Search Results - "STECKER, Kim"

Chemically modified oligonucleotides exhibit decreased immune stimulation in mice by Henry, S, Stecker, K, Brooks, D, Monteith, D, Conklin, B, Bennett, C F

“…Phosphorothioate oligodeoxynucleotides produce splenomegaly and mononuclear cell infiltrates in multiple organs in mice after repeated i.v. administration…”
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An ICAM-1 antisense oligonucleotide prevents and reverses dextran sulfate sodium-induced colitis in mice by Bennett, C F, Kornbrust, D, Henry, S, Stecker, K, Howard, R, Cooper, S, Dutson, S, Hall, W, Jacoby, H I

“…Mice treated p.o. with 5% dextran sodium sulfate develop a mild to moderate colitis characterized by focal areas of inflammation and crypt abscesses…”
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Characterization of a hyaluronic acid-Arg-Gly-Asp peptide cell attachment matrix by Glass, James R., Dickerson, Ken T., Stecker, Kim, Polarek, James W.

“…We have developed a method to modify cross-linked hyaluronic acid with peptides containing the Arg-Gly-Asp sequence. The material created by this process is a…”
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In vivo distribution and metabolism of a phosphorothioate oligonucleotide within rat liver after intravenous administration by Graham, M J, Crooke, S T, Monteith, D K, Cooper, S R, Lemonidis, K M, Stecker, K K, Martin, M J, Crooke, R M

“…In the rat, the liver represents a major site of phosphorothioate oligodeoxynucleotide deposition after i.v. administration. For this reason, we examined the…”
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ICAM-1 antisense oligodeoxynucleotide improves islet allograft survival and function by Katz, S M, Bennett, F, Stecker, K, Clark, J H, Pham, T, Wang, M E, Kahan, B D, Stepkowski, S M

“…Expression of intercellular adhesion molecule-1 (ICAM-1) and its ligand, leukocyte function antigen-1 (LFA-1), after pancreatic islet transplantation may…”
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Cellular distribution of phosphorothioate oligodeoxynucleotides in normal rodent tissues by Butler, M, Stecker, K, Bennett, C F

“…The distribution of intravenously injected phosphorothioate oligodeoxynucleotides (P = S ODN) was studied in vivo in rodent tissues using three histologic…”
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Protection against allograft rejection with intercellular adhesion molecule-1 antisense oligodeoxynucleotides by STEPKOWSKI, S. M, WANG, M.-E, BENNETT, C. F, CONDON, T. P, CHENG-FLOURNOY, S, STECKER, K, GRAHAM, M, XIUMEI QU, LING TIAN, WENHAO CHEN, KAHAN, B. D

“…We designed an antisense phosphorothioate oligodeoxynucleotide (oligo) to specifically inhibit the expression of rat intercellular adhesion molecule-1 (ICAM-1)…”
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Methoxyethyl-modified intercellular adhesion molecule-1 antisense phosphorothiateoligonucleotides inhibit allograft rejection, ischemic-reperfusion injury, and cyclosporine-induced nephrotoxicity by WENHAU CHEN, LANGER, Robert M, BENNETT, C. Frank, STEPKOWSKI, Stanislaw M, JANCZEWSKA, Slawa, FURIAN, Lucrezia, GEARY, Richard, XUIMEI QU, WANG, Mouer, VERANI, Regina, CONDON, Tom, STECKER, Kim

“…The addition of phosphorothioate (PS) groups to natural phosphodiester (PD) antisense oligodeoxynucleotides (oligo) prevents their in vivo hydrolysis by…”
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Intravitreous anti-raf-1 kinase antisense oligonucleotide as an angioinhibitory agent in porcine preretinal neovascularization by Danis, Ronald P., Criswell, Mark H., Orge, Faruk, Wancewicz, Edward V., Stecker, Kim, Henry, Scott P., Monia, Brett P.

“…Purpose. To test the efficacy of a synthetic antisense oligonucleotide inhibitor of an intracellular signal transduction protein, C-raf-1 kinase, as an…”
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PERFUSION OF KIDNEYS WITH UNFORMULATED "NAKED" INTERCELLULAR ADHESION MOLECULE-1 ANTISENSE OLIGODEOXYNUCLEOTIDES PREVENTS ISCHEMIC/REPERFUSION INJURY1 by Chen, Wenhau, Bennett, C. Frank, Wang, Mou-Er, Dragun, Duska, Tian, Ling, Stecker, Kim, Clark, James H., Kahan, Barry D., Stepkowski, Stanislaw M.

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INTERCELLULAR ADHESION MOLECULE-1 ANTISENSE OLIGODEOXYNUCLEOTIDES REDUCES HEPATIC ISCHEMIA/ REPERFUSION INJURY: Abstract# 737 by Ghobrial, Rafik M., Amersi, Farin F., Stecker, Kim, Kato, Hirohisa, Melinek, Judy, Singer, Jeniffer S., Mhoyan, Anna, Zhao, Danyun, Busuttil, Ronald W., Kupiec-Weglinski, Jerzy W., Stepkowski, Stanislaw M.

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PROTECTION AGAINST ALLOGRAFT REJECTION WITH INTERCELLULAR ADHESION MOLECULE-1 ANTISENSE OLIGODEOXYNUCLEOTIDES1 by Stepkowski, Stanislaw M., Wang, Mou-er, Condon, Thomas P., Cheng-Fluornoy, Shin, Stecker, Kim, Graham, Mark, Qu, Xiumei, Tian, Ling, Chen, Wenhao, Kahan, Barry D., Bennett, C. Frank

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