Search Results - "STEFANIS, Nikos C"

Don't blame psychosis, blame the lack of services: a message for early intervention from the Greek standard care model by Dimitrakopoulos, Stefanos, Stefanatou, Pentagiotissa, Vlachos, Ilias, Selakovic, Mirjana, Xenaki, Lida-Alkisti, Ralli, Irene, Soldatos, Rigas-Filippos, Nianiakas, Nikolaos, Kosteletos, Ioannis, Foteli, Stefania, Mantonakis, Leonidas, Kollias, Costas T, Stefanis, Nikos C

“…Early Intervention Services (EIS) aim to reduce relapse rates and achieve better treatment and functional outcomes for first episode psychosis (FEP) patients…”
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Diminished social motivation in early psychosis is associated with polygenic liability for low vitamin D by Hatzimanolis, Alex, Tosato, Sarah, Ruggeri, Mirella, Cristofalo, Doriana, Mantonakis, Leonidas, Xenaki, Lida-Alkisti, Dimitrakopoulos, Stefanos, Selakovic, Mirjana, Foteli, Stefania, Kosteletos, Ioannis, Vlachos, Ilias, Soldatos, Rigas-Filippos, Nianiakas, Nikos, Ralli, Irene, Kollias, Konstantinos, Ntigrintaki, Angeliki-Aikaterini, Stefanatou, Pentagiotissa, Murray, Robin M., Vassos, Evangelos, Stefanis, Nikos C.

“…Insufficiency of vitamin D levels often occur in individuals with schizophrenia and first-episode psychosis (FEP). However, it is unknown whether this…”
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Cognitive Inflexibility Predicts Negative Symptoms Severity in Patients with First-Episode Psychosis: A 1-Year Follow-Up Study by Mantonakis, Leonidas, Stefanatou, Pentagiotissa, Tsionis, Antonis, Konstantakopoulos, George, Xenaki, Lida-Alkisti, Ntigrintaki, Angeliki-Aikaterini, Ralli, Irene, Dimitrakopoulos, Stefanos, Kollias, Konstantinos, Stefanis, Nikos C

“…Negative symptoms and cognitive deficits play a major role in psychosis and significantly influence the functional outcomes of patients, particularly those…”
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Role of Clinical Insight at First Month in Predicting Relapse at the Year in First Episode of Psychosis (FEP) Patients by Vlachos, Ilias I, Selakovic, Mirjana, Ralli, Irene, Hatzimanolis, Alexandros, Xenaki, Lida-Alkisti, Dimitrakopoulos, Stefanos, Soldatos, Rigas-Filippos, Foteli, Stefania, Nianiakas, Nikos, Kosteletos, Ioannis, Stefanatou, Pentagiotissa, Ntigrintaki, Angeliki-Aikaterini, Triantafyllou, Theoni-Fani, Voulgaraki, Marina, Ermiliou, Vassiliki, Mantonakis, Leonidas, Kollias, Konstantinos, Stefanis, Nikos C

“…Clinical insight constitutes a useful marker of the progress and outcome of the First Episode of Psychosis (FEP), and lack of insight has been associated with…”
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Does accumulating exposure to illicit drugs bring forward the age at onset in schizophrenia? by Power, Brian D, Dragovic, Milan, Jablensky, Assen, Stefanis, Nikos C

“…Objective: Whilst cannabis has been associated with an earlier age at onset in schizophrenia, the impact of amphetamine and/or cocaine plus cannabis…”
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Screening Human Embryos for Polygenic Traits Has Limited Utility by Karavani, Ehud, Zuk, Or, Zeevi, Danny, Barzilai, Nir, Stefanis, Nikos C., Hatzimanolis, Alex, Smyrnis, Nikolaos, Avramopoulos, Dimitrios, Kruglyak, Leonid, Atzmon, Gil, Lam, Max, Lencz, Todd, Carmi, Shai

“…The increasing proportion of variance in human complex traits explained by polygenic scores, along with progress in preimplantation genetic diagnosis, suggests…”
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Deregulation of complement components C4A and CSMD1 peripheral expression in first-episode psychosis and links to cognitive ability by Hatzimanolis, Alex, Foteli, Stefania, Stefanatou, Pentagiotissa, Ntigrintaki, Angeliki-Aikaterini, Ralli, Irene, Kollias, Konstantinos, Nikolaou, Chrysoula, Gazouli, Maria, Stefanis, Nikos C.

