Search Results - "STINE, A"

Environmental factors in declining human fertility by Skakkebæk, Niels E., Lindahl-Jacobsen, Rune, Levine, Hagai, Andersson, Anna-Maria, Jørgensen, Niels, Main, Katharina M., Lidegaard, Øjvind, Priskorn, Lærke, Holmboe, Stine A., Bräuner, Elvira V., Almstrup, Kristian, Franca, Luiz R., Znaor, Ariana, Kortenkamp, Andreas, Hart, Roger J., Juul, Anders

“…A severe decline in child births has occurred over the past half century, which will lead to considerable population declines, particularly in industrialized…”
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Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies by Berg, Kaja C G, Eide, Peter W, Eilertsen, Ina A, Johannessen, Bjarne, Bruun, Jarle, Danielsen, Stine A, Bjørnslett, Merete, Meza-Zepeda, Leonardo A, Eknæs, Mette, Lind, Guro E, Myklebost, Ola, Skotheim, Rolf I, Sveen, Anita, Lothe, Ragnhild A

“…Colorectal cancer (CRC) cell lines are widely used pre-clinical model systems. Comprehensive insights into their molecular characteristics may improve model…”
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Do "Brain-Training" Programs Work? by Simons, Daniel J., Boot, Walter R., Charness, Neil, Gathercole, Susan E., Chabris, Christopher F., Hambrick, David Z., Stine-Morrow, Elizabeth A. L.

“…In 2014, two groups of scientists published open letters on the efficacy of brain-training interventions, or "brain games," for improving cognition. The first…”
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P4-ATPases as Phospholipid Flippases-Structure, Function, and Enigmas by Andersen, Jens P, Vestergaard, Anna L, Mikkelsen, Stine A, Mogensen, Louise S, Chalat, Madhavan, Molday, Robert S

“…P4-ATPases comprise a family of P-type ATPases that actively transport or flip phospholipids across cell membranes. This generates and maintains membrane lipid…”
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Convection-Enhanced Delivery: Connection to and Impact of Interstitial Fluid Flow by Stine, Caleb A., Munson, Jennifer M.

“…Convection-enhanced delivery (CED) is a method used to increase transport of therapeutics in and around brain tumors. CED works through locally applying a…”
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Colorectal Cancer Consensus Molecular Subtypes Translated to Preclinical Models Uncover Potentially Targetable Cancer Cell Dependencies by Sveen, Anita, Bruun, Jarle, Eide, Peter W, Eilertsen, Ina A, Ramirez, Lorena, Murumägi, Astrid, Arjama, Mariliina, Danielsen, Stine A, Kryeziu, Kushtrim, Elez, Elena, Tabernero, Josep, Guinney, Justin, Palmer, Hector G, Nesbakken, Arild, Kallioniemi, Olli, Dienstmann, Rodrigo, Lothe, Ragnhild A

“…Response to standard oncologic treatment is limited in colorectal cancer. The gene expression-based consensus molecular subtypes (CMS) provide a new paradigm…”
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Arctic tree rings as recorders of variations in light availability by Stine, A. R., Huybers, P.

“…Annual growth ring variations in Arctic trees are often used to reconstruct surface temperature. In general, however, the growth of Arctic vegetation is…”
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Changes in the phase of the annual cycle of surface temperature by Stine, A. R., Huybers, P., Fung, I. Y.

“…The annual cycle in the Earth’s surface temperature is extremely large—comparable in magnitude to the glacial–interglacial cycles over most of the planet…”
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Global Surface Temperature Response to 11-Yr Solar Cycle Forcing Consistent with General Circulation Model Results by Amdur, T., Stine, A. R., Huybers, P.

“…The 11-yr solar cycle is associated with a roughly 1 W m−2 trough-to-peak variation in total solar irradiance and is expected to produce a global temperature…”
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Phosphatidylserine flipping by the P4-ATPase ATP8A2 is electrogenic by Tadini-Buoninsegni, Francesco, Mikkelsen, Stine A., Mogensen, Louise S., Molday, Robert S., Andersen, Jens Peter

“…Phospholipid flippases (P4-ATPases) utilize ATP to translocate specific phospholipids from the exoplasmic leaflet to the cytoplasmic leaflet of biological…”
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How pregnant women with diabetes experience telemonitoring of the fetal heart rate – An interview study by Jepsen, Ingrid, Nielsen, Jane H., Eriksen, Stine A., Maimburg, Rikke D.

