Search Results - "STARK, Alejandro"

Early Detection of Lung Cancer Using DNA Promoter Hypermethylation in Plasma and Sputum by Hulbert, Alicia, Jusue-Torres, Ignacio, Stark, Alejandro, Chen, Chen, Rodgers, Kristen, Lee, Beverly, Griffin, Candace, Yang, Andrew, Huang, Peng, Wrangle, John, Belinsky, Steven A, Wang, Tza-Huei, Yang, Stephen C, Baylin, Stephen B, Brock, Malcolm V, Herman, James G

“…CT screening can reduce death from lung cancer. We sought to improve the diagnostic accuracy of lung cancer screening using ultrasensitive methods and a lung…”
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Methylation Biomarker Panel Performance in EsophaCap Cytology Samples for Diagnosing Barrett's Esophagus: A Prospective Validation Study by Wang, Zhixiong, Kambhampati, Swetha, Cheng, Yulan, Ma, Ke, Simsek, Cem, Tieu, Alan H, Abraham, John M, Liu, Xi, Prasath, Vishnu, Duncan, Mark, Stark, Alejandro, Trick, Alexander, Tsai, Hua-Ling, Wang, Hao, He, Yulong, Khashab, Mouen A, Ngamruengphong, Saowanee, Shin, Eun J, Wang, Tza-Huei, Meltzer, Stephen J

“…Barrett's esophagus is the only known precursor of esophageal adenocarcinoma (EAC). Although endoscopy and biopsy are standard methods for Barrett's esophagus…”
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Novel Methylation Biomarker Panel for the Early Detection of Pancreatic Cancer by JOO MI YI, GUZZETTA, Angela A, PAPPOU, Emmanouil P, LACOBUZIO-DONAHUE, Christine A, GOGGINS, Michael G, HERMAN, James G, WANG, Tza-Huei, BAYLIN, Stephen B, AHUJA, Nita, BAILEY, Vasudev J, DOWNING, Stephanie R, VAN NESTE, Leander, CHIAPPINELLI, Katherine B, KEELEY, Brian P, STARK, Alejandro, HERRERA, Alexander, WOLFGANG, Christopher

“…Pancreatic cancer is the fourth leading cause of cancer deaths and there currently is no reliable modality for the early detection of this disease. Here, we…”
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High-throughput sample processing for methylation analysis in an automated, enclosed environment by Stark, Alejandro, Pisanic, Thomas R., Herman, James G., Wang, Tza-Huei

“…Variation in methylcytosine is perhaps the most well-studied epigenetic mechanism of gene regulation. Methods that have been developed and implemented for…”
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Rab8 GTPase regulates Klotho-mediated inhibition of cell growth and progression by directly modulating its surface expression in human non-small cell lung cancer by Chen, Bo, Huang, Shuhong, Pisanic, II, Thomas R., Stark, Alejandro, Tao, Yong, Cheng, Bei, Li, Yue, Wei, Yunyan, Zhao, Weihong, Wang, Tza-Huei, Wu, Jianqing

“…The klotho (KL) gene is an anti-aging gene that has recently been shown to also function as a general tumor suppressor. However, there is currently only…”
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A parallelized microfluidic DNA bisulfite conversion module for streamlined methylation analysis by Stark, Alejandro, Shin, Dong Jin, Pisanic, Thomas, Hsieh, Kuangwen, Wang, Tza-Huei

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Su1216 MOLECULARLY DEFINED CLASSES OF INTERSTITIAL CELLS OF CAJAL (ICC) IN THE MOUSE STOMACH, SMALL INTESTINE, AND LARGE INTESTINE REVEALED BY SINGLE-CELL RNA SEQUENCING by Stark, Alejandro, Zhang, Yuebo, Choi, Egan L., De, Nayan, Hayashi, Yujiro, Bharucha, Adil E., Ordog, Tamas

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Cancer Methylation Biomarker Detection in an Automated, Portable, Multichannel Magnetofluidic Platform by Hasnain, Alexander C., Stark, Alejandro, Trick, Alexander Y., Ma, Ke, Hsieh, Kuangwen, Cheng, Yulan, Meltzer, Stephen J., Wang, Tza-Huei

“…Early detection of cancer is critical to improving clinical outcomes, especially in territories with limited healthcare resources. DNA methylation biomarkers…”
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Droplet Magnetofluidic Assay Platform for Quantitative Methylation-Specific PCR by Stark, Alejandro, Trick, Alexander, Pisanic, 2nd, Thomas R, Wang, Tza-Huei

“…Early cancer detection requires identification of cellular changes resulting from oncogenesis. Abnormal DNA methylation patterns occurring early in tumor…”
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A sample-to-answer droplet magnetofluidic assay platform for quantitative methylation-specific PCR by Stark, Alejandro, Shin, Dong Jin, Wang, Tza-Huei

