Search Results - "STEHOUWER, Coen D"

Microvascular Dysfunction and Hyperglycemia: A Vicious Cycle With Widespread Consequences by Stehouwer, Coen D A

“…Microvascular and metabolic physiology are tightly linked. This Perspective reviews evidence that ) the relationship between hyperglycemia and microvascular…”
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Cerebral microvascular complications of type 2 diabetes: stroke, cognitive dysfunction, and depression by van Sloten, Thomas T, Sedaghat, Sanaz, Carnethon, Mercedes R, Launer, Lenore J, Stehouwer, Coen D A

“…Adults with type 2 diabetes are at an increased risk of developing certain brain or mental disorders, including stroke, dementia, and depression. Although…”
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Non-alcoholic fatty liver disease and cardiovascular disease: assessing the evidence for causality by Brouwers, Martijn C. G. J., Simons, Nynke, Stehouwer, Coen D. A., Isaacs, Aaron

“…Non-alcoholic fatty liver disease (NAFLD) is highly prevalent among individuals with type 2 diabetes. Although epidemiological studies have shown that NAFLD is…”
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The Maastricht Study: an extensive phenotyping study on determinants of type 2 diabetes, its complications and its comorbidities by Schram, Miranda T., Sep, Simone J. S., van der Kallen, Carla J., Dagnelie, Pieter C., Koster, Annemarie, Schaper, Nicolaas, Henry, Ronald M. A., Stehouwer, Coen D. A.

“…The Maastricht Study is an extensive phenotyping study that focuses on the etiology of type 2 diabetes (T2DM), its classic complications, and its emerging…”
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Association of Microvascular Dysfunction With Late-Life Depression: A Systematic Review and Meta-analysis by van Agtmaal, Marnix J M, Houben, Alfons J H M, Pouwer, Frans, Stehouwer, Coen D A, Schram, Miranda T

“…The etiologic factors of late-life depression are still poorly understood. Recent evidence suggests that microvascular dysfunction is associated with…”
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Further investigation of the association between diabetes status and body composition and whether this association is moderated by sex. Reply to Mai Y [letter] by de Ritter, Rianneke, Stehouwer, Coen D. A.

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The Link Between Adipose Tissue Renin-Angiotensin-Aldosterone System Signaling and Obesity-Associated Hypertension by Schütten, Monica T J, Houben, Alfons J H M, de Leeuw, Peter W, Stehouwer, Coen D A

“…Obese individuals frequently develop hypertension, which is for an important part attributable to renin-angiotensin-aldosterone system (RAAS) overactivity…”
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Local Stiffness of the Carotid and Femoral Artery Is Associated With Incident Cardiovascular Events and All-Cause Mortality: The Hoorn Study by VAN SLOTEN, Thomas T, SCHRAM, Miranda T, VAN DEN HURK, Katja, DEKKER, Jacqueline M, NIJPELS, Giel, HENRY, Ronald M. A, STEHOUWER, Coen D. A

“…This study sought to investigate the association of local and segmental arterial stiffness with incident cardiovascular events and all-cause mortality. The…”
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Glucose regulation, cognition, and brain MRI in type 2 diabetes: a systematic review by Geijselaers, Stefan L C, MD, Sep, Simone J S, PhD, Stehouwer, Coen D A, Prof, Biessels, Geert Jan, Prof

“…Summary Type 2 diabetes is associated with cognitive dysfunction and structural brain changes. Abnormalities in glucose regulation are involved in several…”
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Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes by Brouwers, Olaf, Niessen, Petra M. G., Miyata, Toshio, Østergaard, Jakob A., Flyvbjerg, Allan, Peutz-Kootstra, Carine J., Sieber, Jonas, Mundel, Peter H., Brownlee, Michael, Janssen, Ben J. A., De Mey, Jo G. R., Stehouwer, Coen D. A., Schalkwijk, Casper G.

“…Aims/hypothesis In diabetes, advanced glycation end-products (AGEs) and the AGE precursor methylglyoxal (MGO) are associated with endothelial dysfunction and…”
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Diabetic retinopathy: looking beyond the eyes by Simó, Rafael, Stehouwer, Coen D. A., Avogaro, Angelo

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The prediabetes conundrum: striking the balance between risk and resources by Blond, Martin B., Færch, Kristine, Herder, Christian, Ziegler, Dan, Stehouwer, Coen D. A.

