Search Results - "STINTZI, Alain"

Advancing functional and translational microbiome research using meta-omics approaches by Zhang, Xu, Li, Leyuan, Butcher, James, Stintzi, Alain, Figeys, Daniel

“…The gut microbiome has emerged as an important factor affecting human health and disease. The recent development of -omics approaches, including phylogenetic…”
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Low temperature MBBR nitrification: Microbiome analysis by Young, Bradley, Delatolla, Robert, Kennedy, Kevin, Laflamme, Edith, Stintzi, Alain

“…This study aims to investigate post carbon removal moving bed biofilm reactor (MBBR) nitrification through the transition from 20 °C to 1 °C and during through…”
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Resistant starch, microbiome, and precision modulation by Dobranowski, Peter A., Stintzi, Alain

“…Resistant starch, microbiome, and precision modulation. Mounting evidence has positioned the gut microbiome as a nexus of health. Modulating its phylogenetic…”
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Functional impacts of the intestinal microbiome in the pathogenesis of inflammatory bowel disease by Li, Jennifer, Butcher, James, Mack, David, Stintzi, Alain

“…: The human intestinal microbiome plays a critical role in human health and disease, including the pathogenesis of inflammatory bowel disease (IBD). Numerous…”
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Metaproteomics reveals associations between microbiome and intestinal extracellular vesicle proteins in pediatric inflammatory bowel disease by Zhang, Xu, Deeke, Shelley A., Ning, Zhibin, Starr, Amanda E., Butcher, James, Li, Jennifer, Mayne, Janice, Cheng, Kai, Liao, Bo, Li, Leyuan, Singleton, Ruth, Mack, David, Stintzi, Alain, Figeys, Daniel

“…Alterations in gut microbiota have been implicated in the pathogenesis of inflammatory bowel disease (IBD), however factors that mediate the host–microbiota…”
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Widespread protein lysine acetylation in gut microbiome and its alterations in patients with Crohn’s disease by Zhang, Xu, Ning, Zhibin, Mayne, Janice, Yang, Yidai, Deeke, Shelley A., Walker, Krystal, Farnsworth, Charles L., Stokes, Matthew P., Couture, Jean-François, Mack, David, Stintzi, Alain, Figeys, Daniel

“…Lysine acetylation (Kac), an abundant post-translational modification (PTM) in prokaryotes, regulates various microbial metabolic pathways. However, no studies…”
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Altered intestinal microbiota–host mitochondria crosstalk in new onset Crohn’s disease by Mottawea, Walid, Chiang, Cheng-Kang, Mühlbauer, Marcus, Starr, Amanda E., Butcher, James, Abujamel, Turki, Deeke, Shelley A., Brandel, Annette, Zhou, Hu, Shokralla, Shadi, Hajibabaei, Mehrdad, Singleton, Ruth, Benchimol, Eric I., Jobin, Christian, Mack, David R., Figeys, Daniel, Stintzi, Alain

“…Intestinal microbial dysbiosis is associated with Crohn’s disease (CD). However, the mechanisms leading to the chronic mucosal inflammation that characterizes…”
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The transcriptional landscape of Campylobacter jejuni under iron replete and iron limited growth conditions by Butcher, James, Stintzi, Alain

“…The genome-wide Campylobacter jejuni transcriptional response under iron replete and iron limited conditions was characterized using RNA-seq. We have…”
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An in vitro model maintaining taxon-specific functional activities of the gut microbiome by Li, Leyuan, Abou-Samra, Elias, Ning, Zhibin, Zhang, Xu, Mayne, Janice, Wang, Janet, Cheng, Kai, Walker, Krystal, Stintzi, Alain, Figeys, Daniel

“…In vitro gut microbiome models could provide timely and cost-efficient solutions to study microbiome responses to drugs. For this purpose, in vitro models that…”
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Defining the vulnerable period for re-establishment of Clostridium difficile colonization after treatment of C. difficile infection with oral vancomycin or metronidazole by Abujamel, Turki, Cadnum, Jennifer L, Jury, Lucy A, Sunkesula, Venkata C K, Kundrapu, Sirisha, Jump, Robin L, Stintzi, Alain C, Donskey, Curtis J

