Search Results - "STAMMERS, A"

The relationship between zinc intake and growth in children aged 1–8 years: a systematic review and meta-analysis by Stammers, A-L, Lowe, N M, Medina, M W, Patel, S, Dykes, F, Pérez-Rodrigo, C, Serra-Majam, L, Nissensohn, M, Moran, V H

“…Background/objectives: It is estimated that zinc deficiency affects 17% of the world's population, and because of periods of rapid growth children are at an…”
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Zinc intake, status and indices of cognitive function in adults and children: a systematic review and meta-analysis by Warthon-Medina, M, Moran, V H, Stammers, A-L, Dillon, S, Qualter, P, Nissensohn, M, Serra-Majem, L, Lowe, N M

“…In developing countries, deficiencies of micronutrients are thought to have a major impact on child development; however, a consensus on the specific…”
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Expression of inflammatory cytokines following acute spinal cord injury in a rodent model by Stammers, A.T., Liu, J., Kwon, B.K.

“…Many therapies that have been developed for acute spinal cord injury (SCI) either influence or are influenced by posttraumatic inflammation. Many such…”
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Examining the Role of Ampk for Influencing Myocardial Serca2A Expression and Function in Response to High-Fat Feeding Or Exercise Training by Susser, S.E, Morrisette, M.P, Stammers, A, Zherebitskaya, E, Moffatt, T, Premecz, S, Jassal, D.S, Duhamel, T.A

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The relationship between zinc intake and indices of cognitive function: A systematic review and meta-analyses by Warthon-Medina, M., Dillon, S., Moran, V. Hall, Stammers, A. L., Qualter, P., Nissensohn, M., Majem, L. Serra, Lowe, N. M.

“…Data was extracted from 19 studies across all population groups that met the inclusion and exclusion criteria (12 randomised controlled trials (RCTs), and 7…”
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Aprotinin and methylprednisolone equally blunt cardiopulmonary bypass–induced inflammation in humans by Hill, Gary E., Alonso, Anselmo, Spurzem, John R., Stammers, Alfred H., Robbins, Richard A.

“…Cardiopulmonary bypass induces an inflammatory state characterized by tumor necrosis factor-α release. Integrin CD11b is a neutrophil surface adhesive…”
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Enantioselective Synthesis of α-Hydroxy and α-Amino Phosphonates via Catalytic Asymmetric Hydrogenation by Burk, Mark J, Stammers, Timothy A, Straub, Judith A

“…Cationic rhodium catalysts of the C 2 symmetric DuPHOS (1) and BPE (2) ligands have demonstrated the ability to asymmetrically hydrogenate a novel series of…”
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An update on perfusion safety: does the type of perfusion practice affect the rate of incidents related to cardiopulmonary bypass? by Stammers, Alfred H, Mejak, Brian L

“…Cardiopulmonary bypass (CPB) techniques vary among adult and pediatric patients undergoing cardiac surgery. This may result in a differential conduct of CPB…”
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Molecular Dynamics Simulations and Structure-Based Rational Design Lead to Allosteric HCV NS5B Polymerase Thumb Pocket 2 Inhibitor with Picomolar Cellular Replicon Potency by Hucke, Oliver, Coulombe, René, Bonneau, Pierre, Bertrand-Laperle, Mégan, Brochu, Christian, Gillard, James, Joly, Marc-André, Landry, Serge, Lepage, Olivier, Llinàs-Brunet, Montse, Pesant, Marc, Poirier, Martin, Poirier, Maude, McKercher, Ginette, Marquis, Martin, Kukolj, George, Beaulieu, Pierre L., Stammers, Timothy A.

“…The design and preliminary SAR of a new series of 1H-quinazolin-4-one (QAZ) allosteric HCV NS5B thumb pocket 2 (TP-2) inhibitors was recently reported. To…”
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Anthranilic acid-based Thumb Pocket 2 HCV NS5B polymerase inhibitors with sub-micromolar potency in the cell-based replicon assay by Stammers, Timothy A., Coulombe, René, Duplessis, Martin, Fazal, Gulrez, Gagnon, Alexandre, Garneau, Michel, Goulet, Sylvie, Jakalian, Araz, LaPlante, Steven, Rancourt, Jean, Thavonekham, Bounkham, Wernic, Dominik, Kukolj, George, Beaulieu, Pierre L.