“…•This paper adds important new knowledge about the experience of telemonitoring.•Women found the benefits of telemonitoring to outweigh the…”
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A Darier disease mutation relieves kinetic constraints imposed by the tail of sarco(endo)plasmic reticulum Ca2+-ATPase 2b by Mikkelsen, Stine A., Vangheluwe, Peter, Andersen, Jens Peter

“…The sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) 2b isoform possesses an extended C terminus (SERCA2b tail) forming an 11th transmembrane (TM) helix, which…”
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Ovarian follicular fluid levels of phthalates and benzophenones in relation to fertility outcomes by Beck, Astrid L., Rehfeld, Anders, Mortensen, Li J., Lorenzen, Mette, Andersson, Anna-Maria, Juul, Anders, Bentin-Ley, Ursula, Krog, Hans, Frederiksen, Hanne, Petersen, Jørgen H., Holmboe, Stine A., Jensen, Martin Blomberg

“…Many endocrine disrupting chemicals (EDCs), for instance phthalates and benzophenones, are associated with adverse fertility outcomes and semen quality…”
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Critical roles of isoleucine-364 and adjacent residues in a hydrophobic gate control of phospholipid transport by the mammalian P4-ATPase ATP8A2 by Vestergaard, Anna L, Coleman, Jonathan A, Lemmin, Thomas, Mikkelsen, Stine A, Molday, Laurie L, Vilsen, Bente, Molday, Robert S, Dal Peraro, Matteo, Andersen, Jens Peter

“…P4-ATPases (flippases) translocate specific phospholipids such as phosphatidylserine from the exoplasmic leaflet of the cell membrane to the cytosolic leaflet,…”
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CpG island methylator phenotype identifies high risk patients among microsatellite stable BRAF mutated colorectal cancers by Vedeld, Hege Marie, Merok, Marianne, Jeanmougin, Marine, Danielsen, Stine A., Honne, Hilde, Presthus, Gro Kummeneje, Svindland, Aud, Sjo, Ole H., Hektoen, Merete, Eknæs, Mette, Nesbakken, Arild, Lothe, Ragnhild A., Lind, Guro E.

“…The prognostic value of CpG island methylator phenotype (CIMP) in colorectal cancer remains unsettled. We aimed to assess the prognostic value of this…”
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Using assessment criteria for pesticides to evaluate the endocrine disrupting potential of non-pesticide chemicals: Case butylparaben by Boberg, Julie, Johansson, Hanna K.L., Axelstad, Marta, Olsen, Gustav P.M., Johansen, Mathias, Holmboe, Stine A., Andersson, Anna-Maria, Svingen, Terje

“…•In-depth analysis identifies butylparaben as an endocrine disruptor.•Butylparaben shows estrogenic MoA and adverse effect on sperm in rodent…”
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Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study by Domingo, Enric, Freeman-Mills, Luke, Rayner, Emily, Glaire, Mark, Briggs, Sarah, Vermeulen, Louis, Fessler, Evelyn, Medema, Jan Paul, Boot, Arnoud, Morreau, Hans, van Wezel, Tom, Liefers, Gerrit-Jan, Lothe, Ragnhild A, Danielsen, Stine A, Sveen, Anita, Nesbakken, Arild, Zlobec, Inti, Lugli, Alessandro, Koelzer, Viktor H, Berger, Martin D, Castellví-Bel, Sergi, Muñoz, Jenifer, de Bruyn, Marco, Nijman, Hans W, Novelli, Marco, Lawson, Kay, Oukrif, Dahmane, Frangou, Eleni, Dutton, Peter, Tejpar, Sabine, Delorenzi, Mauro, Kerr, Rachel, Kerr, David, Tomlinson, Ian, Church, David N

“…Precision cancer medicine depends on defining distinct tumour subgroups using biomarkers that may occur at very modest frequencies. One such subgroup comprises…”
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Implications of Liebig's law of the minimum for tree-ring reconstructions of climate by Stine, A R, Huybers, P

“…A basic principle of ecology, known as Liebig's Law of the Minimum, is that plant growth reflects the strongest limiting environmental factor. This principle…”
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On the track of the lipid transport pathway of the phospholipid flippase ATP8A2 - Mutation analysis of residues of the transmembrane segments M1, M2, M3 and M4 by Mogensen, Louise S., Mikkelsen, Stine A., Tadini-Buoninsegni, Francesco, Holm, Rikke, Matsell, Eli, Vilsen, Bente, Molday, Robert S., Andersen, Jens Peter

“…P4-ATPases, also known as flippases, translocate specific lipids from the exoplasmic leaflet to the cytoplasmic leaflet of biological membranes, thereby…”
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Electrogenic reaction step and phospholipid translocation pathway of the mammalian P4‐ATPase ATP8A2 by Tadini‐Buoninsegni, Francesco, Mikkelsen, Stine A., Mogensen, Louise S., Holm, Rikke, Molday, Robert S., Andersen, Jens Peter

“…ATP8A2 is a mammalian P4‐ATPase (flippase) that translocates the negatively charged lipid substrate phosphatidylserine from the exoplasmic leaflet to the…”
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