Search Results - "STOCZYNSKA, Ewelina"
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BCR/ABL Stimulates WRN to Promote Survival and Genomic Instability
Published in Cancer research (Chicago, Ill.) (01-02-2011)“…BCR/ABL-transformed chronic myeloid leukemia (CML) cells accumulate numerous DNA double-strand breaks (DSB) induced by reactive oxygen species (ROS) and…”
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Generation of human iPSCs from cells of fibroblastic and epithelial origin by means of the oriP/EBNA-1 episomal reprogramming system
Published in Stem cell research & therapy (19-06-2015)“…The prospect of therapeutic applications of the induced pluripotent stem cells (iPSCs) is based on their ability to generate virtually any cell type present in…”
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3
EGFR Activation Leads to Cell Death Independent of PI3K/AKT/mTOR in an AD293 Cell Line
Published in PloS one (06-05-2016)“…The Epidermal Growth Factor Receptor (EGFR) and its mutations contribute in various ways to tumorigenesis and biology of human cancers. They are associated…”
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Regeneration difficulties in patients with FQAD can limit the use of iPSc-based cell therapy
Published in Stem cell research & therapy (21-05-2022)“…Etiopathogenesis of fluoroquinolone-associated disability (FQAD) syndrome is not fully understood, yet research could progress by utilizing induced pluripotent…”
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A way to understand idiopathic senescence and apoptosis in primary glioblastoma cells - possible approaches to circumvent these phenomena
Published in BMC cancer (14-09-2019)“…Glioblastoma (GB) is considered one of the most lethal tumors. Extensive research at the molecular level may enable to gain more profound insight into its…”
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6
Proteomic and Transcriptomic Landscapes of Alström and Bardet-Biedl Syndromes
Published in Genes (15-12-2022)“…Alström syndrome (ALMS) and Bardet-Biedl syndrome (BBS) are rare genetic diseases with a number of common clinical features ranging from early-childhood…”
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SOX2 and SOX2-MYC Reprogramming Process of Fibroblasts to the Neural Stem Cells Compromised by Senescence
Published in PloS one (04-11-2015)“…Tumorigenic potential of induced pluripotent stem cells (iPSCs) infiltrating population of induced neural stem cells (iNSCs) generated from iPSCs may limit…”
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The failure in the stabilization of glioblastoma-derived cell lines: spontaneous in vitro senescence as the main culprit
Published in PloS one (30-01-2014)“…Cell line analysis is an important element of cancer research. Despite the progress in glioblastoma cell culturing, the cells isolated from the majority of…”
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9
IDH1R132H in Neural Stem Cells: Differentiation Impaired by Increased Apoptosis
Published in PloS one (01-05-2016)“…The high frequency of mutations in the isocitrate dehydrogenase 1 (IDH1) gene in diffuse gliomas indicates its importance in the process of gliomagenesis…”
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Increased EGFRvIII Epitope Accessibility after Tyrosine Kinase Inhibitor Treatment of Glioblastoma Cells Creates More Opportunities for Immunotherapy
Published in International journal of molecular sciences (22-02-2023)“…The number of glioblastoma (GB) cases is increasing every year, and the currently available therapies remain ineffective. A prospective antigen for GB therapy…”
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Glioblastoma with BRAFV600E mutation and numerous metastatic foci: a case report
Published in Folia neuropathologica (01-01-2019)“…Glioblastoma, the most malignant astrocytic tumour, is associated with limited survival and thus rare metastases. We analysed a particularly interesting case –…”
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Phenotypical Flexibility of the EGFRvIII-Positive Glioblastoma Cell Line and the Multidirectional Influence of TGFβ and EGF on These Cells—EGFRvIII Appears as a Weak Oncogene
Published in International journal of molecular sciences (12-10-2022)“…Background: The biological role of EGFRvIII (epidermal growth factor receptor variant three) remains unclear. Methods: Three glioblastoma DK-MG sublines were…”
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The Genetic Diversity of Proteasome Genes in the T1DM Polish Population
Published in Current diabetes reviews (01-01-2023)“…Autoimmune metabolic diseases generate numerous healthy and social problems. The possible association of SNPs in the ubiquitin-proteasome system (UPS) with…”
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Screening for EGFR amplifications with a novel method and their significance for the outcome of glioblastoma patients
Published in PloS one (06-06-2013)“…Glioblastoma is a highly aggressive tumour of the central nervous system, characterised by poor prognosis irrespective of the applied treatment. The aim of our…”
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Glioblastoma specimens with TP53 mutations do not show EGFRvIII amplification
Published in Cancer genetics (01-05-2011)Get full text
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Limited importance of the dominant-negative effect of TP53 missense mutations
Published in BMC cancer (13-06-2011)“…Heterozygosity of TP53 missense mutations is related to the phenomenon of the dominant-negative effect (DNE). To estimate the importance of the DNE of TP53…”
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Reduced expression of ELAVL4 in male meningioma patients
Published in Brain tumor pathology (01-07-2013)“…Meningioma is a frequently occurring tumor of the central nervous system. Among many genetic alternations, the loss of the short arm of chromosome 1 is the…”
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Immunohistochemical detection of EGFRvIII in glioblastoma – Anti-EGFRvIII antibody validation for diagnostic and CAR-T purposes
Published in Biochemical and biophysical research communications (10-12-2023)“…The emergence of therapies such as CAR-T has created a need for reliable, validated methods for detecting EGFRvIII in patient tumor cells. Particularly so…”
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Assessment of COVID-19 vaccination effectiveness
Published in Alergologia Polska - Polish Journal of Allergology (2022)Get full text
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Gaps and Doubts in Search to Recognize Glioblastoma Cellular Origin and Tumor Initiating Cells
Published in Journal of oncology (2020)“…Cellular origin of glioblastoma (GB) is constantly discussed and remains a controversial subject. Unfortunately, neurobiologists are not consistent in defining…”
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