Search Results - "STEEL, D. M"

Neutralization of pH in the Golgi apparatus causes redistribution of glycosyltransferases and changes in the O-glycosylation of mucins by Axelsson, M A, Karlsson, N G, Steel, D M, Ouwendijk, J, Nilsson, T, Hansson, G C

“…Addition of the weak base ammonium chloride (NH4Cl) or the proton pump inhibitor bafilomycin A1 to cultured HeLa and LS 174T cells effectively neutralized the…”
Get full text

In vitro real-time characterization of cell attachment and spreading by Fredriksson, C, Khilman, S, Kasemo, B, Steel, D M

“…A method based on the piezoelectric quartz crystal microbalance (QCM) technique for in vitro real-time characterization of cell attachment and spreading on…”
Get full text

Identification of novel members of the serum amyloid A protein superfamily as constitutive apolipoproteins of high density lipoprotein by WHITEHEAD, A. S, DE BEER, M. C, STEEL, D. M, RITS, M, LELIAS, J. M, LANE, W. S, DE BEER, F. C

“…A novel serum amyloid A protein (SAA) has been identified as a normal apolipoprotein component of non-acute phase high density lipoprotein. This novel SAA has…”
Get full text

Non-invasive liposome-mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice by Alton, E. W. F. W, Middleton, P. G, Caplen, N. J, Smith, S. N, Steel, D. M, Munkonge, F. M, Jeffery, P. K, Geddes, D. M, Hart, S. L, Williamson, R, Fasold, K. I, Miller, A. D, Dickinson, P, Stevenson, B. J, McLachlan, G, Dorin, J. R, Porteous, D. J

Get full text

Muscarinic-induced mucin secretion and intracellular signaling by hamster tracheal goblet cells by Steel, D M, Hanrahan, J W

“…Hamster tracheal epithelial cell cultures were used to investigate muscarinic regulation of high-molecular-weight glycoconjugate (HMWG) secretion by airway…”
Get full text

Bioelectric characteristics of exon 10 insertional cystic fibrosis mouse: comparison with humans by Smith, S N, Steel, D M, Middleton, P G, Munkonge, F M, Geddes, D M, Caplen, N J, Porteous, D J, Dorin, J R, Alton, E W

“…Two important issues that can be addressed by animal models are disease pathogenesis and the testing of new treatments, including gene therapy. How closely…”
Get full text

Expression and regulation of constitutive and acute phase serum amyloid A mRNAs in hepatic and non-hepatic cell lines by Steel, D M, Donoghue, F C, O'Neill, R M, Uhlar, C M, Whitehead, A S

“…'Acute phase' and 'constitutive' SAA (A-SAA and C-SAA, respectively) mRNA levels were measured in hepatic and non-hepatic cell lines after treatment with…”
Get more information

Second-messenger regulation of sodium transport in mammalian airway epithelia by Graham, A, Steel, D M, Alton, E W, Geddes, D M

“…1. Sodium absorption is the dominant ion transport process in conducting airways and is a major factor regulating the composition of airway surface liquid…”
Get full text

The effect of antisense RNA to fibronectin on the malignancy of hybrids between melanoma cells and normal fibroblasts by STEEL, D. M, HARRIS, H

“…An expression vector containing a cDNA complementary to 1.3 kb of the 5' coding sequences of the fibronectin gene in the antisense orientation with respect to…”
Get full text

A constitutively expressed serum amyloid A protein gene (SAA4) is closely linked to, and shares structural similarities with, an acute-phase serum amyloid A protein gene (SAA2) by Steel, D M, Sellar, G C, Uhlar, C M, Simon, S, DeBeer, F C, Whitehead, A S

“…The acute-phase reactant serum amyloid A (SAA) is a polymorphic apolipoprotein encoded by a family of highly homologous and closely linked genes: SAA1, SAA2,…”
Get more information