“…Dysregulation of DNA methylation has been identified as an epigenetic biomarker for numerous cancer types. Gene-specific identification techniques relying on…”
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A parallelized microfluidic DNA bisulfite conversion module for streamlined methylation analysis by Stark, Alejandro, Shin, Dong Jin, Pisanic, Thomas, Hsieh, Kuangwen, Wang, Tza-Huei

“…Aberrant methylation of DNA has been identified as an epigenetic biomarker for numerous cancer types. The vast majority of techniques aimed at detecting…”
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Abstract 3820: Ultrasensitive DNA methylation detection using sputum and plasma for early detection of NSCLC by Chen, Chen, Hulbert, Alicia, Stark, Alejandro, Rodgers, Kristen, Lee, Beverly, Brock, Malcolm, Herman, James

“…Abstract Purpose: The National Lung Cancer Screening Trial provides hope that early detection can result in a reduction of mortality from lung cancer. This…”
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Extraction and processing of circulating DNA from large sample volumes using methylation on beads for the detection of rare epigenetic events by Keeley, Brian, Stark, Alejandro, Pisanic, Thomas R., Kwak, Ruby, Zhang, Yi, Wrangle, John, Baylin, Stephen, Herman, James, Ahuja, Nita, Brock, Malcolm V., Wang, Tza-Huei

“…The use of methylated tumor-specific circulating DNA has shown great promise as a potential cancer biomarker. Nonetheless, the relative scarcity of…”
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Novel score to predict outcome in resected pancreatic neuroendocrine tumors (pNET) by Viudez, Antonio, Laheru, Daniel A., Stark, Alejandro, Azad, Nilofer Saba, Wolfgang, Christopher Lee, Baylin, Stephen, Herman, James Gordon, Maleki, Zahra, De Jesus-Acosta, Ana

“…Abstract only…”
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A new immunohistochemistry prognostic score (IPS) for recurrence and survival in resected pancreatic neuroendocrine tumors (PanNET) by Viúdez, Antonio, Carvalho, Filipe L F, Maleki, Zahra, Zahurak, Marianna, Laheru, Daniel, Stark, Alejandro, Azad, Nilofer S, Wolfgang, Christopher L, Baylin, Stephen, Herman, James G, De Jesus-Acosta, Ana

“…Pancreatic neuroendocrine tumor (PanNET) is a neoplastic entity in which few prognostic factors are well-known. Here, we aimed to evaluate the prognostic…”
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A new immunohistochemistry prognostic score (IPS) for recurrence and survival in pancreatic neuroendocrine tumors (PanNET) by Viudez, Antonio, Carvalho, Filipe LF, Maleki, Zahra, Zahurak, Marianna, Laheru, Daniel A., Stark, Alejandro, Azad, Nilofer Saba, Wolfgang, Christopher Lee, Baylin, Stephen, Herman, James Gordon, De Jesus-Acosta, Ana

“…Abstract only 241 Background: We aimed to evaluate the expression and prognostic significance of N-myc downstream-regulated gen-1 (NDRG-1), O 6 -methylguanine…”
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Correction: A new immunohistochemistry prognostic score (IPS) for recurrence and survival in resected pancreatic neuroendocrine tumors (PanNET) by Viúdez, Antonio, Carvalho, Filipe L F, Maleki, Zahra, Zahurak, Marianna, Laheru, Daniel, Stark, Alejandro, Azad, Nilofer S, Wolfgang, Christopher L, Baylin, Stephen, Herman, James G, De Jesus-Acosta, Ana

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The promise of methylation on beads for cancer detection and treatment by Guzzetta, Angela A, Pisanic Ii, Thomas R, Sharma, Prateek, Yi, Joo Mi, Stark, Alejandro, Wang, Tza-Huei, Ahuja, Nita

“…Despite numerous technical hurdles, the realization of true personalized medicine is becoming a progressive reality for the future of patient care. With the…”
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Blood-based screening for methylation changes in colorectal cancer patients using novel nanotechnologies by Ahuja, Nita, Kwak, Ruby, Keeley, Brian, Stark, Alejandro, Guzzetta, Angela Anna, Wolfgang, Christopher Lee, Herman, James Gordon, Iacobuzio-Donahue, Christine A, Wang, Tza Huei

“…Abstract only 384 Background: Identification of blood-based biomarkers for cancer screening is essential in order to develop novel and minimally invasive…”
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DNA methylation density analysis via fluorescent dye incorporation by Keeley, Brian P., Bailey, Vasudev J., Yin, Chao, Passlack, Katrin, Stark, Alejandro, Carraway, Hetty E., Baylin, Stephen B., Herman, James G., Wang, Tza-Huei “Jeff”

“…Abstract Background: Aberrant DNA methylation of cytosine nucleotides within the promoter region of tumor suppressor genes provides an epigenetic mechanism of…”
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