Search Results - "STANBRIDGE, E. J"

Anti-angiogenic and tumor-suppressive roles of candidate tumor-suppressor gene, Fibulin-2, in nasopharyngeal carcinoma by Law, E W L, Cheung, A K L, Kashuba, V I, Pavlova, T V, Zabarovsky, E R, Lung, H L, Cheng, Y, Chua, D, Lai-wan Kwong, D, Tsao, S W, Sasaki, T, Stanbridge, E J, Lung, M L

“…Fibulin-2 ( FBLN2 ) has been identified as a candidate tumor-suppressor gene in nasopharyngeal carcinoma (NPC). Originally identified through a chromosome 3…”
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Tumor suppressor Alpha B-crystallin (CRYAB) associates with the cadherin/catenin adherens junction and impairs NPC progression-associated properties by Huang, Z, Cheng, Y, Chiu, P M, Cheung, F M F, Nicholls, J M, Kwong, D L-W, Lee, A W M, Zabarovsky, E R, Stanbridge, E J, Lung, H L, Lung, M L

“…Alpha B-crystallin ( CRYAB ) maps within the nasopharyngeal carcinoma (NPC) tumor-suppressive critical region 11q22-23 and its downregulation is significantly…”
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Endocervical glandular neoplasia associated with lobular endocervical glandular hyperplasia is HPV-independent and correlates with carbonic anhydrase-IX expression: a Gynaecological Oncology Group Study by Liao, S Y, Rodgers, W H, Kauderer, J, Darcy, K M, Carter, R, Susumu, N, Nagao, S, Walker, J L, Hatae, M, Stanbridge, E J

“…Background: Lobular endocervical glandular hyperplasia (LEGH) is a rare lesion of the uterine cervix. It has been proposed that LEGH may represent a precursor…”
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Identification of a tumor suppressive critical region mapping to 3p14.2 in esophageal squamous cell carcinoma and studies of a candidate tumor suppressor gene, ADAMTS9 by LO, P. H. Y, LEUNG, A. C. C, SRIVASTAVA, G, TANG, Jc .. O, TSAO, S. W, LUNG, M. L, KWOK, C. Y. C, CHEUNG, W. S. Y, KO, J. M. Y, YANG, L. C, LAW, S, WANG, L. D, LI, J, STANBRIDGE, E. J

“…A gene critical to esophageal cancer has been identified. Functional studies using microcell-mediated chromosome transfer of intact and truncated donor…”
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Expression of cell surface transmembrane carbonic anhydrase genes CA9 and CA12 in the human eye: overexpression of CA12 (CAXII) in glaucoma by Liao, S-Y, Ivanov, S, Ivanova, A, Ghosh, S, Cote, M A, Keefe, K, Coca-Prados, M, Stanbridge, E J, Lerman, M I

“…Purpose: Carbonic anhydrase enzymes (CAs) are universally involved in many fundamental physiological processes, including acid base regulation and fluid…”
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Carbonic anhydrase IX (CA-IX) and high-risk human papillomavirus (H-HPV) as diagnostic biomarkers of cervical dysplasia neoplasia in Japanese women with a cytologic diagnosis of atypical glandular cells (AGC): a Gynecologic Oncology Group (GOG) Study by Liao, S-Y, Rodgers, W H, Kauderer, J, Bonfiglio, T A, Darcy, K M, Carter, R, Levine, L, Spirtos, N M, Susumu, N, Fujiwara, K, Walker, J L, Hatae, M, Stanbridge, E J

“…Background: High-risk human papillomavirus (H-HPV) infection is linked to cervical neoplasia but its role in detecting cervical glandular lesions (GLs) is…”
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Comparison between pimonidazole binding, oxygen electrode measurements, and expression of endogenous hypoxia markers in cancer of the uterine cervix by Jankovic, B., Aquino‐Parsons, C., Raleigh, J. A., Stanbridge, E. J., Durand, R. E., Banath, J. P., MacPhail, S. H., Olive, P. L.