“…Clostridium difficile is an anaerobic, spore-forming bacterium that is the most common cause of healthcare-associated diarrhea in developed countries. A…”
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Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota by Arthur, Janelle C., Perez-Chanona, Ernesto, Mühlbauer, Marcus, Tomkovich, Sarah, Uronis, Joshua M., Fan, Ting-Jia, Campbell, Barry J., Abujamel, Turki, Dogan, Belgin, Rogers, Arlin B., Rhodes, Jonathan M., Stintzi, Alain, Simpson, Kenneth W., Hansen, Jonathan J., Keku, Temitope O., Fodor, Anthony A., Jobin, Christian

“…Inflammation alters host physiology to promote cancer, as seen in colitis-associated colorectal cancer (CRC). Here, we identify the intestinal microbiota as a…”
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Gene Expression Profile of Campylobacter jejuni in Response to Growth Temperature Variation by Stintzi, Alain

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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RapidAIM: a culture- and metaproteomics-based Rapid Assay of Individual Microbiome responses to drugs by Li, Leyuan, Ning, Zhibin, Zhang, Xu, Mayne, Janice, Cheng, Kai, Stintzi, Alain, Figeys, Daniel

“…Human-targeted drugs may exert off-target effects or can be repurposed to modulate the gut microbiota. However, our understanding of such effects is limited…”
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Blenderized Enteral Nutrition Diet Study: Feasibility, Clinical, and Microbiome Outcomes of Providing Blenderized Feeds Through a Gastric Tube in a Medically Complex Pediatric Population by Gallagher, Kelsey, Flint, Annika, Mouzaki, Marialena, Carpenter, Andrea, Haliburton, Beth, Bannister, Louise, Norgrove, Holly, Hoffman, Lisa, Mack, David, Stintzi, Alain, Marcon, Margaret

“…Background Chronically ill children often require feeding via gastrostomy tubes (G‐tubes). Commercial formula is most commonly used for enteral feeding;…”
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MetaLab: an automated pipeline for metaproteomic data analysis by Cheng, Kai, Ning, Zhibin, Zhang, Xu, Li, Leyuan, Liao, Bo, Mayne, Janice, Stintzi, Alain, Figeys, Daniel

“…Research involving microbial ecosystems has drawn increasing attention in recent years. Studying microbe-microbe, host-microbe, and environment-microbe…”
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L-Fucose utilization provides Campylobacter jejuni with a competitive advantage by Stahl, Martin, Friis, Lorna M., Nothaft, Harald, Liu, Xin, Li, Jianjun, Szymanski, Christine M., Stintzi, Alain, Cossart, Pascale

“…Campylobacter jejuni is a prevalent gastrointestinal pathogen in humans and a common commensal of poultry. When colonizing its hosts, C. jejuni comes into…”
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The mucosal–luminal interface: an ideal sample to study the mucosa-associated microbiota and the intestinal microbial biogeography by Mottawea, Walid, Butcher, James, Li, Jennifer, Abujamel, Turki, Manoogian, Juliana, Mack, David, Stintzi, Alain

“…Background Alterations in gastrointestinal microbial communities have been linked to human disease. Most studies use fecal samples as a proxy for the…”
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Meso and micro-scale response of post carbon removal nitrifying MBBR biofilm across carrier type and loading by Young, Bradley, Banihashemi, Bahman, Forrest, Daina, Kennedy, Kevin, Stintzi, Alain, Delatolla, Robert

“…This study investigates the effects of three specific moving bed biofilm reactor (MBBR) carrier types and two surface area loading rates on biofilm thickness,…”
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Virome Sequencing of the Human Intestinal Mucosal-Luminal Interface by Yan, Austin, Butcher, James, Mack, David, Stintzi, Alain

“…While the human gut virome has been increasingly explored in recent years, nearly all studies have been limited to fecal sampling. The mucosal-luminal…”
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Structure and regulon of Campylobacter jejuni ferric uptake regulator Fur define apo-Fur regulation by Butcher, James, Sarvan, Sabina, Brunzelle, Joseph S, Couture, Jean-François, Stintzi, Alain

“…The full regulatory potential of the ferric uptake regulator (Fur) family of proteins remains undefined despite over 20 years of study. We report herein an…”
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