Search Results - "STELLAN, B"

Safety analysis of ex vivo-expanded NK and NK-like T cells administered to cancer patients: a phase I clinical study by Barkholt, Lisbeth, Alici, Evren, Conrad, Reka, Sutlu, Tolga, Gilljam, Mari, Stellan, Birgitta, Christensson, Birger, Guven, Hayrettin, Björkström, Niklas K, Söderdahl, Gunnar, Cederlund, Kerstin, Kimby, Eva, Aschan, Johan, Ringdén, Olle, Ljunggren, Hans-Gustaf, Dilber, M Sirac

“…The chimeric state after allogeneic hematopoietic stem cell transplantation provides a platform for adoptive immunotherapy using donor-derived immune cells…”
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Inhibition of intracellular antiviral defense mechanisms augments lentiviral transduction of human natural killer cells: implications for gene therapy by Sutlu, Tolga, Nyström, Sanna, Gilljam, Mari, Stellan, Birgitta, Applequist, Steven E, Alici, Evren

“…Adoptive immunotherapy with genetically modified natural killer (NK) cells is a promising approach for cancer treatment. Yet, optimization of highly efficient…”
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CD38 Down-Regulation on Ex Vivo Activated and Expanded NK Cells for Cell Therapy Persists after Infusion by Nahi, Hareth, Chrobook, Michael, Meinke, Stephan, Gran, Charlotte, Marquardt, Nicole, Afram, Gabriel, Sutlu, Tolga, Gilljam, Mari, Stellan, Birgitta, Wagner, Arnika Kathleen, Walther-Jallow, Lilian, Liwing, Johan, Klimkowska, Monika, Gahrton, Goesta, Ljungman, Per, Ljunggren, Hans-Gustaf, Alici, Evren

“…Introduction: Immunotherapies are gaining more and more importance in the treatment of multiple myeloma (MM). Antibodies directed against MM antigens like…”
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Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components by Alici, Evren, Sutlu, Tolga, Björkstrand, Bo, Gilljam, Mari, Stellan, Birgitta, Nahi, Hareth, Quezada, Hernan Concha, Gahrton, Gösta, Ljunggren, Hans-Gustaf, Dilber, M. Sirac

“…Multiple myeloma (MM) is an incurable plasma cell malignancy with poor outcome. The most promising therapeutic options currently available are combinations of…”
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Clinical-grade, large-scale, feeder-free expansion of highly active human natural killer cells for adoptive immunotherapy using an automated bioreactor by Sutlu, Tolga, Stellan, Birgitta, Gilljam, Mari, Quezada, Hernan Concha, Nahi, Hareth, Gahrton, Gösta, Alici, Evren

“…Abstract Background aims Natural killer (NK) cell-based adoptive immunotherapy is a promising approach for the treatment of cancer. Ex vivo expansion and…”
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Autologous NK cells as consolidation therapy following stem cell transplantation in multiple myeloma by Nahi, Hareth, Chrobok, Michael, Meinke, Stephan, Gran, Charlotte, Marquardt, Nicole, Afram, Gabriel, Sutlu, Tolga, Gilljam, Mari, Stellan, Birgitta, Wagner, Arnika K., Blomberg, Pontus, Holmqvist, Per-Henrik, Walther-Jallow, Lilian, Mellström, Karin, Liwing, Johan, Gustafsson, Charlotte, Månsson, Robert, Klimkowska, Monika, Gahrton, Gösta, Lund, Johan, Ljungman, Per, Ljunggren, Hans-Gustaf, Alici, Evren

“…Few approaches have been made toward exploring autologous NK cells in settings of cancer immunotherapy. Here, we demonstrate the feasibility of infusing…”
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A FISH cosmid 'cocktail' for detection of 13q deletions in chronic lymphocytic leukaemia : comparison with cytogenetics and Southern hybridization by MERUP, M, JANSSON, M, EINHORN, S, CORCORAN, M, LIU, Y, WU, X, RASOOL, O, STELLAN, B, HERMANSSON, M, JULIUSSON, G, GAHRTON, G

“…The most frequent structural chromosome abnormality in chronic lymphocytic leukaemia (CLL) is deletion at chromosome 13q14. Studies with Southern blot…”
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Functional Assessment for Clinical Use of Serum-Free Adapted NK-92 Cells by Chrobok, Michael, Dahlberg, Carin I M, Sayitoglu, Ece Canan, Beljanski, Vladimir, Nahi, Hareth, Gilljam, Mari, Stellan, Birgitta, Sutlu, Tolga, Duru, Adil Doganay, Alici, Evren

“…Natural killer (NK) cells stand out as promising candidates for cellular immunotherapy due to their capacity to kill malignant cells. However, the therapeutic…”
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Deletion of Chromosomal Region 8p21 Confers Resistance to Bortezomib and Is Associated with Upregulated Decoy TRAIL Receptor Expression in Patients with Multiple Myeloma by Duru, Adil Doganay, Sutlu, Tolga, Wallblom, Ann, Uttervall, Katarina, Lund, Johan, Stellan, Birgitta, Gahrton, Gösta, Nahi, Hareth, Alici, Evren

