Search Results - "STEVENSON, DAVID K"

The Impact of Hypoxia in Early Pregnancy on Placental Cells by Zhao, Hui, Wong, Ronald J., Stevenson, David K.

“…Oxygen levels in the placental microenvironment throughout gestation are not constant, with severe hypoxic conditions present during the first trimester. This…”
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Replication and refinement of a vaginal microbial signature of preterm birth in two racially distinct cohorts of US women by Callahan, Benjamin J., DiGiulio, Daniel B., Goltsman, Daniela S. Aliaga, Sun, Christine L., Costello, Elizabeth K., Jeganathan, Pratheepa, Biggio, Joseph R., Wong, Ronald J., Druzin, Maurice L., Shaw, Gary M., Stevenson, David K., Holmes, Susan P., Relman, David A.

“…Preterm birth (PTB) is the leading cause of neonatal morbidity and mortality. Previous studies have suggested that the maternal vaginal microbiota contributes…”
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Temporal and spatial variation of the human microbiota during pregnancy by DiGiulio, Daniel B., Callahan, Benjamin J., McMurdie, Paul J., Costello, Elizabeth K., Lyell, Deirdre J., Robaczewska, Anna, Sun, Christine L., Goltsman, Daniela S. A., Wong, Ronald J., Shaw, Gary, Stevenson, David K., Holmes, Susan P., Relman, David A.

“…Despite the critical role of the human microbiota in health, our understanding of microbiota compositional dynamics during and after pregnancy is incomplete…”
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The placental vasculature is affected by changes in gene expression and glycogen-rich cells in a diet-induced obesity mouse model by Zhao, Hui, Wong, Ronald J, Stevenson, David K

“…Maternal obesity is a risk factor for pregnancy complications. Obesity caused by a high-fat diet (HFD) may alter maternal glucose/glycogen metabolism. Here,…”
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Molecular Mechanisms of Pregnancy-Related Vascular Remodeling and Pregnancy Complications by Stevenson, David K, Wong, Ronald J, Nayak, Nihar R

“…The purpose of this editorial is to highlight the various observations made in this Special Issue in the International Journal of Molecular Sciences [...]…”
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Abrupt perturbation and delayed recovery of the vaginal ecosystem following childbirth by Costello, Elizabeth K., DiGiulio, Daniel B., Robaczewska, Anna, Symul, Laura, Wong, Ronald J., Shaw, Gary M., Stevenson, David K., Holmes, Susan P., Kwon, Douglas S., Relman, David A.

“…The vaginal ecosystem is closely tied to human health and reproductive outcomes, yet its dynamics in the wake of childbirth remain poorly characterized. Here,…”
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Explaining the Black-White Disparity in Preterm Birth: A Consensus Statement From a Multi-Disciplinary Scientific Work Group Convened by the March of Dimes by Braveman, Paula, Dominguez, Tyan Parker, Burke, Wylie, Dolan, Siobhan M, Stevenson, David K, Jackson, Fleda Mask, Collins, Jr, James W, Driscoll, Deborah A, Haley, Terinney, Acker, Julia, Shaw, Gary M, McCabe, Edward R B, Hay, Jr, William W, Thornburg, Kent, Acevedo-Garcia, Dolores, Cordero, José F, Wise, Paul H, Legaz, Gina, Rashied-Henry, Kweli, Frost, Jordana, Verbiest, Sarah, Waddell, Lisa

“…In 2017-2019, the March of Dimes convened a workgroup with biomedical, clinical, and epidemiologic expertise to review knowledge of the causes of the…”
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Predischarge Screening for Severe Neonatal Hyperbilirubinemia Identifies Infants Who Need Phototherapy by Bhutani, Vinod K., MD, Stark, Ann R., MD, Lazzeroni, Laura C., PhD, Poland, Ronald, MD, Gourley, Glenn R., MD, Kazmierczak, Steve, PhD, Meloy, Linda, MD, Burgos, Anthony E., MD, Hall, Judith Y., RN, Stevenson, David K., MD

“…Objective To test whether the combined use of total plasma/serum bilirubin (TSB) levels and clinical risk factors more accurately identifies infants who…”
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Unique roles of infiltrating myeloid cells in the murine uterus during early to midpregnancy by Zhao, Hui, Kalish, Flora, Schulz, Stephanie, Yang, Yang, Wong, Ronald J, Stevenson, David K

“…Leukocyte infiltration into the uterus is a characteristic feature in early to midpregnancy, but the composition and function of these leukocytes are not well…”
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Brain microstructural development at near-term age in very-low-birth-weight preterm infants: An atlas-based diffusion imaging study by Rose, Jessica, Vassar, Rachel, Cahill-Rowley, Katelyn, Guzman, Ximena Stecher, Stevenson, David K., Barnea-Goraly, Naama

