Search Results - "STOPPER, Helga"

Cell survival after DNA damage in the comet assay by Bankoglu, Ezgi Eyluel, Schuele, Carolin, Stopper, Helga

“…The comet assay is widely used in basic research, genotoxicity testing, and human biomonitoring. However, interpretation of the comet assay data might benefit…”
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Minimum Information for Reporting on the Comet Assay (MIRCA): recommendations for describing comet assay procedures and results by Møller, Peter, Azqueta, Amaya, Boutet-Robinet, Elisa, Koppen, Gudrun, Bonassi, Stefano, Milić, Mirta, Gajski, Goran, Costa, Solange, Teixeira, João Paulo, Costa Pereira, Cristiana, Dusinska, Maria, Godschalk, Roger, Brunborg, Gunnar, Gutzkow, Kristine B., Giovannelli, Lisa, Cooke, Marcus S., Richling, Elke, Laffon, Blanca, Valdiglesias, Vanessa, Basaran, Nursen, Del Bo’, Cristian, Zegura, Bojana, Novak, Matjaz, Stopper, Helga, Vodicka, Pavel, Vodenkova, Sona, de Andrade, Vanessa Moraes, Sramkova, Monika, Gabelova, Alena, Collins, Andrew, Langie, Sabine A. S.

“…The comet assay is a widely used test for the detection of DNA damage and repair activity. However, there are interlaboratory differences in reported levels of…”
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Effect of cryopreservation on DNA damage and DNA repair activity in human blood samples in the comet assay by Bankoglu, Ezgi Eyluel, Stipp, Franzisca, Gerber, Johanna, Seyfried, Florian, Heidland, August, Bahner, Udo, Stopper, Helga

“…The comet assay is a commonly used method to determine DNA damage and repair activity in many types of samples. In recent years, the use of the comet assay in…”
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DNA Damage in Chronic Kidney Disease: Evaluation of Clinical Biomarkers by Schupp, Nicole, Heidland, A., Stopper, Helga

“…Patients with chronic kidney disease (CKD) exhibit an increased cancer risk compared to a healthy control population. To be able to estimate the cancer risk of…”
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Micronucleus frequency in buccal mucosa cells of patients with neurodegenerative diseases by Reimann, Hauke, Stopper, Helga, Polak, Thomas, Lauer, Martin, Herrmann, Martin J., Deckert, Jürgen, Hintzsche, Henning

“…Neurodegenerative diseases show an increase in prevalence and incidence, with the most prominent example being Alzheimer’s disease. DNA damage has been…”
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The Plant Hormone Cytokinin Confers Protection against Oxidative Stress in Mammalian Cells by Othman, Eman M, Naseem, Muhammed, Awad, Eman, Dandekar, Thomas, Stopper, Helga

“…Modulating key dynamics of plant growth and development, the effects of the plant hormone cytokinin on animal cells gained much attention recently. Most…”
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Signaling steps in the induction of genomic damage by insulin in colon and kidney cells by Othman, Eman Maher, Hintzsche, Henning, Stopper, Helga

“…Diabetes mellitus (DM), a disease with almost 350 million people affected worldwide, will be the seventh leading cause of death by 2030. Diabetic patients…”
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Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines by STRESEMANN, Carlo, BRUECKNER, Bodo, MUSCH, Tanja, STOPPER, Helga, LYKO, Frank

“…DNA methyltransferase inhibitors represent promising new drugs for cancer therapies. The first of these compounds (5-azacytidine, Vidaza) has recently been…”
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Role of PTEN in Oxidative Stress and DNA Damage in the Liver of Whole-Body Pten Haplodeficient Mice by Bankoglu, Ezgi Eyluel, Tschopp, Oliver, Schmitt, Johannes, Burkard, Philipp, Jahn, Daniel, Geier, Andreas, Stopper, Helga

“…Type 2 diabetes (T2DM) and obesity are frequently associated with non-alcoholic fatty liver disease (NAFLD) and with an elevated cancer incidence. The…”
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Integrated structural and functional analysis of the protective effects of kinetin against oxidative stress in mammalian cellular systems by Naseem, Muhammad, Othman, Eman M., Fathy, Moustafa, Iqbal, Jibran, Howari, Fares M., AlRemeithi, Fatima A., Kodandaraman, Geema, Stopper, Helga, Bencurova, Elena, Vlachakis, Dimitrios, Dandekar, Thomas

