Search Results - "STACY, R"
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An in vivo model of human small intestine using pluripotent stem cells
Published in Nature medicine (01-11-2014)“…An in vivo model of the human small intestine is established in mice using human pluripotent stem cells. Differentiation of human pluripotent stem cells…”
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How to improve R&D productivity: the pharmaceutical industry's grand challenge
Published in Nature reviews. Drug discovery (01-03-2010)“…Key Points The biopharmaceutical industry is facing unprecedented challenges to its fundamental business model and currently cannot sustain sufficient…”
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Journal Article Book Review -
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Internal Rotation of the Tibial Component is Frequent in Stiff Total Knee Arthroplasty
Published in Clinical orthopaedics and related research (01-08-2011)“…Background Stiffness complicating TKA is a complex and multifactorial problem. We suspected internally rotated components compromised motion because of pain,…”
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Factors Associated With Hepatitis B Exposure Among People Who Report Using Methamphetamine: National Health and Nutrition Examination Survey 2009–2016
Published in The Journal of infectious diseases (02-01-2020)“…Abstract Background With the nation’s focus on the opioid crisis, methamphetamine has made a comeback, potentially increasing risk for hepatitis B. We examined…”
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De novo formation of insulin-producing "neo-β cell islets" from intestinal crypts
Published in Cell reports (Cambridge) (27-03-2014)“…The ability to interconvert terminally differentiated cells could serve as a powerful tool for cell-based treatment of degenerative diseases, including…”
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A Randomized Trial of Binocular Dig Rush Game Treatment for Amblyopia in Children Aged 7 to 12 Years
Published in Ophthalmology (Rochester, Minn.) (01-03-2019)“…To compare visual acuity (VA) improvement in children aged 7 to 12 years with amblyopia treated with a binocular iPad game plus continued spectacle correction…”
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Applications of SPECT and PET Imaging for the Physiological Evaluation of Lower Extremity Peripheral Artery Disease
Published in International journal of molecular sciences (08-07-2024)“…Peripheral artery disease (PAD) is classified as the narrowing or complete occlusion of the lower extremity arteries due to atherosclerosis. The risk of…”
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Metagenomic analysis of human diarrhea: viral detection and discovery
Published in PLoS pathogens (29-02-2008)“…Worldwide, approximately 1.8 million children die from diarrhea annually, and millions more suffer multiple episodes of nonfatal diarrhea. On average, in up to…”
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How school climate relates to chronic absence: A multi–level latent profile analysis
Published in Journal of school psychology (01-04-2017)“…Chronic absence is a significant problem in schools. School climate may play an important role in influencing chronic absence rates among schools, yet little…”
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A randomized placebo‐controlled phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosis
Published in Muscle & nerve (01-03-2022)“…Introduction/Aims Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative illness with great unmet patient need. We aimed to evaluate whether…”
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Addressing distress management challenges: Recommendations from the consensus panel of the American Psychosocial Oncology Society and the Association of Oncology Social Work
Published in CA: a cancer journal for clinicians (01-09-2021)“…Distress management (DM) (screening and response) is an essential component of cancer care across the treatment trajectory. Effective DM has many benefits,…”
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Journal Article Conference Proceeding -
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A Hydrophobic Target: Using the Paramyxovirus Fusion Protein Transmembrane Domain To Modulate Fusion Protein Stability
Published in Journal of virology (01-09-2019)“…Enveloped viruses utilize surface glycoproteins to bind and fuse with a target cell membrane. The zoonotic Hendra virus (HeV), a member of the family ,…”
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Comparison of Smartphone Ownership, Social Media Use, and Willingness to Use Digital Interventions Between Generation Z and Millennials in the Treatment of Substance Use: Cross-Sectional Questionnaire Study
Published in Journal of medical Internet research (17-04-2019)“…Problematic substance use in adolescence and emerging adulthood is a significant public health concern in the United States due to high recurrence of use rates…”
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Acceptability and willingness to pay for contingency management interventions among parents of young adults with problematic opioid use
Published in Drug and alcohol dependence (01-01-2020)“…•Parents of opioid using young adults have positive perceptions of incentives.•Parents of opioid using young adults are willing to pay for CM services.•Parents…”
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Molecular Imaging of Lower Extremity Peripheral Arterial Disease: An Emerging Field in Nuclear Medicine
Published in Frontiers in medicine (12-01-2022)“…Peripheral arterial disease (PAD) is an atherosclerotic disorder of non-coronary arteries that is associated with vascular stenosis and/or occlusion. PAD…”
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Characterization of Highly Ferulate-Tolerant Acinetobacter baylyi ADP1 Isolates by a Rapid Reverse Engineering Method
Published in Applied and environmental microbiology (25-01-2022)“…Adaptive laboratory evolution (ALE) is a powerful approach for improving phenotypes of microbial hosts. Evolved strains typically contain numerous mutations…”
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Meta-evaluation: Validating program evaluation standards through the United Nations Evaluation Quality Assessment (EQAs)
Published in Evaluation journal of Australasia (01-03-2024)“…The 2015 United Nation’s ‘Eval Year’ declaration heightened program evaluation’s significance in achieving the Sustainable Development Goals. However,…”
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Targeting CD73 in the tumor microenvironment with MEDI9447
Published in Oncoimmunology (02-08-2016)“…MEDI9447 is a human monoclonal antibody that is specific for the ectoenzyme CD73 and currently undergoing Phase I clinical trials. Here we show that MEDI9447…”
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Stem cell-derived human intestinal organoids as an infection model for rotaviruses
Published in mBio (2012)“…Directed differentiation of stem cell lines into intestine-like tissue called induced human intestinal organoids (iHIOs) is now possible (J. R. Spence, C. N…”
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