Search Results - "STAVROPOULOU, Alexandra V"

Transcriptional Cross Talk between the Forkhead Transcription Factor Forkhead Box O1A and the Progesterone Receptor Coordinates Cell Cycle Regulation and Differentiation in Human Endometrial Stromal Cells by Takano, Masashi, Lu, Zhenxiao, Goto, Tomoko, Fusi, Luca, Higham, Jenny, Francis, Julia, Withey, Anna, Hardt, Jennifer, Cloke, Brianna, Stavropoulou, Alexandra V, Ishihara, Osamu, Lam, Eric W.-F, Unterman, Terry G, Brosens, Jan J, Kim, J. Julie

“…Differentiation of human endometrial stromal cells (HESCs) into decidual cells is associated with induction of the forkhead transcription factor forkhead box…”
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Prevalence of BRCA1 mutations in familial and sporadic greek ovarian cancer cases by Stavropoulou, Alexandra V, Fostira, Florentia, Pertesi, Maroulio, Tsitlaidou, Marianthi, Voutsinas, Gerassimos E, Triantafyllidou, Olga, Bamias, Aristotelis, Dimopoulos, Meletios A, Timotheadou, Eleni, Pectasides, Dimitrios, Christodoulou, Christos, Klouvas, George, Papadimitriou, Christos, Makatsoris, Thomas, Pentheroudakis, George, Aravantinos, Gerasimos, Karydakis, Vassilis, Yannoukakos, Drakoulis, Fountzilas, George, Konstantopoulou, Irene

“…Germline mutations in the BRCA1 and BRCA2 genes contribute to approximately 18% of hereditary ovarian cancers conferring an estimated lifetime risk from 15% to…”
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Histone Deacetylase Inhibitor Trichostatin A Represses Estrogen Receptor α-Dependent Transcription and Promotes Proteasomal Degradation of Cyclin D1 in Human Breast Carcinoma Cell Lines by ALAO, John Patrick, LAM, Eric W.-F, ALI, Simak, BULUWELA, Laki, BORDOGNA, Walter, LOCKEY, Peter, VARSHOCHI, Rana, STAVROPOULOU, Alexandra V, COOMBES, R. Charles, VIGUSHIN, David M

“…Purpose: Estrogen receptor α (ERα)-positive breast cancer cell lines are up to 10 times more sensitive than ERα-negative cell lines to the antiproliferative…”
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An integrated bacterial system for the discovery of chemical rescuers of disease-associated protein misfolding by Matis, Ilias, Delivoria, Dafni Chrysanthi, Mavroidi, Barbara, Papaevgeniou, Nikoletta, Panoutsou, Stefania, Bellou, Stamatia, Papavasileiou, Konstantinos D., Linardaki, Zacharoula I., Stavropoulou, Alexandra V., Vekrellis, Kostas, Boukos, Nikos, Kolisis, Fragiskos N., Gonos, Efstathios S., Margarity, Marigoula, Papadopoulos, Manthos G., Efthimiopoulos, Spiros, Pelecanou, Maria, Chondrogianni, Niki, Skretas, Georgios

“…Protein misfolding and aggregation are common pathological features of several human diseases, including Alzheimer’s disease and type 2 diabetes. Here, we…”
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Histone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells by Alao, John P, Stavropoulou, Alexandra V, Lam, Eric W-F, Coombes, R Charles, Vigushin, David M

“…Cyclin D1 is an important regulator of G1-S phase cell cycle transition and has been shown to be important for breast cancer development. GSK3beta…”
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Role of glycogen synthase kinase 3 beta (GSK3beta) in mediating the cytotoxic effects of the histone deacetylase inhibitor trichostatin A (TSA) in MCF-7 breast cancer cells by Alao, John P, Stavropoulou, Alexandra V, Lam, Eric W-F, Coombes, R Charles

“…Histone deacetylase inhibitors (HDACIs) have been shown to induce apoptotic and autophagic cell death in vitro and in vivo. The molecular mechanisms that…”
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The cyclin D1 proto-oncogene is sequestered in the cytoplasm of mammalian cancer cell lines by Alao, John P, Gamble, Simon C, Stavropoulou, Alexandra V, Pomeranz, Karen M, Lam, Eric W-F, Coombes, R Charles, Vigushin, David M