“…Metabolism and signaling of cytokinins was first established in plants, followed by cytokinin discoveries in all kingdoms of life. However, understanding of…”
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Disruptive effects of plasticizers bisphenol A, F, and S on steroidogenesis of adrenocortical cells by Pötzl, Benedikt, Kürzinger, Lydia, Kendl, Sabine, Stopper, Helga, Kurlbaum, Max, Fassnacht, Martin, Dischinger, Ulrich

“…Endocrine disrupting chemicals (EDCs) are known to interfere with endocrine homeostasis. Their impact on the adrenal cortex and steroidogenesis has not yet…”
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Isolation of Petrocidin A, a New Cytotoxic Cyclic Dipeptide from the Marine Sponge-Derived Bacterium Streptomyces sp. SBT348 by Cheng, Cheng, Othman, Eman M, Stopper, Helga, Edrada-Ebel, RuAngelie, Hentschel, Ute, Abdelmohsen, Usama Ramadan

“…A new cyclic dipeptide, petrocidin A ( ), along with three known compounds-2,3-dihydroxybenzoic acid ( ), 2,3-dihydroxybenzamide ( ), and maltol ( )-were…”
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Terahertz electromagnetic fields (0.106 THz) do not induce manifest genomic damage in vitro by Hintzsche, Henning, Jastrow, Christian, Kleine-Ostmann, Thomas, Kärst, Uwe, Schrader, Thorsten, Stopper, Helga

“…Terahertz electromagnetic fields are non-ionizing electromagnetic fields in the frequency range from 0.1 to 10 THz. Potential applications of these…”
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Benfotiamine exhibits direct antioxidative capacity and prevents induction of DNA damage in vitro by Schmid, Ursula, Stopper, Helga, Heidland, August, Schupp, Nicole

“…Background Complications in diabetes mellitus are partially mediated by enhanced formation of reactive oxygen species. Among the factors involved in reactive…”
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Ageloline A, new antioxidant and antichlamydial quinolone from the marine sponge-derived bacterium Streptomyces sp. SBT345 by Cheng, Cheng, Othman, Eman M., Reimer, Anastasija, Grüne, Matthias, Kozjak-Pavlovic, Vera, Stopper, Helga, Hentschel, Ute, Abdelmohsen, Usama R.

“…[Display omitted] •A new chlorinated quinolone was isolated from the sponge-associated Streptomyces sp. SBT345.•Ageloline A showed antioxidant…”
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Effects of Resveratrol, Lovastatin and the mTOR-Inhibitor RAD-001 on Insulin-Induced Genomic Damage In Vitro by Awad, Eman, Othman, Eman M, Stopper, Helga

“…Diabetes mellitus (DM) is one of the major current health problems due to lifestyle changes. Before diagnosis and in the early years of disease, insulin blood…”
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Oxidative Stress and DNA Damage in Peripheral Blood Mononuclear Cells from Normal, Obese, Prediabetic and Diabetic Persons Exposed to Thyroid Hormone In Vitro by Djelić, Ninoslav, Borozan, Sunčica, Dimitrijević-Srećković, Vesna, Pajović, Nevena, Mirilović, Milorad, Stopper, Helga, Stanimirović, Zoran

“…Diabetes, a chronic group of medical disorders characterized byhyperglycemia, has become a global pandemic. Some hormones may influence the course and outcome…”
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Metabolomic profiling and biological investigation of the marine sponge‐derived bacterium Rhodococcus sp. UA13 by Elsayed, Yasmin, Refaat, John, Abdelmohsen, Usama Ramadan, Othman, Eman Maher, Stopper, Helga, Fouad, Mostafa Ahmed

“…Introduction Marine sponge‐associated actinomycetes are potent sources of bioactive natural products of pharmaceutical significance. They also contributed to…”
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Improving VAE based molecular representations for compound property prediction by Tevosyan, Ani, Khondkaryan, Lusine, Khachatrian, Hrant, Tadevosyan, Gohar, Apresyan, Lilit, Babayan, Nelly, Stopper, Helga, Navoyan, Zaven

“…Collecting labeled data for many important tasks in chemoinformatics is time consuming and requires expensive experiments. In recent years, machine learning…”
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A Multi-Endpoint Approach to Base Excision Repair Incision Activity Augmented by PARylation and DNA Damage Levels in Mice: Impact of Sex and Age by Winkelbeiner, Nicola, Wandt, Viktoria K, Ebert, Franziska, Lossow, Kristina, Bankoglu, Ezgi E, Martin, Maximilian, Mangerich, Aswin, Stopper, Helga, Bornhorst, Julia, Kipp, Anna P, Schwerdtle, Tanja

“…Investigation of processes that contribute to the maintenance of genomic stability is one crucial factor in the attempt to understand mechanisms that…”
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