Search Results - "STAMBLER, Nancy"

Phase 1 Study of High-Specific-Activity I-131 MIBG for Metastatic and/or Recurrent Pheochromocytoma or Paraganglioma by Noto, Richard B, Pryma, Daniel A, Jensen, Jessica, Lin, Tess, Stambler, Nancy, Strack, Thomas, Wong, Vivien, Goldsmith, Stanley J

“…No therapies are approved for the treatment of metastatic and/or recurrent pheochromocytoma or paraganglioma (PPGL) in the United States. To determine the…”
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Phase 1 study of PSMA ADC, an antibody‐drug conjugate targeting prostate‐specific membrane antigen, in chemotherapy‐refractory prostate cancer by Petrylak, Daniel P., Kantoff, Philip, Vogelzang, Nicholas J., Mega, Anthony, Fleming, Mark T., Stephenson, Joe J., Frank, Richard, Shore, Neal D., Dreicer, Robert, McClay, Edward F., Berry, William R., Agarwal, Manish, DiPippo, Vincent A., Rotshteyn, Yakov, Stambler, Nancy, Olson, William C., Morris, Stephen A., Israel, Robert J.

“…Background Prostate‐specific membrane antigen (PSMA) is a well‐characterized target that is overexpressed selectively on prostate cancer cells. PSMA…”
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Cumulative Laxation Response with Methylnaltrexone: Implications for Hospitalized Patients with Advanced Illness and Opioid-Induced Constipation by Farchadi, David, Slatkin, Neal E., Stambler, Nancy, Israel, Robert J., Matus, Michael

“…•Cumulative RFL responses were significantly greater with MNTX versus PBO.•Efficacy was similar in patients with lower and higher ECOG functional status…”
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Phase 2a Study of the CCR5 Monoclonal Antibody PRO 140 Administered Intravenously to HIV-Infected Adults by JACOBSON, Jeffrey M, LALEZARI, Jacob P, MADDON, Paul J, MORRIS, Stephen A, OLSON, William C, THOMPSON, Melanie A, FICHTENBAUM, Carl J, SAAG, Michael S, ZINGMAN, Barry S, D'AMBROSIO, Paul, STAMBLER, Nancy, ROTSHTEYN, Yakov, MAROZSAN, Andre J

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Attrition of methylnaltrexone treatment-emergent adverse events in patients with chronic noncancer pain and opioid-induced constipation: a post hoc pooled analysis of two clinical trials [version 2; peer review: 2 approved] by Mehta, Neel, Slatkin, Neal E., Israel, Robert J., Stambler, Nancy

“…Background: Opioids prescribed for the management of chronic noncancer pain are associated with nausea, vomiting, and constipation. Methylnaltrexone, a…”
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Attrition of methylnaltrexone treatment-emergent adverse events in patients with chronic noncancer pain and opioid-induced constipation: a post hoc pooled analysis of two clinical trials [version 1; peer review: 2 approved] by Mehta, Neel, Slatkin, Neal E, Israel, Robert J, Stambler, Nancy

“…Background: Opioids prescribed for the management of chronic noncancer pain are associated with nausea, vomiting, and constipation. Methylnaltrexone, a…”
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Subcutaneous Methylnaltrexone for the Treatment of Opioid-Induced Constipation in Patients with Advanced Illness: A Double-Blind, Randomized, Parallel Group, Dose-Ranging Study by Portenoy, Russell K., MD, Thomas, Jay, MD, PhD, Moehl Boatwright, Michele L., MD, Tran, Diep, MS, Galasso, Frank L., MS, Stambler, Nancy, MS, Von Gunten, Charles F., MD, PhD, Israel, Robert J., MD

“…Abstract Methylnaltrexone, a peripherally-acting quaternary opioid antagonist, is an investigational treatment for opioid-induced constipation in patients with…”
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Subcutaneous methylnaltrexone for treatment of acute opioid-induced constipation: Phase 2 study in rehabilitation after orthopedic surgery by Anissian, Lucas, Schwartz, Harry W., Vincent, Kevin, Vincent, Heather K., Carpenito, Jennifer, Stambler, Nancy, Ramakrishna, Tage

