Search Results - "STABILINI, Angela"

Regulatory T-cells from pancreatic lymphnodes of patients with type-1 diabetes express increased levels of microRNA miR-125a-5p that limits CCR2 expression by Sebastiani, Guido, Ventriglia, Giuliana, Stabilini, Angela, Socci, Carlo, Morsiani, Cristina, Laurenzi, Andrea, Nigi, Laura, Formichi, Caterina, Mfarrej, Bechara, Petrelli, Alessandra, Fousteri, Georgia, Brusko, Todd M., Dotta, Francesco, Battaglia, Manuela

“…Autoimmune type 1 diabetes (T1D) is thought to be caused by a defective immune regulation with regulatory T (Treg) cells playing a fundamental role in this…”
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Altered Frequency and Phenotype of HLA-G-Expressing DC-10 in Type 1 Diabetes Patients at Onset and in Subjects at Risk to Develop the Disease by Amodio, Giada, Mandelli, Alessandra, Curto, Rosalia, Rancoita, Paola M V, Stabilini, Angela, Bonfanti, Riccardo, de Pellegrin, Maurizio, Bosi, Emanuele, Di Serio, Clelia, Battaglia, Manuela, Gregori, Silvia

“…Type 1 diabetes (T1D) is a chronic autoimmune disease resulting in progressive destruction of β-cells. Several factors affecting lymphocyte and…”
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Combined unsupervised and semi-automated supervised analysis of flow cytometry data reveals cellular fingerprint associated with newly diagnosed pediatric type 1 diabetes by Bechi Genzano, Camillo, Bezzecchi, Eugenia, Carnovale, Debora, Mandelli, Alessandra, Morotti, Elisa, Castorani, Valeria, Favalli, Valeria, Stabilini, Angela, Insalaco, Vittoria, Ragogna, Francesca, Codazzi, Valentina, Scotti, Giulia Maria, Del Rosso, Stefania, Mazzi, Benedetta Allegra, De Pellegrin, Maurizio, Giustina, Andrea, Piemonti, Lorenzo, Bosi, Emanuele, Battaglia, Manuela, Morelli, Marco J., Bonfanti, Riccardo, Petrelli, Alessandra

“…An unbiased and replicable profiling of type 1 diabetes (T1D)-specific circulating immunome at disease onset has yet to be identified due to experimental and…”
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Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells by TRESOLDI, Eleonora, DELL'ALBANI, Ilaria, STABILINI, Angela, JOFRA, Tatiana, VALLE, Andrea, GAGLIANI, Nicola, BONDANZA, Attilio, GRAZIA RONCAROLO, Maria, BATTAGLIA, Manuela

“…The clinical use of ex vivo-expanded T-regulatory cells for the treatment of T-cell-mediated diseases has gained increasing momentum. However, the recent…”
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Antigen-Specific Dependence of Tr1-Cell Therapy in Preclinical Models of Islet Transplant by GAGLIANI, Nicola, JOFRA, Tatiana, STABILINI, Angela, VALLE, Andrea, ATKINSON, Mark, RONCAROLO, Maria-Grazia, BATTAGLIA, Manuela

“…Antigen-Specific Dependence of Tr1-Cell Therapy in Preclinical Models of Islet Transplant Nicola Gagliani 1 , 2 , 3 , Tatiana Jofra 1 , Angela Stabilini 1 , 2…”
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Induction of Tolerance in Type 1 Diabetes via Both CD4+CD25+ T Regulatory Cells and T Regulatory Type 1 Cells by BATTAGLIA, Manuela, STABILINI, Angela, DRAGHICI, Elena, MIGLIAVACCA, Barbara, GREGORI, Silvia, BONIFACIO, Ezio, RONCAROLO, Maria-Grazia

“…Induction of Tolerance in Type 1 Diabetes via Both CD4 + CD25 + T Regulatory Cells and T Regulatory Type 1 Cells Manuela Battaglia 1 , Angela Stabilini 1 ,…”
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Rapamycin and Interleukin-10 Treatment Induces T Regulatory Type 1 Cells That Mediate Antigen-Specific Transplantation Tolerance by BATTAGLIA, Manuela, STABILINI, Angela, DRAGHICI, Elena, GREGORI, Silvia, MOCCHETTI, Cristina, BONIFACIO, Ezio, RONCAROLO, Maria-Grazia