“…The current definition of prediabetes is controversial and subject to continuous debate. Nonetheless, prediabetes is a risk factor for type 2 diabetes, is…”
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Common Carotid Intima-Media Thickness Measurements in Cardiovascular Risk Prediction: A Meta-analysis by Den Ruijter, Hester M, Peters, Sanne A. E, Anderson, Todd J, Britton, Annie R, Dekker, Jacqueline M, Eijkemans, Marinus J, Engström, Gunnar, Evans, Gregory W, de Graaf, Jacqueline, Grobbee, Diederick E, Hedblad, Bo, Hofman, Albert, Holewijn, Suzanne, Ikeda, Ai, Kavousi, Maryam, Kitagawa, Kazuo, Kitamura, Akihiko, Koffijberg, Hendrik, Lonn, Eva M, Lorenz, Matthias W, Mathiesen, Ellisiv B, Nijpels, Giel, Okazaki, Shuhei, O’Leary, Daniel H, Polak, Joseph F, Price, Jackie F, Robertson, Christine, Rembold, Christopher M, Rosvall, Maria, Rundek, Tatjana, Salonen, Jukka T, Sitzer, Matthias, Stehouwer, Coen D. A, Witteman, Jacqueline C, Moons, Karel G, Bots, Michiel L

“…CONTEXT The evidence that measurement of the common carotid intima-media thickness (CIMT) improves the risk scores in prediction of the absolute risk of…”
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Associations of total amount and patterns of sedentary behaviour with type 2 diabetes and the metabolic syndrome: The Maastricht Study by van der Berg, Julianne D., Stehouwer, Coen D. A., Bosma, Hans, van der Velde, Jeroen H. P. M., Willems, Paul J. B., Savelberg, Hans H. C. M., Schram, Miranda T., Sep, Simone J. S., van der Kallen, Carla J. H., Henry, Ronald M. A., Dagnelie, Pieter C., Schaper, Nicolaas C., Koster, Annemarie

“…Aims/hypothesis The study investigated cross-sectional associations of total amount and patterns of sedentary behaviour with glucose metabolism status and the…”
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Impact of early events and lifestyle on the gut microbiota and metabolic phenotypes in young school-age children by Zhong, Huanzi, Penders, John, Shi, Zhun, Ren, Huahui, Cai, Kaiye, Fang, Chao, Ding, Qiuxia, Thijs, Carel, Blaak, Ellen E, Stehouwer, Coen D A, Xu, Xun, Yang, Huanming, Wang, Jian, Wang, Jun, Jonkers, Daisy M A E, Masclee, Ad A M, Brix, Susanne, Li, Junhua, Arts, Ilja C W, Kristiansen, Karsten

“…The gut microbiota evolves from birth and is in early life influenced by events such as birth mode, type of infant feeding, and maternal and infant antibiotics…”
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Adapted dietary inflammatory index and its association with a summary score for low-grade inflammation and markers of glucose metabolism: the Cohort study on Diabetes and Atherosclerosis Maastricht (CODAM) and the Hoorn study by van Woudenbergh, Geertruida J, Theofylaktopoulou, Despoina, Kuijsten, Anneleen, Ferreira, Isabel, van Greevenbroek, Marleen M, van der Kallen, Carla J, Schalkwijk, Casper G, Stehouwer, Coen DA, Ocké, Marga C, Nijpels, Giel, Dekker, Jacqueline M, Blaak, Ellen E, Feskens, Edith JM

“…Background: Diet may be associated with the development of type 2 diabetes through its effects on low-grade inflammation.Objectives: We investigated whether an…”
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Treatment of Hypertension in the Oldest Old: A Critical Role for Frailty? by Muller, Majon, Smulders, Yvo M., de Leeuw, Peter W., Stehouwer, Coen D.A.

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Effect of Moderate-Intensity Exercise Versus Activities of Daily Living on 24-Hour Blood Glucose Homeostasis in Male Patients With Type 2 Diabetes by VAN DIJK, Jan-Willem, VENEMA, Maarten, VAN MECHELEN, Willem, STEHOUWER, Coen D. A, HARTGENS, Fred, VAN LOON, Luc J. C

“…To investigate the impact of activities of daily living (ADL) versus moderate-intensity endurance-type exercise on 24-h glycemic control in patients with type…”
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Vascular complications in diabetes mellitus: the role of endothelial dysfunction by Schalkwijk, Casper G, Stehouwer, Coen D A

“…The endothelium is a complex organ with a multitude of properties essential for control of vascular functions. Dysfunction of the vascular endothelium is…”
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Sedentary behaviour and physical activity are associated with biomarkers of endothelial dysfunction and low-grade inflammation—relevance for (pre)diabetes: The Maastricht Study by Vandercappellen, Evelien J., Koster, Annemarie, Savelberg, Hans H. C. M., Eussen, Simone J. P. M., Dagnelie, Pieter C., Schaper, Nicolaas C., Schram, Miranda T., van der Kallen, Carla J. H., van Greevenbroek, Marleen M. J., Wesselius, Anke, Schalkwijk, Casper G., Kroon, Abraham A., Henry, Ronald M. A., Stehouwer, Coen D. A.

“…Aims/hypothesis Biomarkers of endothelial dysfunction and low-grade inflammation are important in the pathogenesis of CVD and can potentially be modified by…”
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