Search Results - "STAMFORD, J"

Stability, transdermal penetration, and cutaneous effects of ascorbic acid and its derivatives by Stamford, Nicholas P J

“…Summary Topically applied antioxidants exert their benefits by offering protection from damaging free radicals and over‐the‐counter cosmeceuticals…”
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Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans by Sönnichsen, B, Koski, L. B, Walsh, A, Marschall, P, Neumann, B, Brehm, M, Alleaume, A.-M, Artelt, J, Bettencourt, P, Cassin, E, Hewitson, M, Holz, C, Khan, M, Lazik, S, Martin, C, Nitzsche, B, Ruer, M, Stamford, J, Winzi, M, Heinkel, R, Röder, M, Finell, J, Häntsch, H, Jones, S. J. M, Jones, M, Piano, F, Gunsalus, K. C, Oegema, K, Gönczy, P, Coulson, A, Hyman, A. A, Echeverri, C. J

“…A key challenge of functional genomics today is to generate well-annotated data sets that can be interpreted across different platforms and technologies…”
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Descending control of pain by Stamford, J A

“…Thanks largely to the study of the brainstem nuclei that mediate stimulation analgesia, the involvement of the monoamines in the descending control of pain is…”
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Actions of tramadol, its enantiomers and principal metabolite, O-desmethyltramadol, on serotonin (5-HT) efflux and uptake in the rat dorsal raphe nucleus by Bamigbade, T A, Davidson, C, Langford, R M, Stamford, J A

“…Tramadol is an atypical centrally acting analgesic agent with relatively weak opioid receptor affinity in comparison with its antinociceptive efficacy…”
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DnaB helicase dynamics in bacterial DNA replication resolved by single-molecule studies by Spinks, Richard R, Spenkelink, Lisanne M, Stratmann, Sarah A, Xu, Zhi-Qiang, Stamford, N Patrick J, Brown, Susan E, Dixon, Nicholas E, Jergic, Slobodan, van Oijen, Antoine M

“…Abstract In Escherichia coli, the DnaB helicase forms the basis for the assembly of the DNA replication complex. The stability of DnaB at the replication fork…”
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Evidence that 5‐hydroxytryptamine release in rat dorsal raphé nucleus is controlled by 5‐HT1A, 5‐HT1B and 5‐HT1D autoreceptors by Davidson, Colin, Stamford, Jonathan A.

“…Electrically stimulated 5‐hydroxytryptamine (5‐HT) release was monitored in slices of rat dorsal raphé nucleus (DRN) by fast cylic voltammetry. Pseudo‐single…”
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Stereospecific effects of ketamine on dopamine efflux and uptake in the rat nucleus accumbens by Hancock, P J, Stamford, J A

“…In addition to being a general anaesthetic, ketamine is a recognized drug of abuse. Many, if not all, drugs of abuse have been shown to increase dopamine…”
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Noradrenergic modulation of serotonin release in rat dorsal and median raphé nuclei via α1 and α2A adrenoceptors by HOPWOOD, S. E, STAMFORD, J. A

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Effects of tramadol stereoisomers on norepinephrine efflux and uptake in the rat locus coeruleus measured by real time voltammetry by Halfenny, D. M., Callado, L. F., Hopwood, S. E., Bamigbade, T. A., Langford, R. M., Stamford, J. A.

“…Despite its structural similarity to codeine, tramadol is an unusual analgesic whose antinociceptive efficacy is not solely a result of opioid actions but also…”
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Effects of sevoflurane on dopamine, glutamate and aspartate release in an in vitro model of cerebral ischaemia by Toner, C.C., Connelly, K, Whelpton, R, Bains, S, Michael-Titus, A.T., McLaughlin, D.P., Stamford, J.A.

“…Release of excitatory amino acids and dopamine plays a central role in neuronal damage after cerebral ischaemia. In the present study, we used an in vitro…”
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Probing brain chemistry by Stamford, J A, Justice, Jr, J B

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The effect of paroxetine on 5-HT efflux in rat dorsal raphe nucleus is potentiated by both 5-HT1A and 5-HT1B/D receptor antagonists by DAVIDSON, C, STAMFORD, J. A

“…Serotonin (5-HT) efflux in slices of rat dorsal raphe nucleus (DRN) was evoked by pseudo one pulse electrical stimulation (20 pulses at 100 Hz, 190 ms train…”
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Actions of the hypnotic anaesthetic, dexmedetomidine, on noradrenaline release and cell firing in rat locus coeruleus slices by Jorm, C M, Stamford, J A

“…We have examined the effects of the highly selective alpha 2-adrenoceptor agonist, dexmedetomidine, on noradrenaline release and cell firing in isolated,…”
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Effect of chronic paroxetine treatment on 5-HT1B and 5-HT1D autoreceptors in rat dorsal raphe nucleus by DAVIDSON, C, STAMFORD, J. A

“…This study reports the effect of chronic paroxetine (10 mg/kg p.o., 21 days) on 5-HT1B and 5-HT1D autoreceptors controlling stimulated 5-HT efflux in slices of…”
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Contrasting effects of chronic paroxetine on 5-HT1A control of dorsal raphe cell firing and 5-HT release by Davidson, Colin, Stamford, Jonathan A

“…TO test the role of 5-HT1A receptors in the action of antidepressants, we investigated the effect of chronic paroxetine (10 mg/kg, p.o. for 21 days) on…”
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Effects of dizocilpine (MK 801) on noradrenaline, serotonin and dopamine release and uptake by Callado, Luis F, Hopwood, Sarah E, Hancock, Pamela J, Stamford, Jonathan A

“…In the present study, we examined the actions of the NMDA antagonist dizocilpine (MK801) on electrically evoked release and uptake of noradrenaline (NA) in the…”
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The canary is dead by Jackson, R. G. M., Stamford, J. A., Strunin, L.

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Effects of chronic tramadol on pre- and post-synaptic measures of monoamine function by Hopwood, Sarah E., Owesson, Catarina A., Callado, Luis F., McLaughlin, Daniel P., Stamford, Jonathan A.

“…The atypical analgesic tramadol has strong structural similarities to the antidepressant venlafaxine and is a mixed noradrenaline (NA) and serotonin (5-HT)…”
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Sodium channel blockade unmasks two temporally distinct mechanisms of striatal dopamine release during hypoxia/hypoglycaemia in vitro by Toner, C.C, Stamford, J.A

“…Massive striatal dopamine release during cerebral ischaemia has been implicated in the resulting neuronal damage. Sodium influx is an early event in the…”
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Ascorbic acid is neuroprotective against global ischaemia in striatum but not hippocampus: histological and voltammetric data by Stamford, Jonathan A, Isaac, Dina, Hicks, Caroline A, Ward, Mark A, Osborne, David J, O'Neill, Michael J

“…Following reports that ascorbic acid (AA) blocks NMDA receptors, we examined its possible neuroprotective properties in vivo (gerbil bilateral carotid artery…”
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