“…At near-term age the brain undergoes rapid growth and development. Abnormalities identified during this period have been recognized as potential predictors of…”
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Target-agnostic drug prediction integrated with medical record analysis uncovers differential associations of statins with increased survival in COVID-19 patients by Sperry, Megan M, Oskotsky, Tomiko T, Marić, Ivana, Kaushal, Shruti, Takeda, Takako, Horvath, Viktor, Powers, Rani K, Rodas, Melissa, Furlong, Brooke, Soong, Mercy, Prabhala, Pranav, Goyal, Girija, Carlson, Kenneth E, Wong, Ronald J, Kosti, Idit, Le, Brian L, Logue, James, Hammond, Holly, Frieman, Matthew, Stevenson, David K, Ingber, Donald E, Sirota, Marina, Novak, Richard

“…Drug repurposing requires distinguishing established drug class targets from novel molecule-specific mechanisms and rapidly derisking their therapeutic…”
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Publisher Correction: Abrupt perturbation and delayed recovery of the vaginal ecosystem following childbirth by Costello, Elizabeth K., DiGiulio, Daniel B., Robaczewska, Anna, Symul, Laura, Wong, Ronald J., Shaw, Gary M., Stevenson, David K., Holmes, Susan P., Kwon, Douglas S., Relman, David A.

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Natural Selection Has Differentiated the Progesterone Receptor among Human Populations by Li, Jingjing, Hong, Xiumei, Mesiano, Sam, Muglia, Louis J., Wang, Xiaobin, Snyder, Michael, Stevenson, David K., Shaw, Gary M.

“…The progesterone receptor (PGR) plays a central role in maintaining pregnancy and is significantly associated with medical conditions such as preterm birth…”
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A “Gold Standard” Test for Diagnosing and Quantifying Hemolysis in Neonates and Infants by Christensen, Robert D., Bahr, Timothy M., Wong, Ronald J., Vreman, Hendrik J., Bhutani, Vinod K., Stevenson, David K.

“…Identifying “gold standard” diagnostic tests can promote evidence-based neonatology practice. Hemolysis is a pathological shortening of the erythrocyte…”
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Prevention of traumatic stress in mothers of preterms: 6-month outcomes by Shaw, Richard J, St John, Nick, Lilo, Emily, Jo, Booil, Benitz, William, Stevenson, David K, Horwitz, Sarah M

“…Symptoms of posttraumatic stress disorder are a well-recognized phenomenon in mothers of preterm infants, with implications for maternal health and infant…”
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Mid-gestation serum lipidomic profile associations with spontaneous preterm birth are influenced by body mass index by Borkowski, Kamil, Newman, John W, Aghaeepour, Nima, Mayo, Jonathan A, Blazenović, Ivana, Fiehn, Oliver, Stevenson, David K, Shaw, Gary M, Carmichael, Suzan L

“…Spontaneous preterm birth (sPTB) is a major cause of infant morbidity and mortality. While metabolic changes leading to preterm birth are unknown, several…”
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Fetal de novo mutations and preterm birth by Li, Jingjing, Oehlert, John, Snyder, Michael, Stevenson, David K, Shaw, Gary M

“…Preterm birth (PTB) affects ~12% of pregnancies in the US. Despite its high mortality and morbidity, the molecular etiology underlying PTB has been unclear…”
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Effect of sunflower seed oil emollient therapy on newborn infant survival in Uttar Pradesh, India: A community-based, cluster randomized, open-label controlled trial by Kumar, Aarti, Mishra, Shambhavi, Singh, Shambhavi, Ashraf, Sana, Kan, Peiyi, Ghosh, Amit Kumar, Kumar, Alok, Krishna, Raghav, Stevenson, David K, Tian, Lu, Elias, Peter M, Darmstadt, Gary L, Kumar, Vishwajeet

“…Hospitalized preterm infants with compromised skin barrier function treated topically with sunflower seed oil (SSO) have shown reductions in sepsis and…”
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Integrating evidence and causal mapping of factors that influence medication decision-making by pregnant women at risk of hypertensive disorder: protocol for a scoping review by Lee, Yin Jien, Taft, Anita, Stevenson, David K, Darmstadt, Gary L

“…IntroductionIn 2018, the American College of Obstetricians and Gynecologists recommended low-dose aspirin to prevent the onset of pre-eclampsia among women who…”
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Heme oxygenase-1 deficiency promotes severity of sepsis in a non-surgical preterm mouse model by Fujioka, Kazumichi, Kalish, Flora, Zhao, Hui, Wong, Ronald J., Stevenson, David K.

“…Background Sepsis in preterm infants is associated with systemic inflammatory responses. The stress-response protein heme oxygenase-1 (HO-1) has protective…”
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