“…Background: Although tumor hypoxia has been associated with a more aggressive phenotype and lower cure rate, there is no consensus as to the method best suited…”
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Direct evidence for the contribution of activated N-ras and K-ras oncogenes to increased intrinsic radiation resistance in human tumor cell lines by BERNHARD, Eric J, STANBRIDGE, Eric J, GUPTA, Swati, GUPTA, Anjali K, SOTO, Daniel, BAKANAUSKAS, Vincent J, CERNIGLIA, George J, MUSCHEL, Ruth J, MCKENNA, W. Gillies

“…Transformation with ras oncogenes results in increased radiation sur vival in many but not all cells. In addition, prenyltransferase inhibitors which inhibit…”
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STRA13 expression and subcellular localisation in normal and tumour tissues: implications for use as a diagnostic and differentiation marker by Ivanova, A, Liao, S-Y, Lerman, M I, Ivanov, S, Stanbridge, E J

“…Background: STRA13 is a bHLH transcription factor that plays a crucial role in cell differentiation, proliferation, apoptosis, and response to hypoxia…”
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Identification of the MN/CA9 protein as a reliable diagnostic biomarker of clear cell carcinoma of the kidney by LIAO, S.-Y, AURELIO, O. N, JAN, K, ZAVADA, J, STANBRIDGE, E. J

“…The MN/CA9 protein is a tumor-associated antigen that has been shown to have diagnostic utility in identifying cervical dysplasia and carcinoma. MN/CA9…”
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Human MN/CA9 gene, a novel member of the carbonic anhydrase family : Structure and exon to protein domain relationships by OPAVSKY, R, PASTOREKOVA, S, ZELNIK, V, GIBADULINOVA, A, STANBRIDGE, E. J, ZAVADA, J, KETTMANN, R, PASTOREK, J

“…We have isolated, sequenced, and characterized a human MN/CA9 gene. This gene is a novel member of the carbonic anhydrase (CA) family, which codes for widely…”
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Identification of the MN antigen as a diagnostic biomarker of cervical intraepithelial squamous and glandular neoplasia and cervical carcinomas by Liao, SY, Brewer, C, Zavada, J, Pastorek, J, Pastorekova, S, Manetta, A, Berman, ML, DiSaia, PJ, Stanbridge, EJ

“…A new tumor-associated antigen, MN, has been identified whose expression correlates with the tumorigenic phenotype of HeLa x fibroblast somatic cell hybrids…”
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Progression of colorectal cancer is associated with multiple tumor suppressor gene defects but inhibition of tumorigenicity is accomplished by correction of any single defect via chromosome transfer by GOYETTE, M. C, CHO, K, FASCHING, C. L, LEVY, D. B, KINZLER, K. W, PARASKEVA, C, VOGESTGEIN, B, STANBRIDGE, E. J

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Human Tumor Suppressor Genes by Stanbridge, E J

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Growth suppression of human breast cancer cells by the introduction of a wild-type p53 gene by Casey, G, Lo-Hsueh, M, Lopez, M E, Vogelstein, B, Stanbridge, E J

“…Mutations in the p53 gene are associated with a wide variety of human tumors, including those of the breast. To assess functionally the role of the p53 gene in…”
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Characterization of the MN/CA 9 promoter proximal region: a role for specificity protein (SP) and activator protein 1 (AP1) factors by Kaluzová, M, Pastoreková, S, Svastová, E, Pastorek, J, Stanbridge, E J, Kaluz, S

“…MN/CA IX (MN) is a tumour-associated isoenzyme of the carbonic anhydrase family. Previous deletion analysis of the MN promoter established that protected…”
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Dissection of Ras-Dependent Signaling Pathways Controlling Aggressive Tumor Growth of Human Fibrosarcoma Cells: Evidence for a Potential Novel Pathway by Gupta, Swati, Plattner, Rina, Der, Channing J., Stanbridge, Eric J.

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Anti-angiogenic pathway associations of the 3p21.3 mapped BLU gene in nasopharyngeal carcinoma by Cheng, Y, Ho, R L K Y, Chan, K C, Kan, R, Tung, E, Lung, H L, Yau, W L, Cheung, A K L, Ko, J M Y, Zhang, Z F, Luo, D Z, Feng, Z B, Chen, S, Guan, X Y, Kwong, D, Stanbridge, E J, Lung, M L

“…Zinc-finger, MYND-type containing 10 ( ZMYND10 ), or more commonly called BLU, expression is frequently downregulated in nasopharyngeal carcinoma (NPC) and…”
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Identifying Tumor Suppressor Genes in Human Colorectal Cancer by Stanbridge, Eric J.

“…Research on tumor suppressor genes in colorectal cancer has shown that such genes have diverse functions but common characteristics…”
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Introduction of human chromosome 11 via microcell transfer controls tumorigenic expression of HeLa cells by Saxon, P.J., Srivatsan, E.S., Stanbridge, E.J.

“…Both tumorigenic segregant HeLa X human fibroblast hybrids and tumorigenic HeLa (D98/AH‐2) cells can be converted to a non‐tumorigenic state following…”
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