“…The cyclin D1 proto-oncogene is an important regulator of G1 to S-phase transition and an important cofactor for several transcription factors in numerous cell…”
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Prevalence of BRCA1 mutations among 403 women with triple-negative breast cancer: implications for genetic screening selection criteria: a Hellenic Cooperative Oncology Group Study by Fostira, Florentia, Tsitlaidou, Marianthi, Papadimitriou, Christos, Pertesi, Maroulio, Timotheadou, Eleni, Stavropoulou, Alexandra V., Glentis, Stavros, Bournakis, Evangelos, Bobos, Mattheos, Pectasides, Dimitrios, Papakostas, Pavlos, Pentheroudakis, George, Gogas, Helen, Skarlos, Pantelis, Samantas, Epaminontas, Bafaloukos, Dimitrios, Kosmidis, Paris A., Koutras, Angelos, Yannoukakos, Drakoulis, Konstantopoulou, Irene, Fountzilas, George

“…In spite the close association of the triple-negative breast cancer immunophenotype with hereditary breast cancers and the BRCA1 pathway, there is a lack of…”
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Correction: Prevalence of BRCA1 Mutations in Familial and Sporadic Greek Ovarian Cancer Cases by Stavropoulou, Alexandra V., Fostira, Florentia, Pertesi, Maroulio, Tsitlaidou, Marianthi, Voutsinas, Gerassimos E., Triantafyllidou, Olga, Bamias, Aristotelis, Dimopoulos, Meletios A., Timotheadou, Eleni, Pectasides, Dimitrios, Christodoulou, Christos, Klouvas, George, Papadimitriou, Christos, Makatsoris, Thomas, Pentheroudakis, George, Aravantinos, Gerasimos, Karydakis, Vassilis, Yannoukakos, Drakoulis, Fountzilas, George, Konstantopoulou, Irene

“…Investing in knowledge society through the European Social Fund. (2013) Correction: Prevalence of BRCA1 Mutations in Familial and Sporadic Greek Ovarian Cancer…”
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In vivo biological activity of the histone deacetylase inhibitor LAQ824 is detectable with 3' -deoxy-3'-[18F]fluorothymidine positron emission tomography by LEYTON, Julius, ALAO, John P, WORKMAN, Paul, VIGUSHIN, David M, ABOAGYE, Eric O, DA COSTA, Marco, STAVROPOULOU, Alexandra V, LATIGO, John R, PERUMAL, Meg, FILIAL, Radhakrishna, QIMIN HE, ATADJA, Peter, LAM, Eric W.-F

“…Histone deacetylase inhibitors (HDACI) are emerging as growth inhibitory compounds that modulate gene expression and inhibit tumor cell proliferation. We…”
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Publisher Correction: An integrated bacterial system for the discovery of chemical rescuers of disease-associated protein misfolding by Matis, Ilias, Delivoria, Dafni Chrysanthi, Mavroidi, Barbara, Papaevgeniou, Nikoletta, Panoutsou, Stefania, Bellou, Stamatia, Papavasileiou, Konstantinos D., Linardaki, Zacharoula I., Stavropoulou, Alexandra V., Vekrellis, Kostas, Boukos, Nikos, Kolisis, Fragiskos N., Gonos, Efstathios S., Margarity, Marigoula, Papadopoulos, Manthos G., Efthimiopoulos, Spiros, Pelecanou, Maria, Chondrogianni, Niki, Skretas, Georgios

“…In the version of this Article originally published, in Fig. 1c–e, on the x axes, the lines labelled ‘Aβ 42 ’ and ‘Aβ 42 (F19S;L34P)’ grouped the data…”
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novel molecule 2-[5-(2-chloroethyl)-2-acetoxy-benzyl]-4-(2-chloroethyl)-phenyl acetate inhibits phosphoinositide 3-kinase/Akt/mammalian target of rapamycin signalling through JNK activation in cancer cells by Ho, Ka-Kei, Rosivatz, Evelyn, Gunn, Richard M, Smith, Mark E.B, Stavropoulou, Alexandra V, Rosivatz, Erika, Numbere, Macba G, Wong, John B, Lafitte, Valerie G.H, Behrendt, Jonathan M, Myatt, Stephen S, Hailes, Helen C, Woscholski, Rüdiger, Lam, Eric W.-F

“…Screening a compound library of compound 48/80 analogues, we identified 2-[5-(2-chloroethyl)-2-acetoxy-benzyl]-4-(2-chloroethyl)-phenyl acetate (E1) as a novel…”
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FOXM1 is a transcriptional target of ERα and has a critical role in breast cancer endocrine sensitivity and resistance by Millour, J, Constantinidou, D, Stavropoulou, A V, Wilson, M S C, Myatt, S S, Kwok, J M-M, Sivanandan, K, Coombes, R C, Medema, R H, Hartman, J, Lykkesfeldt, A E, Lam, E W-F