Effects of purified Pseudomonas rhamnolipids on bioelectric properties of sheep tracheal epithelium by Graham, A, Steel, D M, Wilson, R, Cole, P J, Alton, E W, Geddes, D M

“…The effects of purified rhamnolipids from Pseudomonas aeruginosa on short circuit current in respiratory epithelium have been studied in sheep tracheal…”
Get more information

The major acute phase reactants: C-reactive protein, serum amyloid P component and serum amyloid A protein by Steel, D M, Whitehead, A S

“…Following an acute phase stimulus, such as infection or physical injury, many liver-derived plasma proteins are increased in concentration. These provide…”
Get more information

Amyloid resistance in A J mice is not determined by genetic variants at, or close to, serum amyloid P component locus by WHITEHEAD, A. S, GONNERMAN, W, STEEL, D. M, ZAHEDI, K

“…An experimental model to assess the utility of variants of the serum amyloid P component (SAP) gene in predicting resistance to amyloidosis resulting from…”
Get full text

Characterization and comparison of ion transport across sheep and human airway epithelium by Steel, D M, Graham, A, Geddes, D M, Alton, E W

“…This study aimed to assess the suitability of sheep tracheal epithelium as a model for studies of human airway ion transport. Ovine and human airway epithelium…”
Get more information

Biosynthesis of human acute-phase serum amyloid A protein (A-SAA) in vitro: the roles of mRNA accumulation, poly(A) tail shortening and translational efficiency by Steel, D M, Rogers, J T, DeBeer, M C, DeBeer, F C, Whitehead, A S

“…Human 'acute-phase' serum amyloid A protein (A-SAA) is a major acute-phase reactant (APR) and an apolipoprotein of high density lipoprotein 3 (HDL3). We have…”
Get full text

Posttranscriptional Regulation of Acute Phase Serum Amyloid A2 Expression by the 5'- and 3'-Untranslated Regions of Its mRNA by Longley, Daniel B, Steel, Diana M, Whitehead, Alexander S

“…Human acute-phase serum amyloid A protein (A-SAA) is a major acute phase reactant, the concentration of which increases dramatically as part of the body's…”
Get full text

Use of the acute phase serum amyloid A2 ( SAA2) gene promoter in the analysis of pro- and anti-inflammatory mediators: differential kinetics of SAA2 promoter induction by IL-1 β and TNF- α compared to IL-6 by Uhlar, Clarissa M, Grehan, Sharon, Steel, Diana M, Steinkasserer, Alexander, Whitehead, Alexander S

“…A cytokine responsive construct, pGL2-SAA2pt, was generated by cloning the acute phase promoter of human serum amyloid A2 ( SAA2) upstream of a luciferase…”
Get full text

Nucleotide sequence and expression of the human gene encoding apolipoprotein H (beta 2-glycoprotein I) by Mehdi, H, Nunn, M, Steel, D M, Whitehead, A S, Perez, M, Walker, L, Peeples, M E

“…Human apolipoprotein H (ApoH), also called beta 2-glycoprotein I, is a 50-kDa serum glycoprotein whose function is not clearly defined. We have cloned and…”
Get more information

Heterogeneous modulation of acute-phase-reactant mRNA levels by interleukin-1β and interleukin-6 in the human hepatoma cell line PLC/PRF/5 by STEEL, D. M, WHITEHEAD, A. S

“…The acute-phase response to tissue injury and inflammation is accompanied by a dramatic increase in the hepatic synthesis of plasma proteins known as…”
Get full text

A case of hyperfunctioning pancreatic mixed adenoneuroendocrine carcinoma (MANEC) arising from ectopic pancreatic tissue in the liver by Steel, Christopher J., MD, Hostetler, Valerie, MD, Dunn, Dell, MD

“…Abstract We report the case of a hyperfunctioning mixed adenoneuroendocrine carcinoma (MANEC) arising from ectopic pancreatic tissue in the liver. To our…”
Get full text