“…Optimization efforts on the anthranilic acid-based Thumb Pocket 2 HCV NS5B polymerase inhibitors 1 and 2 resulted in the identification of multiple structural…”
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Structure-based design of novel HCV NS5B thumb pocket 2 allosteric inhibitors with submicromolar gt1 replicon potency: Discovery of a quinazolinone chemotype by Beaulieu, Pierre L., Coulombe, René, Duan, Jianmin, Fazal, Gulrez, Godbout, Cédrickx, Hucke, Oliver, Jakalian, Araz, Joly, Marc-André, Lepage, Olivier, Llinàs-Brunet, Montse, Naud, Julie, Poirier, Martin, Rioux, Nathalie, Thavonekham, Bounkham, Kukolj, George, Stammers, Timothy A.

“…We describe the structure-based design of a novel lead chemotype that binds to thumb pocket 2 of HCV NS5B polymerase and inhibits cell-based gt1 subgenomic…”
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Discovery of a novel series of non-nucleoside thumb pocket 2 HCV NS5B polymerase inhibitors by Stammers, Timothy A., Coulombe, René, Rancourt, Jean, Thavonekham, Bounkham, Fazal, Gulrez, Goulet, Sylvie, Jakalian, Araz, Wernic, Dominic, Tsantrizos, Youla, Poupart, Marc-André, Bös, Michael, McKercher, Ginette, Thauvette, Louise, Kukolj, George, Beaulieu, Pierre L.

“…A novel series of non-nucleoside thumb pocket 2 HCV NS5B polymerase inhibitors were derived from a fragment-based approach using information from X-ray…”
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Aprotinin Enhances the Endogenous Release of Interleukin-10 After Cardiac Operations by Hill, Gary E, Diego, Robert P, Stammers, Alfred H, Huffman, Suzanne M, Pohorecki, Roman

“…Background. Cardiopulmonary bypass (CPB) is characterized by the systemic release of proinflammatory cytokines, such as tumor necrosis factor-α and the…”
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Perfusion education in the United States at the turn of the century by Stammers, A H

“…The challenges facing institutions charged with the delivery of health care have also affected the delivery of education in the health sciences. In the 30…”
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Recovery of left ventricular function after hypothermic global ischemia. Age-related differences in the isolated working rabbit heart by Bove, E L, Stammers, A H

“…The immature myocardium has a greater tolerance for ischemia than does the mature heart. The effect of ischemia when combined with hypothermia on the newborn…”
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Indole 5-carboxamide Thumb Pocket I inhibitors of HCV NS5B polymerase with nanomolar potency in cell-based subgenomic replicons (part 2): Central amino acid linker and right-hand-side SAR studies by Beaulieu, Pierre L., Chabot, Catherine, Duan, Jianmin, Garneau, Michel, Gillard, James, Jolicoeur, Eric, Poirier, Martin, Poupart, Marc-André, Stammers, Timothy A., Kukolj, George, Tsantrizos, Youla S.

“…In this part 2, new indole 5-carboxamide Thumb Pocket 1 inhibitors of HCV NS5B polymerase are described. Structure–activity relationships (SAR) were explored…”
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Point‐of‐care coagulation monitoring: applications of the thromboelastograph by Stammers, A. H., Bruda, N. L., Gonano, §C., Hartmann, §T.

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Clinical comparison of pulsatile and nonpulsatile perfusion during cardiopulmonary bypass by Song, Z, Wang, C, Stammers, A H

“…Controversy exists concerning the utilization of pulsatile flow during cardiopulmonary bypass (CPB) with regard to improved patient outcomes. The purpose of…”
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Allosteric N-acetamide-indole-6-carboxylic acid thumb pocket 1 inhibitors of hepatitis C virus NS5B polymerase — Acylsulfonamides and acylsulfamides as carboxylic acid replacements by Beaulieu, Pierre L, Coulombe, Rene, Gillard, James, Brochu, Christian, Duan, Jianmin, Garneau, Michel, Jolicoeur, Eric, Kuhn, Peter, Poupart, Marc-Andre, Rancourt, Jean, Stammers, Timothy A, Thavonekham, Bounkham, Kukolj, George

“…Acylsulfonamide and acylsulfamide as surrogates for the carboxylic acid function of N-acetamide-indole-6-carboxylic acids were evaluated as allosteric…”
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Hematological abnormalities in neonatal patients treated with extracorporeal membrane oxygenation (ECMO) by Zavadil, D P, Stammers, A H, Willett, L D, Deptula, J J, Christensen, K A, Sydzyik, R T

“…The physical process of extracorporeal membrane oxygenation (ECMO) results in derangement of the hemostatic mechanism, which may lead to increased morbidity,…”
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