Search Results - "ST. CLAIR, MARTY"
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Twenty-Five Years of Lamivudine: Current and Future Use for the Treatment of HIV-1 Infection
Published in Journal of acquired immune deficiency syndromes (1999) (01-06-2018)“…ABSTRACTInnovation in medicine is a dynamic, complex, and continuous process that cannot be isolated to a single moment in time. Anniversaries offer…”
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Long-acting intramuscular cabotegravir and rilpivirine in adults with HIV-1 infection (LATTE-2): 96-week results of a randomised, open-label, phase 2b, non-inferiority trial
Published in The Lancet (British edition) (23-09-2017)“…Cabotegravir and rilpivirine are antiretroviral drugs in development as long-acting injectable formulations. The LATTE-2 study evaluated long-acting…”
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3
Long-Acting Cabotegravir and Rilpivirine after Oral Induction for HIV-1 Infection
Published in The New England journal of medicine (19-03-2020)“…Simplified treatment regimens for HIV-1 may have advantages. In this open-label, randomized, controlled trial, patients with HIV-1 infection who had not…”
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Exploring predictors of HIV-1 virologic failure to long-acting cabotegravir and rilpivirine: a multivariable analysis
Published in AIDS (London) (15-07-2021)“…Efficacy and safety of long-acting cabotegravir (CAB) and rilpivirine (RPV) dosed intramuscularly every 4 or 8 weeks has been demonstrated in three Phase 3…”
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Long-Acting Injectable Cabotegravir + Rilpivirine for HIV Maintenance Therapy: Week 48 Pooled Analysis of Phase 3 ATLAS and FLAIR Trials
Published in Journal of acquired immune deficiency syndromes (1999) (01-12-2020)“…Long-acting (LA) injectable regimens are a potential therapeutic option in people living with HIV-1. ATLAS (NCT02951052) and FLAIR (NCT02938520) were 2…”
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Impact of Integrase Sequences from HIV-1 Subtypes A6/A1 on the In Vitro Potency of Cabotegravir or Rilpivirine
Published in Antimicrobial agents and chemotherapy (15-03-2022)“…The FLAIR study demonstrated noninferiority of monthly long-acting cabotegravir + rilpivirine versus daily oral dolutegravir/abacavir/lamivudine for…”
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Efficacy, Safety, and Durability of Long-Acting Cabotegravir and Rilpivirine in Adults With Human Immunodeficiency Virus Type 1 Infection: 5-Year Results From the LATTE-2 Study
Published in Open forum infectious diseases (01-09-2021)“…Abstract Background In the Long-Acting Antiretroviral Treatment Enabling Trial 2 (LATTE-2) phase 2b study, long-acting (LA) injectable cabotegravir +…”
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Effects of cattle manure and soil parent material on shallow groundwater quality
Published in Agrosystems, geosciences & environment (01-09-2023)“…Livestock are a critical agricultural commodity in the Midwestern United States and are directly linked to row crop production. Chemical and manure nutrient…”
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Long-Term Efficacy, Safety, and Durability of Cabotegravir and Rilpivirine as 2-Drug Oral Maintenance Therapy After 6 Years of Study
Published in Open forum infectious diseases (01-04-2022)“…Abstract Background In the LATTE study, daily oral cabotegravir + rilpivirine demonstrated higher rates of efficacy than efavirenz + 2 nucleoside…”
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Cabotegravir plus rilpivirine, once a day, after induction with cabotegravir plus nucleoside reverse transcriptase inhibitors in antiretroviral-naive adults with HIV-1 infection (LATTE): a randomised, phase 2b, dose-ranging trial
Published in The Lancet infectious diseases (01-10-2015)“…Summary Background In phase 1 trials, the HIV-1 integrase strand transfer inhibitor cabotegravir (GSK1265744) was well tolerated, both alone, and in…”
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Aquifer lithology affects shallow groundwater quality more than nitrogen fertilizer form and placement method in an Iowa agricultural field
Published in Agrosystems, geosciences & environment (2021)“…Excessive nutrient loss threatens local and regional water resources, and many midwestern U.S. states are adopting nutrient reduction strategies to reduce…”
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Safety and Efficacy of GSK2248761, a Next-Generation Nonnucleoside Reverse Transcriptase Inhibitor, in Treatment-Naive HIV-1-Infected Subjects
Published in Antimicrobial Agents and Chemotherapy (01-05-2012)“…GSK2248761 is a novel, once-daily (QD), next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI) with activity against efavirenz-resistant…”
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Limited immune restoration after 3 years' suppression of HIV-1 replication in patients with moderately advanced disease
Published in AIDS (London) (27-09-2002)“…To describe the magnitude of immune restoration after long-term control of HIV-1 replication. DESIGN Prospective study of immune restoration in patients…”
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Antiviral Activity of GW678248, a Novel Benzophenone Nonnucleoside Reverse Transcriptase Inhibitor
Published in Antimicrobial Agents and Chemotherapy (01-10-2005)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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In Vitro Antiviral Activity of the Novel, Tyrosyl-Based Human Immunodeficiency Virus (HIV) Type 1 Protease Inhibitor Brecanavir (GW640385) in Combination with Other Antiretrovirals and against a Panel of Protease Inhibitor-Resistant HIV
Published in Antimicrobial Agents and Chemotherapy (01-09-2007)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Characterization of Human Immunodeficiency Virus (HIV) Infection in Cisgender Men and Transgender Women Who Have Sex With Men Receiving Injectable Cabotegravir for HIV Prevention: HPTN 083
Published in The Journal of infectious diseases (16-11-2021)“…Abstract Background The HIV Prevention Trials Network (HPTN) 083 trial demonstrated that long-acting cabotegravir (CAB-LA) was more effective than tenofovir…”
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Dolutegravir in antiretroviral-naive adults with HIV-1: 96-week results from a randomized dose-ranging study
Published in AIDS (London) (17-07-2013)“…OBJECTIVE:To evaluate the efficacy and safety/tolerability of dolutegravir (DTG, S/GSK1349572), a potent inhibitor of HIV integrase, through the full 96 weeks…”
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Dissolved phosphate concentrations in Iowa shallow groundwater
Published in Journal of environmental quality (01-07-2020)“…Regional groundwater phosphorus (P) concentrations are rarely reported, and it is important to develop a better understanding of background concentrations in…”
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Characterization of Human Immunodeficiency Virus (HIV) Infections in Women Who Received Injectable Cabotegravir or Tenofovir Disoproxil Fumarate/Emtricitabine for HIV Prevention: HPTN 084
Published in The Journal of infectious diseases (16-05-2022)“…Abstract Background HIV Prevention Trials Network 084 demonstrated that long-acting injectable cabotegravir (CAB) was superior to daily oral tenofovir (TFV)…”
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Anti-Human Immunodeficiency Virus Type 1 Activity of the Nonnucleoside Reverse Transcriptase Inhibitor GW678248 in Combination with Other Antiretrovirals against Clinical Isolate Viruses and In Vitro Selection for Resistance
Published in Antimicrobial Agents and Chemotherapy (01-11-2005)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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