Search Results - "STERNBERGER, L. A"

Monoclonal Antibodies Distinguish Phosphorylated and Nonphosphorylated Forms of Neurofilaments in situ by Sternberger, Ludwig A., Sternberger, Nancy H.

“…The immunocytochemical staining patterns of 37 neuron-specific monoclonal antibodies previously described fell into four groups: (i) anti-synapse-associated,…”
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Aberrant Neurofilament Phosphorylation in Alzheimer Disease by Sternberger, Nancy H., Sternberger, Ludwig A., Ulrich, Jürg

“…Alzheimer tangles, despite their location in neuronal perikarya, react immunocytochemically with monoclonal antibodies to phosphorylated epitopes of…”
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Blood--Brain Barrier Protein Recognized by Monoclonal Antibody by Sternberger, Nancy H., Sternberger, Ludwig A.

“…An IgG1 mouse monoclonal antibody produced in response to immunization with rat brain homogenate reacted with endothelial cells in the central and peripheral…”
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The unlabeled antibody method: comparison of peroxidase-antiperoxidase with avidin-biotin complex by a new method of quantification by Sternberger, LA, Sternberger, NH

“…Upon plotting of areas against optical densities in immunocytochemically stained tissue sections, hyperbolic curves were obtained which could be reduced to two…”
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Abnormal Processing of Multiple Proteins in Alzheimer Disease by Zhang, Hong, Sternberger, Nancy H., Rubinstein, Lucien J., Herman, Mary M., Binder, Lester I., Sternberger, Ludwig A.

“…Cerebrovascular amyloid is the main constituent of the perivascular and neuritic plaques typical of Alzheimer disease, whereas neurofilaments and…”
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Phosphorylation of neurofilaments is altered in amyotrophic lateral sclerosis by Manetto, V, Sternberger, N H, Perry, G, Sternberger, L A, Gambetti, P

“…We used a library of monoclonal antibodies (Mab) that distinguish phosphorylated (P+) and non-phosphorylated (P-) neurofilament (NF) epitopes to examine…”
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Phosphorylation protects neurofilaments against proteolysis by Goldstein, M E, Sternberger, N H, Sternberger, L A

“…During incubation with phosphatase, the 200 kDa neurofilament protein in cytoskeletal preparations is degraded extensively. Degradation, which is divalent…”
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Association of synapsin I with neuronal cytoskeleton. Identification in cytoskeletal preparations in vitro and immunocytochemical localization in brain of synapsin I by Goldenring, J R, Lasher, R S, Vallano, M L, Ueda, T, Naito, S, Sternberger, N H, Sternberger, L A, DeLorenzo, R J

“…Calmodulin-dependent protein kinase II (CaM kinase II) is associated with microtubule preparations and phosphorylates several endogenous proteins including…”
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The unlabeled antibody method. Contrasting color staining of paired pituitary hormones without antibody removal by Sternberger, L A, Joseph, S A

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Microheterogeneity (``Neurotypy'') of Neurofilament Proteins by Goldstein, Margi E., Sternberger, Ludwig A., Sternberger, Nancy H.

“…Neurofilaments purified from adult rat brainstem by two methods were electrophoresed on NaDodSO4/polyacrylamide gels to separate the triplet proteins…”
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Expression of neurofilament proteins by Purkinje cells: ultrastructural immunolocalization with monoclonal antibodies by Langley, O K, Sternberger, N H, Sternberger, L A

“…Purkinje cell bodies in rodent cerebellum have been shown to express neurofilament protein epitopes but neurofilaments are rarely seen in these perikarya by…”
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Neurotypy: Regional Individuality in Rat Brain Detected by Immunocytochemistry with Monoclonal Antibodies by Sternberger, Ludwig A., Harwell, Lee W., Sternberger, Nancy H.

“…Hybridomas from spleen cell fusions of six BALB/c mice immunized with hypothalamus were analyzed by immunocytochemistry for antibodies reactive with paraffin…”
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Immunocytochemical studies of neurofilament antigens in the neurofibrillary pathology induced by aluminum by Troncoso, J C, Sternberger, N H, Sternberger, L A, Hoffman, P N, Price, D L

“…Intrathecal administration of aluminum salts induces accumulation of neurofilaments in axons and perikarya of motor neurons and is associated with impaired…”
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Leakage and neuronal uptake of serum protein in aged and Alzheimer brains. A postmortem phenomenon with antemortem etiology by Mori, S, Sternberger, N H, Herman, M M, Sternberger, L A

“…Abnormal extravasation of serum proteins has frequently been reported in Alzheimer's disease (AD) and less often in nondemented, aged individuals. In order to…”
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Cell surface endothelial proteins altered in experimental allergic encephalomyelitis by Sternberger, N H, Sternberger, L A, Kies, M W, Shear, C R

“…Endothelial cells (EC) are increasingly being considered as important participants in the early evolution of inflammatory and immune responses in experimental…”
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Varying degrees of phosphorylation determine microheterogeneity of the heavy neurofilament polypeptide (Nf-H) by Goldstein, M E, Sternberger, L A, Sternberger, N H

“…Two-dimensional immunoblots revealed a spectrum of 200 kDa neurofilament polypeptides (Nf-H) of apparent molecular weights ranging from 200 to 170 kDa. The…”
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Lhermitte-duclos disease: an immunohistochemical study of the cerebellar cortex by SHIURBA, R. A, GESSAGA, E. C, ENG, L. F, STERNBERGER, L. A, STERNBERGER, N. H, URICH, H

“…Immunocytochemical studies were carried out on two previously reported autopsy cases of Lhermitte-Duclos disease. The unaffected cerebellar cortex adjacent to…”
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Immunocytochemical expression of the endothelial barrier antigen (EBA) during brain angiogenesis by Rosenstein, J M, Krum, J M, Sternberger, L A, Pulley, M T, Sternberger, N H

“…The antibody to the endothelial barrier antigen (anti-EBA) is localized to the luminal plasma membrane of endothelia that have a blood-brain barrier (BBB) but…”
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Neurofilamentous abnormalities in motor neurons in spontaneously occurring animal disorders by Cork, L C, Troncoso, J C, Klavano, G G, Johnson, E S, Sternberger, L A, Sternberger, N H, Price, D L

“…Cytoskeletal proteins have a characteristic distribution within neurons when immunocytochemical techniques are used on conventional paraffin sections. For…”
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Neurofilament antigens in acrylamide neuropathy by Gold, B G, Price, D L, Griffin, J W, Rosenfeld, J, Hoffman, P N, Sternberger, N H, Sternberger, L A

“…After repeated exposure, acrylamide (AC) produces degeneration of distal axons. Because neurons whose axons have been injured (e.g. by axotomy) show…”
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