Search Results - "STOWELL, K. M"

Comparison of pathogenicity prediction tools on missense variants in RYR1 and CACNA1S associated with malignant hyperthermia by Schiemann, A.H., Stowell, K.M.

“…Malignant hyperthermia (MH) is a pharmacogenetic disorder that has been linked to the skeletal muscle calcium release channel (RYR1) and the α1S subunit of the…”
Get full text

Administration of anaesthetic triggering agents to patients tested malignant hyperthermia normal and their relatives in New Zealand: An update by Frei, D., Stowell, K. M., Langton, E. E., McRedmond, L., Pollock, N. A., Bulger, T. F.

“…Testing for malignant hyperthermia in New Zealand involves two tests-in vitro contracture testing of excised lateral quadriceps muscle and DNA analysis. In…”
Get full text

Safety of exposure of malignant hyperthermia non-susceptible patients and their relatives to anaesthetic triggering agents by POLLOCK, N, LANGTON, E. E, STOWELL, K. M, BULGER, T. F

“…As the reliability of malignant hyperthermia normal in vitro contracture test results has been questioned, this study set out to determine the reliability of…”
Get full text

Malignant hyperthermia in infancy and identification of novel RYR1 mutation by Chamley, D, Pollock, N A, Stowell, K M, Brown, R L

“…Malignant hyperthermia (MH) has been reported as non-existent in children less than 1 yr old, although several unconfirmed reports have been published. A case…”
Get full text

Neospora caninum: Quantification of DNA in the blood of naturally infected aborted and pregnant cows using real-time PCR by Okeoma, C.M., Stowell, K.M., Williamson, N.B., Pomroy, W.E.

“…This study quantified Neospora caninum DNA in the blood and brain of pregnant and aborted heifers by monitoring PCR product formation in real-time using SYBR…”
Get full text

Assessing the pathogenicity of RYR1 variants in malignant hyperthermia by Merritt, A., Booms, P., Shaw, M.-A., Miller, D.M., Daly, C., Bilmen, J.G., Stowell, K.M., Allen, P.D., Steele, D.S., Hopkins, P.M.

“…Missense variants in the ryanodine receptor 1 gene (RYR1) are associated with malignant hyperthermia but only a minority of these have met the criteria for use…”
Get full text

The use of PCR to detect Neospora caninum DNA in the blood of naturally infected cows by Okeoma, C.M, Williamson, N.B, Pomroy, W.E, Stowell, K.M, Gillespie, L

“…Twelve 2-year old heifers in their fifth month of gestation when pregnancy tested were used in this study. Six heifers aborted at approximately 4 months of…”
Get full text

A novel ryanodine receptor mutation and genotype-phenotype correlation in a large malignant hyperthermia New Zealand Maori pedigree by BROWN, R. L, POLLOCK, A. N, COUCHMAN, K. G, HODGES, M, HUTCHINSON, D. O, WAAKA, R, LYNCH, P, MCCARTHY, T. V, STOWELL, K. M

“…Malignant hyperthermia (MH) is a pharmacogenetic disorder that predisposes to a sometimes fatal hypermetabolic reaction to halogenated anaesthetics. MH is…”
Get full text

Sequence capture and massively parallel sequencing to detect mutations associated with malignant hyperthermia by Schiemann, A.H., Dürholt, E.M., Pollock, N., Stowell, K.M.

“…Malignant hyperthermia (MH) is a potentially fatal pharmacogenetic disorder in which intracellular calcium homeostasis in the skeletal muscle of susceptible…”
Get full text

Suspected Malignant Hyperthermia reactions in New Zealand by POLLOCK, A. N, LANGTON, E. E, COUCHMAN, K, STOWELL, K. M, WADDINGTON, M

“…Early clinical signs, triggering agents, time to onset of reaction, mortality and methods of treatment were identified in 123 suspected malignant hyperthermia…”
Get full text

Safe duration of postoperative monitoring for malignant hyperthermia patients administered non-triggering anaesthesia: an update by Barnes, C, Stowell, K M, Bulger, T, Langton, E, Pollock, N

“…The postoperative care of malignant hyperthermia (MH) patients is subject to international variation, with a paucity of data in the literature to guide…”
Get full text

Evidence of Malignant Hyperthermia in Patients Administered Triggering Agents before Malignant Hyperthermia Susceptibility Identified: Missed Opportunities Prior to Diagnosis by Chan, T. Y., Bulger, T. F., Stowell, K. M., Gillies, R. L., Langton, E. E., Street, N. E., Pollock, N. A.

“…Malignant hyperthermia (MH) is a hypermetabolic disorder of skeletal muscle triggered almost exclusively by potent inhalational agents and suxamethonium. Signs…”
Get full text

Isolation and molecular characterisation of Neospora caninum in cattle in New Zealand by Okeoma, CM, Williamson, NB, Pomroy, WE, Stowell, KM, Gillespie, LM

“…AIM: To isolate Neospora caninum from the brains of naturally infected cattle and use molecular techniques to characterise the isolates. METHODS: Neospora…”
Get full text

Recognition patterns of Neospora caninum tachyzoite antigens by bovine IgG at different IFAT titres by Okeoma, C. M., Williamson, N. B., Pomroy, W. E., Stowell, K. M.

“…SUMMARY This study describes qualitative and quantitative antibody response in cows naturally infected with Neospora caninum. The study was carried out with…”
Get full text

Recovery from Hemophilia B. Leyden: An Androgen-Responsive Element in the Factor IX Promoter by Crossley, Merlin, Ludwig, Michael, Stowell, Kathryn M., De Vos, Piet, Olek, Klaus, Brownlee, George G.

“…One form of the inherited, X-linked, bleeding disorder, hemophilia B, resolves after puberty. Mutations at -20 and -26 in the clotting factor IX promoter…”
Get full text

Studies of the N-terminal half of human lactoferrin produced from the cloned cDNA demonstrate that interlobe interactions modulate iron release by DAY, C. L, STOWELL, K. M, BAKER, E. N, TWEEDIE, J. W

“…The factors influencing iron binding and release by lactoferrin have been addressed by comparison of the native full length molecule (Lf) with the N-terminal…”
Get full text

Expression of cloned human lactoferrin in baby-hamster kidney cells by STOWELL, K. M, RADO, T. A, FUNK, W. D, TWEEDIE, J. W

“…Human lactoferrin was expressed from a cloned cDNA introduced into mammalian cells in tissue culture. Total RNA was extracted from human bone marrow, and…”
Get full text

DNA analysis and malignant hyperthermia susceptibility by Stowell, K M, Pollock, N

Get full text

Haemophilia B Liverpool: a new British family with mild haemophilia B associated with a -6 G to A mutation in the factor IX promoter by Stowell, K M, Figueiredo, M S, Brownlee, G G, Jones, P, Bolton-Maggs, P H

“…We report a Lancashire family with mild haemophilia B associated with a -6 G to A mutation in the factor IX promoter. This mutation has been reported…”
Get more information

The assessment of viability in isolated rat hepatocytes by Page, R A, Stowell, K M, Hardman, M J, Kitson, K E

“…Isolated rat hepatocytes are used in many metabolic studies, but the viability of these cell preparations is often not adequately established. The present…”
Get more information