Search Results - "STOVE, Christophe"
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Is the hematocrit still an issue in quantitative dried blood spot analysis?
Published in Journal of pharmaceutical and biomedical analysis (30-01-2019)“…•Hematocrit issues still prevent full acceptance of dried blood spot analysis.•Many attempts to overcome this hematocrit bias have been proposed.•Whole spot…”
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Identification of psychedelic new psychoactive substances (NPS) showing biased agonism at the 5-HT2AR through simultaneous use of β-arrestin 2 and miniGαq bioassays
Published in Biochemical pharmacology (01-12-2020)“…[Display omitted] Psychedelic new psychoactive substances (NPS), compounds exerting their main pharmacological effects through the activation of the serotonin…”
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Evaluation of the Capitainer‑B Microfluidic Device as a New Hematocrit-Independent Alternative for Dried Blood Spot Collection
Published in Analytical chemistry (Washington) (06-11-2018)“…The hematocrit-bias still remains one of the most discussed issues when it comes to dried blood spot (DBS) analysis. Therefore, many attempts to cope with this…”
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Volumetric absorptive microsampling as an alternative tool for therapeutic drug monitoring of first-generation anti-epileptic drugs
Published in Analytical and bioanalytical chemistry (01-03-2018)“…Dosage adjustment of anti-epileptic drugs by therapeutic drug monitoring (TDM) is very useful, especially for the first-generation anti-epileptic drugs (AEDs)…”
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In vitro assays for the functional characterization of (psychedelic) substances at the serotonin receptor 5‐HT2AR
Published in Journal of neurochemistry (01-07-2022)“…Serotonergic psychedelics are substances that induce alterations in mood, perception, and thought, and have the activation of serotonin (5‐HT) 2A receptors…”
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Fully automated therapeutic drug monitoring of anti-epileptic drugs making use of dried blood spots
Published in Journal of Chromatography A (13-09-2019)“…•Development and validation of a fully automated dried blood spot-based method for quantification of anti-epileptic drugs.•Optimization of the extraction…”
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Fully Automated Dried Blood Spot Extraction coupled to Liquid Chromatography-tandem Mass Spectrometry for Therapeutic Drug Monitoring of Immunosuppressants
Published in Journal of Chromatography A (13-09-2021)“…•Validation of a quantitative fully automated DBS-based method for immunosuppressants using the DBS-MS 500 and a reference method in whole…”
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Insights into biased signaling at cannabinoid receptors: synthetic cannabinoid receptor agonists
Published in Biochemical pharmacology (01-11-2019)“…[Display omitted] Cannabinoid receptors type 1 (CB1) and type 2 (CB2) are promising targets for a number of diseases, including obesity, neuropathic pain, and…”
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Increasing Confidence in a Phosphatidylethanol 16:0/18:1 Cutoff at 20 ng/mL to Support Abstinence or Minor Intake of Alcohol
Published in Clinical chemistry (Baltimore, Md.) (01-09-2023)Get full text
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Dried blood microsampling-assisted therapeutic drug monitoring of immunosuppressants: An overview
Published in Journal of Chromatography A (25-01-2023)“…•State-of-the-art of immunosuppressants analysis in (volumetric) dried blood samples.•Critical discussion of challenges related to quantification of…”
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Activity-Based Detection of Consumption of Synthetic Cannabinoids in Authentic Urine Samples Using a Stable Cannabinoid Reporter System
Published in Analytical chemistry (Washington) (05-09-2017)“…Synthetic cannabinoids (SCs) continue to be the largest group of new psychoactive substances (NPS) monitored by the European Monitoring Center of Drugs and…”
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Alternative Sampling Strategies in Therapeutic Drug Monitoring: Microsampling Growing Toward Maturity
Published in Therapeutic drug monitoring (01-06-2021)Get full text
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Detection and Activity Profiling of Synthetic Cannabinoids and Their Metabolites with a Newly Developed Bioassay
Published in Analytical chemistry (Washington) (06-12-2016)“…Synthetic cannabinoids (SCs) are the largest group of compounds currently monitored in Europe by the EU Early Warning System on new psychoactive substances…”
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Volumetric absorptive microsampling as a suitable tool to monitor tyrosine kinase inhibitors
Published in Journal of pharmaceutical and biomedical analysis (05-01-2022)“…•TDM of TKIs offers potential in guiding personalized cancer treatment.•LC-MS/MS method developed for the quantification of eight TKIs in VAMS samples.•Matrix…”
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In vitro structure–activity relationship determination of 30 psychedelic new psychoactive substances by means of β-arrestin 2 recruitment to the serotonin 2A receptor
Published in Archives of toxicology (01-10-2020)“…Serotonergic psychedelics, substances exerting their effects primarily through the serotonin 2A receptor (5-HT 2A R), continue to comprise a substantial…”
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Remote HbA 1c testing via microsampling: fit for purpose?
Published in Clinical chemistry and laboratory medicine (26-01-2024)“…The collection of capillary blood microsamples via finger-prick has several advantages over traditional blood collection. It is considered convenient and more…”
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In vitro assays for the functional characterization of (psychedelic) substances at the serotonin receptor 5-HT 2A R
Published in Journal of neurochemistry (01-07-2022)“…Serotonergic psychedelics are substances that induce alterations in mood, perception, and thought, and have the activation of serotonin (5-HT) 2A receptors…”
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In vitro functional characterization of a panel of non-fentanyl opioid new psychoactive substances
Published in Archives of toxicology (01-11-2020)“…The landscape of new psychoactive substances (NPS) is constantly evolving, with new compounds entering the illicit drug market at a continuous pace. Of these,…”
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Liquid chromatography-tandem mass spectrometry for therapeutic drug monitoring of immunosuppressants and creatinine from a single dried blood spot using the Capitainer® qDBS device
Published in Analytica chimica acta (15-02-2023)“…In recent years, a lot of attention has been given to a more patient-centric therapeutic drug monitoring (TDM) of immunosuppressant drugs (tacrolimus,…”
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