Search Results - "STARZL, THOMAS E."

Liver-Specific Deletion of Augmenter of Liver Regeneration Accelerates Development of Steatohepatitis and Hepatocellular Carcinoma in Mice by Gandhi, Chandrashekhar R, Chaillet, J. Richard, Nalesnik, Michael A, Kumar, Sudhir, Dangi, Anil, Demetris, A. Jake, Ferrell, Robert, Wu, Tong, Divanovic, Senad, Stankeiwicz, Traci, Shaffer, Benjamin, Stolz, Donna B, Harvey, Stephen A.K, Wang, Jiang, Starzl, Thomas E

“…Background & Aims Augmenter of liver regeneration (ALR, encoded by GFER ) is a widely distributed pleiotropic protein originally identified as a hepatic growth…”
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Chimerism and Tolerance in Transplantation by Starzl, Thomas E.

“…Studies in experimental models (1953-1956) demonstrated that acquired donor-specific allotolerance in immunologically immature or irradiated animals is…”
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Generation of cloned transgenic pigs rich in omega-3 fatty acids by Lai, L, Kang, J.X, Li, R, Wang, J, Witt, W.T, Yong, H.Y, Hao, Y, Wax, D.M, Murphy, C.N, Rieke, A

“…Meat products are generally low in omega-3 (n-3) fatty acids, which are beneficial to human health. We describe the generation of cloned pigs that express a…”
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Production of α1,3-Galactosyltransferase: Deficient Pigs by Phelps, Carol J., Koike, Chihiro, Vaught, Todd D., Boone, Jeremy, Wells, Kevin D., Chen, Shu-Hung, Ball, Suyapa, Specht, Susan M., Polejaeva, Irina A., Monahan, Jeff A., Jobst, Pete M., Sharma, Sugandha B., Lamborn, Ashley E., Garst, Amy S., Moore, Marilyn, Demetris, Anthony J., Rudert, William A., Bottino, Rita, Bertera, Suzanne, Trucco, Massimo, Starzl, Thomas E., Dai, Yifan, Ayares, David L.

“…The enzyme α1,3-galactosyltransferase (α1,3GT or GGTA1) synthesizes α1,3-galactose (α1,3Gal) epitopes (Galα1,3Galβ1,4GlcNAc-R), which are the major…”
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The course of type 1 hepato-renal syndrome post liver transplantation by Marik, Paul E., Wood, Kelly, Starzl, Thomas E.

“…Background. Hepato-renal syndrome (HRS) is a functional form of renal failure that occurs in patients with end-stage liver disease. Previously considered fatal…”
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History of Clinical Transplantation by Starzl, Thomas E.

“… The emergence of transplantation has seen the development of increasingly potent immunosuppressive agents, progressively better methods of tissue and organ…”
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The long reach of liver transplantation by Starzl, Thomas E

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Functionally important glycosyltransferase gain and loss during catarrhine primate emergence by Koike, Chihiro, Uddin, Monica, Wildman, Derek E, Gray, Edward A, Trucco, Massimo, Starzl, Thomas E, Goodman, Morris

“…A glycosyltransferase, α1,3galactosyltransferase, catalyzes the terminal step in biosynthesis of Galα1,3Galβ1-4GlcNAc-R (αGal), an oligosaccharide cell surface…”
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Antigen Localization and Migration in Immunity and Tolerance by Starzl, Thomas E, Zinkernagel, Rolf M

“…Survival in a hostile environment requires the ability to mount a protective immune response while avoiding a reaction of the immune system against the self…”
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The unfinished legacy of liver transplantation: Emphasis on immunology by Starzl, Thomas E., Lakkis, Fadi G.

“…Liver transplantation radically changed the philosophy of hepatology practice, enriched multiple areas of basic science, and had pervasive ripple effects in…”
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Themes of liver transplantation by Starzl, Thomas E., Fung, John J.

“…Liver transplantation was the product of five interlocking themes. These began in 1958‐1959 with canine studies of then theoretical hepatotrophic molecules in…”
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Immunosuppressive Therapy and Tolerance of Organ Allografts by Starzl, Thomas E

“…In this issue of the Journal, three articles describe several organ-transplant recipients in whom allografts have maintained good function for up to 5 years…”
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Complications of right lobe living donor liver transplantation by Marsh, James W, Gray, Edward, Ness, Roberta, Starzl, Thomas E

“…Background/Aims Right lobar living donor liver transplantation (LDLT) has been controversial because of donor deaths and widely variable reports of recipient…”
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Augmenter of liver regeneration: A fundamental life protein by Nalesnik, Michael A., Gandhi, Chandrashekhar R., Starzl, Thomas E.

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A Journey in Science: The Birth of Organ Transplantation with Particular Reference to Alloengraftment Mechanisms by Starzl, Thomas E.

“…After completing a 1-year surgical internship at Johns Hopkins Hospital in June 1953, I suspended clinical training for 18 months to do an experimental study…”
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Paul Terasaki September 10, 1929-January 26, 2016 by Starzl, Thomas E.

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Upper-extremity transplantation using a cell-based protocol to minimize immunosuppression by Schneeberger, Stefan, Gorantla, Vijay S, Brandacher, Gerald, Zeevi, Adriana, Demetris, Anthony J, Lunz, John G, Metes, Diana M, Donnenberg, Albert D, Shores, Jaimie T, Dimartini, Andrea F, Kiss, Joseph E, Imbriglia, Joseph E, Azari, Kodi, Goitz, Robert J, Manders, Ernest K, Nguyen, Vu T, Cooney, Damon S, Wachtman, Galen S, Keith, Jonathan D, Fletcher, Derek R, Macedo, Camila, Planinsic, Raymond, Losee, Joseph E, Shapiro, Ron, Starzl, Thomas E, Lee, W P Andrew

“…To minimize maintenance immunosuppression in upper-extremity transplantation to favor the risk-benefit balance of this procedure. Despite favorable outcomes,…”
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Human dominant‐negative class II transactivator transgenic pigs – effect on the human anti‐pig T‐cell immune response and immune status by Hara, Hidetaka, Witt, William, Crossley, Tanner, Long, Cassandra, Isse, Kumiko, Fan, Liming, Phelps, Carol J., Ayares, David, Cooper, David K. C., Dai, Yifan, Starzl, Thomas E.

“…Summary Swine leucocyte antigen (SLA) class II molecules on porcine (p) cells play a crucial role in xenotransplantation as activators of recipient human CD4+…”
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The hepatoadrenal syndrome: A common yet unrecognized clinical condition by Marik, Paul E, Gayowski, Timothy, Starzl, Thomas E

“…OBJECTIVE:Adrenal failure is common in critically ill patients, particularly those with sepsis. As liver failure and sepsis are both associated with increased…”
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Cholera toxin-sensitive GTP-binding protein-coupled activation of augmenter of liver regeneration (ALR) receptor and its function in rat kupffer cells by Gandhi, Chandrashekhar R., Murase, Noriko, Starzl, Thomas E.

“…Mitogenic effect of augmenter of liver regeneration (ALR), a protein produced and released by hepatocytes, on hepatocytes in vivo but not in vitro suggests…”
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