite surface protein 3 (MSP3) was tested for efficacy in a primate model. Aotus nancymai monkeys were…”
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Blocking of transmission to mosquitoes by antibody to Plasmodium vivax malaria vaccine candidates Pvs25 and Pvs28 despite antigenic polymorphism in field isolates by Sattabongkot, Jetsumon, Tsuboi, Takafumi, Hisaeda, Hajime, Tachibana, Mayumi, Suwanabun, Nantavadee, Rungruang, Thanaporn, Cao, Ya-Ming, Stowers, Anthony W, Sirichaisinthop, Jeeraphat, Coleman, Russell E, Torii, Motomi

“…We have previously demonstrated that mouse antisera against yeast-produced recombinant forms of the ookinete surface proteins of Plasmodium vivax (Pvs25 and…”
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Structure of the C-terminal Domains of Merozoite Surface Protein-1 from Plasmodium knowlesi Reveals a Novel Histidine Binding Site by Garman, Scott C, Simcoke, William N, Stowers, Anthony W, Garboczi, David N

“…The protozoan parasite Plasmodium causes malaria, with hundreds of millions of cases recorded annually. Protection against malaria infection can be conferred…”
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Immunization with a Combination of Merozoite Surface Proteins 4/5 and 1 Enhances Protection against Lethal Challenge with Plasmodium yoelii by KEDZIERSKI, Lukasz, BLACK, Casilda G, GOSCHNICK, Matthew W, STOWERS, Anthony W, COPPEL, Ross L

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Improved Immunogenicity and Efficacy of the Recombinant 19-Kilodalton Merozoite Surface Protein 1 by the Addition of Oligodeoxynucleotide and Aluminum Hydroxide Gel in a Murine Malaria Vaccine Model by NEAR, Karen A, STOWERS, Anthony W, JANKOVIC, Dragana, KASLOW, David C

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Effect of CpG Oligodeoxynucleotides on the Immunogenicity of Pfs25, a Plasmodium falciparum Transmission-Blocking Vaccine Antigen by COBAN, Cevayir, ISHII, Ken J, STOWERS, Anthony W, KEISTER, David B, KLINMAN, Dennis M, KUMAR, Nirbhay

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Large-Scale Purification and Characterization of Malaria Vaccine Candidate Antigen Pvs25H for Use in Clinical Trials by Miles, Aaron P., Zhang, Yanling, Saul, Allan, Stowers, Anthony W.

“…The budding yeast Saccharomyces cerevisiae has been used to express the recombinant protein Pvs25H, currently the only candidate transmission-blocking vaccine…”
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Montanide ® ISA 720 vaccines: quality control of emulsions, stability of formulated antigens, and comparative immunogenicity of vaccine formulations by Miles, Aaron P., McClellan, Holly A., Rausch, Kelly M., Zhu, Daming, Whitmore, Michael D., Singh, Sanjay, Martin, Laura B., Wu, Yimin, Giersing, Birgitte K., Stowers, Anthony W., Long, Carole A., Saul, Allan

“…Montanide ® ISA 720 is an experimental adjuvant, formulated as water-in-oil emulsions, that induces high antibody titers in several animal species. It has been…”
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Efficacy of two alternate vaccines based on Plasmodium falciparum merozoite surface protein 1 in an Aotus challenge trial by STOWERS, Anthony W, CIOCE, Vittoria, SHIMP, Richard L, LAWSON, Mark, HUI, George, MURATOVA, Olga, KASLOW, David C, ROBINSON, T. Robin, LONG, Carole A, MILLER, Louis H

“…In an attempt to produce a more defined, clinical-grade version of a vaccine based on Plasmodium falciparum merozoite surface protein 1 (MSP1), we evaluated…”
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Phase 1 study of two merozoite surface protein 1 (MSP1(42)) vaccines for Plasmodium falciparum malaria by Malkin, Elissa, Long, Carole A, Stowers, Anthony W, Zou, Lanling, Singh, Sanjay, MacDonald, Nicholas J, Narum, David L, Miles, Aaron P, Orcutt, Andrew C, Muratova, Olga, Moretz, Samuel E, Zhou, Hong, Diouf, Ababacar, Fay, Michael, Tierney, Eveline, Leese, Philip, Mahanty, Siddhartha, Miller, Louis H, Saul, Allan, Martin, Laura B

“…To assess the safety and immunogenicity of two vaccines, MSP1(42)-FVO/Alhydrogel and MSP1(42)-3D7/Alhydrogel, targeting blood-stage Plasmodium falciparum…”
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Are trials in New World monkeys on the critical path for blood-stage malaria vaccine development? by Stowers, Anthony W., Miller, Louis H.

“…The development of malaria blood-stage vaccines is gathering momentum: there are several new funding initiatives, one multiantigen formulation is currently…”
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A region of Plasmodium falciparum antigen Pfs25 that is the target of highly potent transmission-blocking antibodies by STOWERS, Anthony W, KEISTER, David B, MURATOVA, Olga, KASLOW, David C

“…Each of the four epidermal growth factor (EGF)-like domains of the Plasmodium falciparum sexual-stage antigen Pfs25 has been individually expressed as a…”
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