“…Up-regulation of the complement component 4A (C4A) in the brain has been associated with excessive synaptic pruning and increased schizophrenia (SZ)…”
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Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways by Lam, Max, Hill, W. David, Trampush, Joey W., Yu, Jin, Knowles, Emma, Davies, Gail, Stahl, Eli, Huckins, Laura, Liewald, David C., Djurovic, Srdjan, Melle, Ingrid, Sundet, Kjetil, Christoforou, Andrea, Reinvang, Ivar, DeRosse, Pamela, Lundervold, Astri J., Steen, Vidar M., Espeseth, Thomas, Räikkönen, Katri, Widen, Elisabeth, Palotie, Aarno, Eriksson, Johan G., Giegling, Ina, Konte, Bettina, Hartmann, Annette M., Roussos, Panos, Giakoumaki, Stella, Burdick, Katherine E., Payton, Antony, Ollier, William, Chiba-Falek, Ornit, Attix, Deborah K., Need, Anna C., Cirulli, Elizabeth T., Voineskos, Aristotle N., Stefanis, Nikos C., Avramopoulos, Dimitrios, Hatzimanolis, Alex, Arking, Dan E., Smyrnis, Nikolaos, Bilder, Robert M., Freimer, Nelson A., Cannon, Tyrone D., London, Edythe, Poldrack, Russell A., Sabb, Fred W., Congdon, Eliza, Conley, Emily Drabant, Scult, Matthew A., Dickinson, Dwight, Straub, Richard E., Donohoe, Gary, Morris, Derek, Corvin, Aiden, Gill, Michael, Hariri, Ahmad R., Weinberger, Daniel R., Pendleton, Neil, Bitsios, Panos, Rujescu, Dan, Lahti, Jari, Le Hellard, Stephanie, Keller, Matthew C., Andreassen, Ole A., Deary, Ian J., Glahn, David C., Malhotra, Anil K., Lencz, Todd

“…Susceptibility to schizophrenia is inversely correlated with general cognitive ability at both the phenotypic and the genetic level. Paradoxically, a modest…”
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Age at Initiation of Cannabis Use Predicts Age at Onset of Psychosis: The 7- to 8-Year Trend by STEFANIS, Nikos C, DRAGOVIC, Milan, POWER, Brian D, JABLENSKY, Assen, CASTLE, David, MORGAN, Vera Anne

“…We investigated the existence of a temporal association between age at initiation of cannabis use and age at onset of psychotic illness in 997 participants…”
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Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets by Lam, Max, Trampush, Joey W., Yu, Jin, Knowles, Emma, Davies, Gail, Liewald, David C., Starr, John M., Djurovic, Srdjan, Melle, Ingrid, Sundet, Kjetil, Christoforou, Andrea, Reinvang, Ivar, DeRosse, Pamela, Lundervold, Astri J., Steen, Vidar M., Espeseth, Thomas, Räikkönen, Katri, Widen, Elisabeth, Palotie, Aarno, Eriksson, Johan G., Giegling, Ina, Konte, Bettina, Roussos, Panos, Giakoumaki, Stella, Burdick, Katherine E., Payton, Antony, Ollier, William, Chiba-Falek, Ornit, Attix, Deborah K., Need, Anna C., Cirulli, Elizabeth T., Voineskos, Aristotle N., Stefanis, Nikos C., Avramopoulos, Dimitrios, Hatzimanolis, Alex, Arking, Dan E., Smyrnis, Nikolaos, Bilder, Robert M., Freimer, Nelson A., Cannon, Tyrone D., London, Edythe, Poldrack, Russell A., Sabb, Fred W., Congdon, Eliza, Conley, Emily Drabant, Scult, Matthew A., Dickinson, Dwight, Straub, Richard E., Donohoe, Gary, Morris, Derek, Corvin, Aiden, Gill, Michael, Hariri, Ahmad R., Weinberger, Daniel R., Pendleton, Neil, Bitsios, Panos, Rujescu, Dan, Lahti, Jari, Le Hellard, Stephanie, Keller, Matthew C., Andreassen, Ole A., Deary, Ian J., Glahn, David C., Malhotra, Anil K., Lencz, Todd