“…Loss of the chromosomal region 8p21 negatively effects survival in patients with multiple myeloma (MM) that undergo autologous stem cell transplantation…”
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Towards an advanced therapy medicinal product based on mesenchymal stromal cells isolated from the umbilical cord tissue: quality and safety data by Martins, José Paulo, Santos, Jorge Miguel, de Almeida, Joana Marto, Filipe, Mariana Alves, de Almeida, Mariana Vargas Teixeira, Almeida, Sílvia Cristina Paiva, Água-Doce, Ana, Varela, Alexandre, Gilljam, Mari, Stellan, Birgitta, Pohl, Susanne, Dittmar, Kurt, Lindenmaier, Werner, Alici, Evren, Graça, Luís, Cruz, Pedro Estilita, Cruz, Helder Joaquim, Bárcia, Rita Nogueira

“…Standardization of mesenchymal stromal cells (MSCs) manufacturing is urgently needed to enable translational activities and ultimately facilitate comparison of…”
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Adaption of NK-92 cells to serum-free culture with inherent anti-tumor response: NK-92 cells stand strong in a serum-free milieu by Chrobok, M, Dahlberg, CIM, Sayitoglu, C, Nahi, H, Sarhan, D, Gilljam, M, Stellan, B, Sutlu, T, Duru, AD, Alici, E

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Lentiviral‐Mediated HoxB4 Expression in Human Embryonic Stem Cells Initiates Early Hematopoiesis in a Dose‐Dependent Manner but Does Not Promote Myeloid Differentiation by Unger, Christian, Kärner, Elerin, Treschow, Alexandra, Stellan, Birgitta, Felldin, Ulrika, Concha, Hernan, Wendel, Mikael, Hovatta, Outi, Aints, Alar, Ährlund‐Richter, Lars, Dilber, M. Sirac

“…The variation of HoxB4 expression levels might be a key regulatory mechanism in the differentiation of human embryonic stem cell (hESC)‐derived hematopoietic…”
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Multiple Myeloma patients with del(8)(p21) are more resistant to Bortezomib treatment by Duru, AD, Sutlu, T, Wallblom, A, Uttervall, K, Lund, J, Stellan, B, Gahrton, G, Nahi, H, Alici, E

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A Novel Human CCAAT/Enhancer Binding Protein Gene, C/EBPϵ, Is Expressed in Cells of Lymphoid and Myeloid Lineages and Is Localized on Chromosome 14q11.2 Close to the T-Cell Receptor α/δ Locus by Antonson, Per, Stellan, Birgitta, Yamanaka, Ryuya, Xanthopoulos, Kleanthis G.

“…Members of the C/EBP family of transcriptional factors have been implicated in the regulation of genes in a variety of tissues. We report here the isolation…”
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Hairy cell leukemia is characterized by clonal chromosome abnormalities clustered to specific regions by Haglund, U, Juliusson, G, Stellan, B, Gahrton, G

“…Cytogenetic analysis was performed on B-cell mitogen-stimulated cells from 36 patients with symptomatic hairy cell leukemia. Evaluable metaphases were achieved…”
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Molecular Analysis of the Human Chromosome 5q13.3 Region in Patients with Hairy Cell Leukemia and Identification of Tumor Suppressor Gene Candidates by Wu, Xiushan, Ivanova, Ganka, Merup, Mats, Jansson, Monika, Stellan, Birgitta, Grandér, Dan, Zabarovsky, Eugene, Gahrton, Gösta, Einhorn, Stefan

“…The pathogenesis of hairy cell leukemia (HCL) remains largely unknown since no specific genetic lesion has been identified in this disease. Previous…”
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Increased frequency of chromosome abnormalities in fibroblasts from hairy cell leukemia patients by HAGLUND, U, STELLAN, B, JULIUSSON, G, GAHRTON, G

“…A hereditary component is implicated in many different cancers, including hairy cell leukemia (HCL), and may involve an instability of the genome. We have…”
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Amplification of multiple regions of chromosome 12, including 12q13-15, in chronic lymphocytic leukaemia by Merup, Mats, Juliusson, Gunnar, Wu, Xiushan, Jansson, Monika, Stellan, Birgitta, Rasool, Omid, Röijer, Eva, Stenman, Göran, Gahrton, Gösta, Einhorn, Stefan

“…: Trisomy 12 is a frequent abnormality in chronic lymphocytic leukaemia (CLL). The biological importance of trisomy 12 is still poorly understood but it has…”
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A novel human CCAAT/enhancer binding protein gene, C/EBPepsilon, is expressed in cells of lymphoid and myeloid lineages and is localized on chromosome 14q11.2 close to the T-cell receptor alpha/delta locus by Antonson, P, Stellan, B, Yamanaka, R, Xanthopoulos, K G

“…Members of the CsolidusEBP family of transcriptional factors have been implicated in the regulation of genes in a variety of tissues. We report here the…”
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Characterization of a hairy cell leukemia-associated 5q13.3 inversion breakpoint by Wu, Xiushan, Merup, Mats, Juliusson, Gunnar, Jansson, Monika, Stellan, Birgitta, Grandér, Dan, Zabarovsky, Eugene, Liu, Yie, Spasokoukotskaja, Tatiana, Gahrton, Gösta, Einhorn, Stefan

“…Previous cytogenetic analysis has indicated that chromosome anomalies involving the 5q13 band are common in hairy cell leukemia (HCL), occurring in…”
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