“…In this study, we investigated the regulation of FOXM1 expression by estrogen receptor α (ERα) and its role in hormonal therapy and endocrine resistance. FOXM1…”
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Prevalence of BRCA1 mutations among 403 women with triple-negative breast cancer: implications for genetic screening selection criteria: a Hellenic Cooperative Oncology Group Study by Fostira, Florentia, Tsitlaidou, Marianthi, Papadimitriou, Christos, Pertesi, Maroulio, Timotheadou, Eleni, Stavropoulou, Alexandra V, Glentis, Stavros, Bournakis, Evangelos, Bobos, Mattheos, Pectasides, Dimitrios, Papakostas, Pavlos, Pentheroudakis, George, Gogas, Helen, Skarlos, Pantelis, Samantas, Epaminontas, Bafaloukos, Dimitrios, Kosmidis, Paris A, Koutras, Angelos, Yannoukakos, Drakoulis, Konstantopoulou, Irene, Fountzilas, George

“…In spite the close association of the triple-negative breast cancer immunophenotype with hereditary breast cancers and the BRCA1 pathway, there is a lack of…”
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A non-synonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriers by Ding, Yuan C., McGuffog, Lesley, Healey, Sue, Friedman, Eitan, Laitman, Yael, Shani-Shimon–Paluch, Kaufman, Bella, Liljegren, Annelie, Lindblom, Annika, Olsson, Håkan, Kristoffersson, Ulf, Stenmark-Askmalm, Marie, Melin, Beatrice, Domchek, Susan M., Nathanson, Katherine L., Rebbeck, Timothy R., Jakubowska, Anna, Lubinski, Jan, Jaworska, Katarzyna, Durda, Katarzyna, Gronwald, Jacek, Huzarski, Tomasz, Cybulski, Cezary, Byrski, Tomasz, Osorio, Ana, Cajal, Teresa Ramóny, Stavropoulou, Alexandra V, Benítez, Javier, Hamann, Ute, Rookus, Matti, Aalfs, Cora M., de Lange, Judith L., Meijers-Heijboer, Hanne E.J., Oosterwijk, Jan C., van Asperen, Christi J., García, Encarna B. Gómez, Hoogerbrugge, Nicoline, Jager, Agnes, van der Luijt, Rob B., Easton, Douglas F., Peock, Susan, Frost, Debra, Ellis, Steve D., Platte, Radka, Fineberg, Elena, Evans, D. Gareth, Lalloo, Fiona, Izatt, Louise, Eeles, Ros, Adlard, Julian, Davidson, Rosemarie, Eccles, Diana, Cole, Trevor, Cook, Jackie, Brewer, Carole, Tischkowitz, Marc, Godwin, Andrew K., Pathak, Harsh, Stoppa-Lyonnet, Dominique, Sinilnikova, Olga M., Mazoyer, Sylvie, Barjhoux, Laure, Léoné, Mélanie, Gauthier-Villars, Marion, Caux-Moncoutier, Virginie, de Pauw, Antoine, Hardouin, Agnès, Berthet, Pascaline, Dreyfus, Hélène, Ferrer, Sandra Fert, Collonge-Rame, Marie-Agnès, Sokolowska, Johanna, Buys, Saundra, Daly, Mary, Miron, Alex, Terry, Mary Beth, Chung, Wendy, John, Esther M, Southey, Melissa, Goldgar, David, Singer, Christian F, Maria, Muy-Kheng Tea, Gschwantler-Kaulich, Daphne, Fink-Retter, Anneliese, Hansen, Thomas v. O., Ejlertsen, Bent, Johannsson, Oskar Th, Offit, Kenneth, Sarrel, Kara, Gaudet, Mia M., Vijai, Joseph, Robson, Mark, Piedmonte, Marion R, Andrews, Lesley, Cohn, David, DeMars, Leslie R.

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Correction: Prevalence of Mutations in Familial and Sporadic Greek Ovarian Cancer Cases by Alexandra V. Stavropoulou, Florentia Fostira, Maroulio Pertesi, Marianthi Tsitlaidou, Gerassimos E. Voutsinas, Olga Triantafyllidou, Aristotelis Bamias, Meletios A. Dimopoulos, Eleni Timotheadou, Dimitrios Pectasides, Christos Christodoulou, George Klouvas, Christos Papadimitriou, Thomas Makatsoris, George Pentheroudakis, Gerasimos Aravantinos, Vassilis Karydakis, Drakoulis Yannoukakos, George Fountzilas, Irene Konstantopoulou

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