Search Results - "STOKES PEEBLES, R"
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IL-33 promotes the egress of group 2 innate lymphoid cells from the bone marrow
Published in The Journal of experimental medicine (02-01-2018)“…Group 2 innate lymphoid cells (ILC2s) are effector cells within the mucosa and key participants in type 2 immune responses in the context of allergic…”
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2
Testosterone Decreases House Dust Mite-Induced Type 2 and IL-17A-Mediated Airway Inflammation
Published in The Journal of immunology (1950) (01-10-2018)“…As adults, women are twice as likely as men to have asthma; however, the mechanisms explaining this sexual dimorphism remain unclear. Increased type 2…”
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3
Proinflammatory Pathways in the Pathogenesis of Asthma
Published in Clinics in chest medicine (01-03-2019)“…There are multiple proinflammatory pathways in the pathogenesis of asthma. These include both innate and adaptive inflammation, in addition to inflammatory and…”
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4
IL-13 Protects against SARS-CoV-2?
Published in American journal of respiratory cell and molecular biology (01-04-2022)“…Peebles Jr discusses the paper by Bonser et al which examines the effects of IL-13 on SARS-CoV-2 infection of differentiated human bronchial epithelial cells…”
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5
Respiratory syncytial virus infection during infancy and asthma during childhood in the USA (INSPIRE): a population-based, prospective birth cohort study
Published in The Lancet (British edition) (20-05-2023)“…Early-life severe respiratory syncytial virus (RSV) infection has been associated with the onset of childhood wheezing illnesses. However, the relationship…”
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6
Th17-mediated inflammation in asthma
Published in Current opinion in immunology (01-12-2013)“…Highlights • Th17 cells and cytokines are associated with the more severe phenotypes of asthma. • IL-17A and IL-17F are associated with increased neutrophils…”
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7
Respiratory syncytial virus infection activates IL-13–producing group 2 innate lymphoid cells through thymic stromal lymphopoietin
Published in Journal of allergy and clinical immunology (01-09-2016)“…Background Respiratory syncytial virus (RSV) is a major health care burden with a particularly high worldwide morbidity and mortality rate among infants. Data…”
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8
Race toward more equitable pulmonary function testing?
Published in Annals of allergy, asthma, & immunology (01-10-2024)Get full text
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9
Innate Type 2 Responses to Respiratory Syncytial Virus Infection
Published in Viruses (08-05-2020)“…Respiratory syncytial virus (RSV) is a common and contagious virus that results in acute respiratory tract infections in infants. In many cases, the symptoms…”
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10
Prostaglandins in asthma and allergic diseases
Published in Pharmacology & therapeutics (Oxford) (01-01-2019)“…Prostaglandins are synthesized through the metabolism of arachidonic acid via the cyclooxygenase pathway. There are five primary prostaglandins, PGD2, PGE2,…”
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11
Androgen receptor signaling promotes Treg suppressive function during allergic airway inflammation
Published in The Journal of clinical investigation (15-02-2022)“…Women have higher prevalence of asthma compared with men. In asthma, allergic airway inflammation is initiated by IL-33 signaling through ST2, leading to…”
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12
Glucagon-like peptide 1 signaling inhibits allergen-induced lung IL-33 release and reduces group 2 innate lymphoid cell cytokine production in vivo
Published in Journal of allergy and clinical immunology (01-11-2018)“…IL-33 is one of the most consistently associated gene candidates for asthma identified by using a genome-wide association study. Studies in mice and in human…”
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13
Glucagon‐like peptide‐1 receptor agonist inhibits aeroallergen‐induced activation of ILC2 and neutrophilic airway inflammation in obese mice
Published in Allergy (Copenhagen) (01-11-2021)“…Background Obesity is a risk factor for the development of asthma. However, pharmacologic therapeutic strategies that specifically target obese asthmatics have…”
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14
Differential Pathogenesis of Respiratory Syncytial Virus Clinical Isolates in BALB/c Mice
Published in Journal of Virology (01-06-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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15
PPAR-γ in Macrophages Limits Pulmonary Inflammation and Promotes Host Recovery following Respiratory Viral Infection
Published in Journal of virology (01-05-2019)“…Alveolar macrophages (AM) play pivotal roles in modulating host defense, pulmonary inflammation, and tissue injury following respiratory viral infections…”
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16
Prostaglandin E2 in NSAID-exacerbated respiratory disease: protection against cysteinyl leukotrienes and group 2 innate lymphoid cells
Published in Current opinion in allergy and clinical immunology (01-02-2019)“…PURPOSE OF REVIEWThe purpose of this review is to describe the recent advances that have been made in understanding the protective role of prostaglandin E2…”
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Nasopharyngeal Lactobacillus is associated with a reduced risk of childhood wheezing illnesses following acute respiratory syncytial virus infection in infancy
Published in Journal of allergy and clinical immunology (01-11-2018)“…Early life acute respiratory infection (ARI) with respiratory syncytial virus (RSV) has been strongly associated with the development of childhood wheezing…”
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18
Eosinophils Express LTA4 Hydrolase and Synthesize LTB4: Important for Asthma Pathogenesis?
Published in American journal of respiratory cell and molecular biology (01-04-2019)“…Peripheral blood eosinophils cultured in vitro produced LTB4 when unstimulated, and they released significantly elevated levels of LTB4 when stimulated with…”
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19
Group 2 Innate Lymphoid Cells Coordinate Damage Response in the Stomach
Published in Gastroenterology (New York, N.Y. 1943) (01-12-2020)“…Severe injury to the lining of the stomach leads to changes in the epithelium (reprogramming) that protect and promote repair of the tissue, including…”
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20
MUCing up the airway in asthma
Published in Journal of allergy and clinical immunology (01-12-2021)Get full text
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