“…BACKGROUND: Methylnaltrexone has been shown to be effective for treating opioid‐induced constipation (OIC) in chronic settings, but its effects on acute OIC…”
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Performance of the Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) in multicenter clinical trials by Cedarbaum, Jesse M., Stambler, Nancy

“…The Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) is a 10-item functional inventory which was devised for use in therapeutic trials in ALS…”
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Rescue-free laxation response with methylnaltrexone treatment in cancer patients with opioid-induced constipation: The impact of baseline ECOG status by Boniol, Scott, Slatkin, Neal E., Stambler, Nancy, Israel, Robert J.

“…Abstract only e24083 Background: Opioid-induced constipation (OIC) is a common side effect of opioid treatment for cancer-related pain. Methylnaltrexone (MNTX)…”
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Physiological characterization of Taxol-induced large-fiber sensory neuropathy in the rat by Cliffer, K D, Siuciak, J A, Carson, S R, Radley, H E, Park, J S, Lewis, D R, Zlotchenko, E, Nguyen, T, Garcia, K, Tonra, J R, Stambler, N, Cedarbaum, J M, Bodine, S C, Lindsay, R M, DiStefano, P S

“…The cancer chemotherapeutic agent Taxol (paclitaxel) causes a dose-related peripheral neuropathy in humans. We produced a dose-dependent large-fiber sensory…”
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Sa1726 ATTRITION OF METHYLNALTREXONE TREATMENT-EMERGENT ADVERSE EVENTS IN PATIENTS WITH CHRONIC NONCANCER PAIN AND OPIOID-INDUCED CONSTIPATION by Mehta, Neel, Slatkin, Neal E., Stambler, Nancy, Israel, Robert J.

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Su1647 – The Influence of Age on Central Nervous System Effects of Methylnaltrexone in Patients with Opioid-Induced Constipation: A Pooled Analysis of 4 Clinical Trials by Liao, Solomon, Slatkin, Neal E., Israel, Robert J., Stambler, Nancy

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S165 Impact of Patient Subgroups on the Efficacy and Safety of Methylnaltrexone for Opioid-Induced Constipation in Patients With Advanced Illness by Mehta, Neel, Shah, Eric D., Israel, Robert J., Stambler, Nancy

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All-Cause Mortality Reduction Associated with Methylnaltrexone Use for Opioid-Induced Bowel Disorders: A Pooled Analysis by Webster, Lynn, Brenner, Darren, Israel, Robert, Stambler, Nancy, Slatkin, Neal

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Repeat Dosing with Subcutaneous Methylnaltrexone: A Pooled Analysis in Patients with and without Cancer by Shah, Eric, Yu, Qi, Slatkin, Neal, Stambler, Nancy, Israel, Robert

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The Influence of Age on Central Effects of Methylnaltrexone in Patients with Opioid-Induced Constipation by Liao, Solomon S., Slatkin, Neal E., Stambler, Nancy

“…Background Methylnaltrexone, a peripherally acting µ-opioid receptor antagonist approved for the treatment of opioid-induced constipation (OIC), has restricted…”
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Treatment with Methylnaltrexone in Patients with Opioid-Induced Constipation with or Without Active Cancer (S812) by Chamberlain, Bruce, Rhiner, Michelle, Slatkin, Neal, Stambler, Nancy, Israel, Robert

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Efficacy Variables in Cancer Versus Noncancer Patients Treated with Methylnaltrexone or Placebo: An Analysis of 2 Placebo-Controlled Studies (S811) by Chamberlain, Bruce, Rhiner, Michelle, Slatkin, Neal, Stambler, Nancy, Israel, Robert

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S0493 Subcutaneous Methylnaltrexone in Cancer and Non-Cancer Patients for Rapid Relief of Opioid-Induced Constipation by Shah, Eric D., Chamberlain, Bruce H., Rhiner, Michelle, Slatkin, Neal E., Stambler, Nancy, Israel, Robert J.

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