Search Results - "STEINFELDT, Heidi M"

Phase I Trial of the Oral Antiangiogenesis Agent AG-013736 in Patients With Advanced Solid Tumors: Pharmacokinetic and Clinical Results by RUGO, Hope S, HERBST, Roy S, LIU, Glenn, PARK, John W, KIES, Merrill S, STEINFELDT, Heidi M, PITHAVALA, Yazdi K, REICH, Steven D, FREDDO, James L, WILDING, George

“…We studied the safety, clinical activity, and pharmacokinetics (PK) of AG-013736, an oral receptor tyrosine kinase inhibitor of vascular endothelial cell…”
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Dynamic Contrast-Enhanced Magnetic Resonance Imaging As a Pharmacodynamic Measure of Response After Acute Dosing of AG-013736, an Oral Angiogenesis Inhibitor, in Patients With Advanced Solid Tumors: Results From a Phase I Study by LIU, Glenn, RUGO, Hope S, CHARNSANGAVEJ, Chusilp, PARK, John W, ASHTON, Edward A, STEINFELDT, Heidi M, PITHAVALA, Yazdi K, REICH, Steven D, HERBST, Roy S, WILDING, George, MCSHANE, Teresa M, EVELHOCH, Jeffrey L, NG, Chaan, JACKSON, Edward, KELCZ, Frederick, YEH, Benjamin M, LEE, Fred T

“…Identifying suitable markers of biologic activity is important when assessing novel compounds such as angiogenesis inhibitors to optimize the dose and schedule…”
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