“…Here, we present a large (n = 107,207) genome-wide association study (GWAS) of general cognitive ability (“g”), further enhanced by combining results with a…”
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Association of Alcohol Use Disorder Risk With ADH1B, DRD2, FAAH, SLC39A8, GCKR , and PDYN Genetic Polymorphisms by LEGAKI, EVANGELIA, TSAKLAKIDOU, DOMNA, HATZIMANOLIS, ALEX, SEGREDOU, EIRINI, PETALOTIS, MARKOS, MOULAROGIORGOU, GIANNOULA, MOUCHTOURI, VARVARA, LYKOURAS, LEFTERIS, STEFANIS, NIKOS C., GAZOULI, MARIA

“…BACKGROUND/AIMAlcohol use disorder (AUD) is a chronic, multifactorial psychiatric condition with an enormous impact on public health and social cost. Genetic…”
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The relationship between early symptom severity, improvement and remission in first episode psychosis with jumping to conclusions by Xenaki, Lida Alkisti, Stefanatou, Pentagiotissa, Ralli, Eirini, Hatzimanolis, Alex, Dimitrakopoulos, Stefanos, Soldatos, Rigas Filippos, Vlachos, Ilias I., Selakovic, Mirjana, Foteli, Stefania, Kosteletos, Ioannis, Nianiakas, Nikos, Ntigridaki, Aggeliki, Triantafyllou, Theoni - Fani, Voulgaraki, Marina, Mantonakis, Leonidas, Tsapas, Apostolos, Bozikas, Vasilios P., Kollias, Konstantinos, Stefanis, Nikos C.

“…It is suggested that Jumping To Conclusions (JTC) reasoning bias might contribute to the distortion of external reality. However, the association between…”
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Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics by Lam, Max, Chen, Chia-Yen, Ge, Tian, Xia, Yan, Hill, David W, Trampush, Joey W, Yu, Jin, Knowles, Emma, Davies, Gail, Stahl, Eli A, Huckins, Laura, Liewald, David C, Djurovic, Srdjan, Melle, Ingrid, Christoforou, Andrea, Reinvang, Ivar, DeRosse, Pamela, Lundervold, Astri J, Steen, Vidar M, Espeseth, Thomas, Räikkönen, Katri, Widen, Elisabeth, Palotie, Aarno, Eriksson, Johan G, Giegling, Ina, Konte, Bettina, Hartmann, Annette M, Roussos, Panos, Giakoumaki, Stella, Burdick, Katherine E, Payton, Antony, Ollier, William, Chiba-Falek, Ornit, Koltai, Deborah C, Need, Anna C, Cirulli, Elizabeth T, Voineskos, Aristotle N, Stefanis, Nikos C, Avramopoulos, Dimitrios, Hatzimanolis, Alex, Smyrnis, Nikolaos, Bilder, Robert M, Freimer, Nelson B, Cannon, Tyrone D, London, Edythe, Poldrack, Russell A, Sabb, Fred W, Congdon, Eliza, Conley, Emily Drabant, Scult, Matthew A, Dickinson, Dwight, Straub, Richard E, Donohoe, Gary, Morris, Derek, Corvin, Aiden, Gill, Michael, Hariri, Ahmad R, Weinberger, Daniel R, Pendleton, Neil, Bitsios, Panos, Rujescu, Dan, Lahti, Jari, Le Hellard, Stephanie, Keller, Matthew C, Andreassen, Ole A, Deary, Ian J, Glahn, David C, Huang, Hailiang, Liu, Chunyu, Malhotra, Anil K, Lencz, Todd