“…Rapamycin and Interleukin-10 Treatment Induces T Regulatory Type 1 Cells That Mediate Antigen-Specific Transplantation Tolerance Manuela Battaglia 1 , Angela…”
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Impaired exocrine pancreatic function in different stages of type 1 diabetes by Dozio, Nicoletta, Indirli, Rita, Giamporcaro, Gian Maria, Frosio, Laura, Mandelli, Alessandra, Laurenzi, Andrea, Bolla, Andrea Mario, Stabilini, Angela, Valle, Andrea, Locatelli, Massimo, Cavestro, Giulia Martina, Scavini, Marina, Battaglia, Manuela, Bosi, Emanuele

“…IntroductionAim of this study was to investigate the pancreatic exocrine function in patients with type 1 diabetes (T1D) by multiple non-invasive…”
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Rapamycin combined with anti-CD45RB mAb and IL-10 or with G-CSF induces tolerance in a stringent mouse model of islet transplantation by Gagliani, Nicola, Gregori, Silvia, Jofra, Tatiana, Valle, Andrea, Stabilini, Angela, Rothstein, David M, Atkinson, Mark, Roncarolo, Maria Grazia, Battaglia, Manuela

“…A large pool of preexisting alloreactive effector T cells can cause allogeneic graft rejection following transplantation. However, it is possible to induce…”
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Rapamycin Prevents and Breaks the Anti-CD3–Induced Tolerance in NOD Mice by VALLE, Andrea, JOFRA, Tatiana, STABILINI, Angela, ATKINSON, Mark, RONCAROLO, Maria-Grazia, BATTAGLIA, Manuela

“…Rapamycin Prevents and Breaks the Anti-CD3–Induced Tolerance in NOD Mice Andrea Valle 1 , 2 , Tatiana Jofra 1 , 2 , Angela Stabilini 1 , 2 , Mark Atkinson 3 ,…”
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Reply to Comment on "Stability of human rapamycin-expanded CD4+CD25+ T-regulatory cells" Haematologica 2011;96(9):1357-65 by Tresoldi, E., Dell'Albani, I., Stabilini, A., Jofra, T., Valle, A., Gagliani, N., Bondanza, A., Roncarolo, M. G., Battaglia, M.

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Rapamycin Promotes Expansion of Functional CD4+CD25+FOXP3+ Regulatory T Cells of Both Healthy Subjects and Type 1 Diabetic Patients by Battaglia, Manuela, Stabilini, Angela, Migliavacca, Barbara, Horejs-Hoeck, Jutta, Kaupper, Thomas, Roncarolo, Maria-Grazia

“…CD4+CD25+FOXP3+ T regulatory cells (Tregs) are pivotal for the induction and maintenance of peripheral tolerance in both mice and humans. Rapamycin has been…”
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Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells by Battaglia, Manuela, Stabilini, Angela, Roncarolo, Maria-Grazia

“…Rapamycin is an immunosuppressive compound that is currently used to prevent acute graft rejection in humans. In addition, rapamycin has been shown to allow…”
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Expansion of Th17 cells and functional defects in T regulatory cells are key features of the pancreatic lymph nodes in patients with type 1 diabetes by Ferraro, Alessandra, Socci, Carlo, Stabilini, Angela, Valle, Andrea, Monti, Paolo, Piemonti, Lorenzo, Nano, Rita, Olek, Sven, Maffi, Paola, Scavini, Marina, Secchi, Antonio, Staudacher, Carlo, Bonifacio, Ezio, Battaglia, Manuela

“…Autoimmune diseases, including type 1 diabetes, are thought to have a Th17-cell bias and/or a T-regulatory cell (Treg) defect. Understanding whether this is a…”
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Generation of donor-specific Tr1 cells to be used after kidney transplantation and definition of the timing of their in vivo infusion in the presence of immunosuppression by Mfarrej, Bechara, Tresoldi, Eleonora, Stabilini, Angela, Paganelli, Alessia, Caldara, Rossana, Secchi, Antonio, Battaglia, Manuela

