Search Results - "STEWART, C. L"
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A new linear regression-like residual for survival analysis, with application to genome wide association studies of time-to-event data
Published in PloS one (04-05-2020)“…In linear regression, a residual measures how far a subject's observation is from expectation; in survival analysis, a subject's Martingale or deviance…”
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Brd2 haploinsufficiency extends lifespan and healthspan in C57B6/J mice
Published in PloS one (19-06-2020)“…Aging in mammals is the gradual decline of an organism's physical, mental, and physiological capacity. Aging leads to increased risk for disease and eventually…”
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Prediction of short-term neonatal complications in preterm infants using exome-wide genetic variation and gestational age: a pilot study
Published in Pediatric research (01-10-2020)“…Background Preterm birth is the leading cause of mortality and morbidity in young children, with over a million deaths per year worldwide arising from neonatal…”
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BioNetGMMFit: estimating parameters of a BioNetGen model from time-stamped snapshots of single cells
Published in NPJ systems biology and applications (22-09-2023)“…Mechanistic models are commonly employed to describe signaling and gene regulatory kinetics in single cells and cell populations. Recent advances in…”
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Investigation of cutaneous photoadaptation to narrowband ultraviolet B
Published in British journal of dermatology (1951) (01-02-2014)“…Summary Background Photoadaptation describes the skin's ability to withstand an increased dose of ultraviolet (UV) radiation with repeated exposure, and this…”
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The immune reconstitution of the skin following sex‐mismatched allogeneic haematopoietic stem cell transplant: a prospective case series utilizing fluorescence in situ hybridization and immunohistochemistry
Published in British journal of dermatology (1951) (01-01-2018)Get full text
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Recessive resistance to thyroid hormone in mice lacking thyroid hormone receptor beta: evidence for tissue‐specific modulation of receptor function
Published in The EMBO journal (17-06-1996)“…The diverse functions of thyroid hormone (T3) are presumed to be mediated by two genes encoding the related receptors, TRalpha and TRbeta. However, the in vivo…”
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Positive Selection of Natural Autoreactive B Cells
Published in Science (American Association for the Advancement of Science) (02-07-1999)“…Lymphocyte development is critically influenced by self-antigens. T cells are subject to both positive and negative selection, depending on their degree of…”
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Pathogenic EFHC1 mutations are tolerated in healthy individuals dependent on reported ancestry
Published in Epilepsia (Copenhagen) (01-02-2015)“…Summary Objective Screening for specific coding mutations in the EFHC1 gene has been proposed as a means of assessing susceptibility to juvenile myoclonic…”
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10
On the representation of integers by binary forms
Published in Mathematische annalen (08-10-2019)“…Let F be a binary form with integer coefficients, non-zero discriminant and degree d with d at least 3. Let R F ( Z ) denote the number of integers of absolute…”
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A Pragmatic Test for Detecting Association between a Dichotomous Trait and the Genotypes of Affected Families, Controls and Independent Cases
Published in Frontiers in genetics (09-05-2017)“…The efficient analysis of hybrid designs [e.g., affected families, controls, and (optionally) independent cases] is attractive because it should have increased…”
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Disruption of the mouse necdin gene results in early post-natal lethality
Published in Nature genetics (01-10-1999)“…Prader-Willi syndrome (PWS) is a neurobehavioural disorder characterized by neonatal respiratory depression, hypotonia and failure to thrive in infancy,…”
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Normal spatial learning despite regional inhibition of LTP in mice lacking Thy-1
Published in Nature (London) (29-02-1996)“…The process of learning involves stable changes in synaptic efficacy for which long-term potentiation (LTP) provides a widely adopted mammalian model. Synaptic…”
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14
In Response: ME2 association analysis in adolescent‐onset genetic generalized epilepsy
Published in Epilepsia (Copenhagen) (01-09-2019)Get full text
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15
Clopidogrel: mechanisms of action and review of the evidence relating to use during skin surgery procedures
Published in Clinical and experimental dermatology (01-06-2010)“…Summary Patients who have skin surgery may be taking medication that increases the likelihood of bleeding, such as clopidogrel, aspirin, warfarin, heparin and…”
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A second-generation combined linkage physical map of the human genome
Published in Genome Research (01-12-2007)“…We have completed a second-generation linkage map that incorporates sequence-based positional information. This new map, the Rutgers Map v.2, includes 28,121…”
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Uterine Expression of Leukemia Inhibitory Factor Coincides with the Onset of Blastocyst Implantation
Published in Proceedings of the National Academy of Sciences - PNAS (15-12-1991)“…We have analyzed the expression of the cytokine leukemia inhibitory factor (LIF) during embryogenesis and in tissues of neonatal and adult mice. The site of…”
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Logistic Bayesian LASSO for detecting association combining family and case-control data
Published in BMC proceedings (17-09-2018)“…Because of the limited information from the GAW20 samples when only case-control or trio data are considered, we propose eLBL, an extension of the Logistic…”
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Flow and mixing near a glacier tongue: a pilot study
Published in Ocean science (06-05-2011)“…A glacier tongue floating in the coastal ocean presents a significant obstacle to the local flow and so influences oceanic mixing and transport processes. Here…”
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Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality
Published in Genes & development (15-12-1994)“…Murine embryos that inherit a nonfunctional insulin-like growth factor-II/cation-independent mannose 6-phosphate receptor (Igf2r) gene from their fathers are…”
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