“…Broad-based cognitive deficits are an enduring and disabling symptom for many patients with severe mental illness, and these impairments are inadequately…”
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The effect of drug use on the age at onset of psychotic disorders in an Australian cohort by Stefanis, Nikos C, Dragovic, Milan, Power, Brian D, Jablensky, Assen, Castle, David, Morgan, Vera A

“…Abstract Background We aimed to examine the association between illicit substance use and age at onset in psychotic disorders in an Australian cohort. Methods…”
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Age at initiation of amphetamine use and age at onset of psychosis: The Australian Survey of High Impact Psychosis by Power, Brian D, Stefanis, Nikos C, Dragovic, Milan, Jablensky, Assen, Castle, David, Morgan, Vera

“…Abstract Individuals with a psychotic disorder who had a premorbid history of amphetamine use ( n = 382) were analyzed in groups according to age of initiation…”
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A Missense Variant in CASKIN1's Proline-Rich Region Segregates with Psychosis in a Three-Generation Family by Wahbeh, Marah H, Peng, Xi, Bacharaki, Sofia, Hatzimanolis, Alexandros, Dimitrakopoulos, Stefanos, Wohler, Elizabeth, Yang, Xue, Yovo, Christian, Maher, Brady J, Sobreira, Nara, Stefanis, Nikos C, Avramopoulos, Dimitrios

“…The polygenic nature of schizophrenia (SCZ) implicates many variants in disease development. Rare variants of high penetrance have been shown to contribute to…”
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The role of serotonergic genes and environmental stress on the development of depressive symptoms and neuroticism by Mandelli, Laura, Antypa, Niki, Nearchou, Finiki A, Vaiopoulos, Chrysostomos, Stefanis, Costas N, Serretti, Alessandro, Stefanis, Nikos C

“…Abstract Background Depression is considered to be the result of a complicated synergy between genetic and environmental factors. Several genes of the…”
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No additive effect of cannabis on cognition in schizophrenia by Power, Brian D, Dragovic, Milan, Badcock, Johanna C, Morgan, Vera A, Castle, David, Jablensky, Assen, Stefanis, Nikos C

“…Abstract Background We aimed to examine the association between lifetime cannabis use and estimates of both premorbid and current cognitive function in…”
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Organization framework and preliminary findings from the Athens First‐Episode Psychosis Research Study by Xenaki, Lida‐Alkisti, Kollias, Costas T., Stefanatou, Pentagiotissa, Ralli, Irene, Soldatos, Rigas‐Filippos, Dimitrakopoulos, Stefanos, Hatzimanolis, Alex, Triantafyllou, Theoni‐Fani, Kosteletos, Ioannis, Vlachos, Ilias I., Selakovic, Mirjana, Foteli, Stefania, Mantonakis, Leonidas, Ermiliou, Vassiliki, Voulgaraki, Marina, Psarra, Evagelia, Gülöksüz, Sinan, Os, Jim, Stefanis, Nikos C.

“…Aims Athens First‐Episode Psychosis (FEP) Research study, aims to explore the potential associations between multiple genetic, environmental and neurometabolic…”
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The 3111T/C polymorphism interacts with stressful life events to influence patterns of sleep in females by Antypa, Niki, Mandelli, Laura, Nearchou, Finiki A, Vaiopoulos, Chrysostomos, Stefanis, Costas N, Serretti, Alessandro, Stefanis, Nikos C

“…Genetic variations in clock-relevant genes have been investigated in relation to sleep abnormalities, both in healthy populations and in mood-disorder patients…”
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