“…Operational tolerance is an alternative to lifelong immunosuppression after transplantation. One strategy to achieve tolerance is by T regulatory cells. Safety…”
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Reduction of Circulating Neutrophils Precedes and Accompanies Type 1 Diabetes by VALLE, Andrea, GIAMPORCARO, Gian Maria, BONFANTI, Riccardo, MESCHI, Franco, DE PELLEGRIN, Maurizio, LESMA, Arianna, ROSSINI, Silvano, PIEMONTI, Lorenzo, MARCHETTI, Piero, DOTTA, Francesco, BOSI, Emanuele, BATTAGLIA, Manuela, SCAVINI, Marina, STABILINI, Angela, GROGAN, Pauline, BIANCONI, Eleonora, SEBASTIANI, Guido, MASINI, Matilde, MAUGERI, Norma, PORRETTI, Laura

“…Human type 1 diabetes (T1D) is an autoimmune disease associated with major histocompatibility complex polymorphisms, β-cell autoantibodies, and autoreactive T…”
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Reduced Follicular Regulatory T Cells in Spleen and Pancreatic Lymph Nodes of Patients With Type 1 Diabetes by Vecchione, Andrea, Jofra, Tatiana, Gerosa, Jolanda, Shankwitz, Kimberly, Di Fonte, Roberta, Galvani, Giuseppe, Ippolito, Elio, Cicalese, Maria Pia, Schultz, Andrew R, Seay, Howie R, Favellato, Mariagrazia, Milardi, Giulia, Stabilini, Angela, Ragogna, Francesca, Grogan, Pauline, Bianconi, Eleonora, Laurenzi, Andrea, Caretto, Amelia, Nano, Rita, Melzi, Raffaela, Danzl, Nichole, Bosi, Emanuele, Piemonti, Lorenzo, Aiuti, Alessandro, Brusko, Todd, Petrovas, Constantinos, Battaglia, Manuela, Fousteri, Georgia

“…In the attempt to understand the origin of autoantibody (AAb) production in patients with and at risk for type 1 diabetes (T1D), multiple studies have analyzed…”
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Autoantibody binding in liquid phase to IL-2 in human sera is not type 1 diabetes specific by Marzinotto, Ilaria, Liberati, Daniela, Brigatti, Cristina, Bonfanti, Riccardo, Stabilini, Angela, Monti, Paolo, Bosi, Emanuele, Piemonti, Lorenzo, Lampasona, Vito

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Genetic determinants of type 1 diabetes in individuals with weak evidence of islet autoimmunity at disease onset by Carrera, Paola, Marzinotto, Ilaria, Bonfanti, Riccardo, Massimino, Luca, Calzavara, Silvia, Favellato, Μariagrazia, Jofra, Tatiana, De Giglio, Valeria, Bonura, Clara, Stabilini, Angela, Favalli, Valeria, Bondesan, Simone, Cicalese, Maria Pia, Laurenzi, Andrea, Caretto, Amelia, Frontino, Giulio, Rigamonti, Andrea, Molinari, Chiara, Scavini, Marina, Sandullo, Federica, Zapparoli, Ettore, Caridi, Nicoletta, Bonfiglio, Silvia, Castorani, Valeria, Ungaro, Federica, Petrelli, Alessandra, Barera, Graziano, Aiuti, Alessandro, Bosi, Emanuele, Battaglia, Manuela, Piemonti, Lorenzo, Lampasona, Vito, Fousteri, Georgia

“…Aims/hypothesis Islet autoantibodies (AAbs) are detected in >90% of individuals with clinically suspected type 1 diabetes at disease onset. A single AAb,…”
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Reduced PD-1 expression on circulating follicular and conventional FOXP3+ Treg cells in children with new onset type 1 diabetes and autoantibody-positive at-risk children by Vecchione, Andrea, Di Fonte, Roberta, Gerosa, Jolanda, Jofra, Tatiana, Cicalese, Maria Pia, Napoleone, Vincenzo, Ippolito, Elio, Galvani, Giuseppe, Ragogna, Francesca, Stabilini, Angela, Bianconi, Eleonora, Grogan, Pauline, Bonura, Clara, Bonfanti, Riccardo, Frontino, Giulio, Nano, Rita, Melzi, Raffaela, De Pellegrin, Maurizio, Laurenzi, Andrea, Meschi, Franco, Barera, Graziano, Rigamonti, Andrea, Indirli, Rita, Bosi, Emanuele, Piemonti, Lorenzo, Aiuti, Alessandro, Battaglia, Manuela, Fousteri, Georgia

“…Autoantibodies (AAbs) are a hallmark of Type 1 diabetes (T1D). Alterations in the frequency and phenotype of follicular helper (Tfh) T cells have been…”
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