Search Results - "STÖHR, Robert"

MicroRNA profiles of prostate carcinoma detected by multiplatform microRNA screening by Wach, Sven, Nolte, Elke, Szczyrba, Jaroslaw, Stöhr, Robert, Hartmann, Arndt, Ørntoft, Torben, Dyrskjøt, Lars, Eltze, Elke, Wieland, Wolf, Keck, Bastian, Ekici, Arif B., Grässer, Friedrich, Wullich, Bernd

“…MicroRNAs (miRNAs) are small RNA molecules that regulate gene expression via posttranscriptional inhibition of protein synthesis. They play a vital role in…”
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Rivaroxaban versus vitamin K antagonist treatment on the progression of coronary calcification: the IRIVASC-trial by Stöhr, Robert, Reinartz, Sebastian, Dirrichs, Timm, Witte, Klaus, Schuh, Alexander, Brandenburg, Vincent

“…Vitamin K antagonists (VKA) remain the only option of anticoagulation for people with mechanical valve replacement and due to their wider availability and…”
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Glucagon-Like Peptide 1 and Its Cleavage Products Are Renoprotective in Murine Diabetic Nephropathy by Moellmann, Julia, Klinkhammer, Barbara Mara, Onstein, Julia, Stöhr, Robert, Jankowski, Vera, Jankowski, Joachim, Lebherz, Corinna, Tacke, Frank, Marx, Nikolaus, Boor, Peter, Lehrke, Michael

“…Incretin-based therapies, including glucagon-like peptide 1 (GLP-1) receptor agonists and dipeptidyl peptidase 4 (DPP-4) inhibitors, are potent…”
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FGF23 in Cardiovascular Disease: Innocent Bystander or Active Mediator? by Stöhr, Robert, Schuh, Alexander, Heine, Gunnar H, Brandenburg, Vincent

“…Fibroblast growth factor-23 (FGF23) is a mainly osteocytic hormone which increases renal phosphate excretion and reduces calcitriol synthesis. These renal…”
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Silencing of the SEC62 gene inhibits migratory and invasive potential of various tumor cells by Greiner, Markus, Kreutzer, Birgit, Jung, Volker, Grobholz, Rainer, Hasenfus, Andrea, Stöhr, Robert Franz, Tornillo, Luigi, Dudek, Johanna, Stöckle, Michael, Unteregger, Gerhard, Kamradt, Jörn, Wullich, Bernd, Zimmermann, Richard

“…Sec62 is part of the protein translocation apparatus in the membrane of the endoplasmic reticulum (ER). In yeast, Sec62 participates in the post‐translational…”
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Annexin A5 reduces early plaque formation in ApoE -/- mice by Stöhr, Robert, Schurgers, Leon, van Gorp, Rick, Jaminon, Armand, Marx, Nikolaus, Reutelingsperger, Chris

“…Annexin A5 (AnxA5) exerts anti-inflammatory, anticoagulant and anti-apoptotic effects through its binding to cell surface expressed phosphatidylserine. We…”
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Prognostic and Predictive Potential of CCL5 Expression in Muscle-Invasive Bladder Cancer Patients by Smolka, Cedric, Eckstein, Markus, Jung, Rudolf, Lieb, Verena, Sikic, Danijel, Stöhr, Robert, Bahlinger, Veronika, Bertz, Simone, Kehlen, Astrid, Hartmann, Arndt, Wullich, Bernd, Taubert, Helge, Wach, Sven

“…Bladder cancer (BC) is the 12th most commonly diagnosed cancer worldwide. Although there are several well-established molecular and immunological…”
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The microRNA profile of prostate carcinoma obtained by deep sequencing by Szczyrba, Jaroslaw, Löprich, Elke, Wach, Sven, Jung, Volker, Unteregger, Gerhard, Barth, Stephanie, Grobholz, Rainer, Wieland, Wolf, Stöhr, Robert, Hartmann, Arndt, Wullich, Bernd, Grässer, Friedrich

“…Prostate cancer is a leading cause of tumor mortality. To characterize the underlying molecular mechanisms, we have compared the microRNA (miRNA) profile of…”
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Intravenous iron supplementation in heart failure patients induces temporary endothelial dysfunction with release of endothelial microvesicles by Mause, Sebastian F, Berger, Martin, Lim, Hwee Ying, Vogt, Felix, Brandenburg, Vincent, Stöhr, Robert

“…Intravenous iron supplementation is an established therapy for patients with heart failure (HF) and concomitant iron deficiency reducing the risk of HF…”
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Technical validation of an RT-qPCR in vitro diagnostic test system for the determination of breast cancer molecular subtypes by quantification of ERBB2, ESR1, PGR and MKI67 mRNA levels from formalin-fixed paraffin-embedded breast tumor specimens by Laible, Mark, Schlombs, Kornelia, Kaiser, Katharina, Veltrup, Elke, Herlein, Stefanie, Lakis, Sotiris, Stöhr, Robert, Eidt, Sebastian, Hartmann, Arndt, Wirtz, Ralph M, Sahin, Ugur

“…MammaTyper is a novel CE-marked in vitro diagnostic RT-qPCR assay which assigns routinely processed breast cancer specimens into the molecular subtypes Luminal…”
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Proficiency testing of PIK3CA mutations in HR+/HER2-breast cancer on liquid biopsy and tissue by Vollbrecht, Claudia, Hoffmann, Inga, Lehmann, Annika, Merkelbach-Bruse, Sabine, Fassunke, Jana, Wagener-Ryczek, Svenja, Ball, Markus, Dimitrova, Lora, Hartmann, Arndt, Stöhr, Robert, Erber, Ramona, Weichert, Wilko, Pfarr, Nicole, Bohlmann, Lisa, Jung, Andreas, Dietmaier, Wolfgang, Dietel, Manfred, Horst, David, Hummel, Michael

“…Precision oncology based on specific molecular alterations requires precise and reliable detection of therapeutic targets in order to initiate the optimal…”
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The combined serum levels of miR‐375 and urokinase plasminogen activator receptor are suggested as diagnostic and prognostic biomarkers in prostate cancer by Wach, Sven, Al‐Janabi, Omar, Weigelt, Katrin, Fischer, Kersten, Greither, Thomas, Marcou, Marios, Theil, Gerit, Nolte, Elke, Holzhausen, Hans‐Juergen, Stöhr, Robert, Huppert, Verena, Hartmann, Arndt, Fornara, Paolo, Wullich, Bernd, Taubert, Helge

“…This study aimed to assess the applicability of miR‐375 in combination with the soluble urokinase plasminogen activator receptor (suPAR) protein as a…”
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Early risk markers for severe clinical course and fatal outcome in German patients with COVID-19 by Balfanz, Paul, Hartmann, Bojan, Müller-Wieland, Dirk, Kleines, Michael, Häckl, Dennis, Kossack, Nils, Kersten, Alexander, Cornelissen, Christian, Müller, Tobias, Daher, Ayham, Stöhr, Robert, Bickenbach, Johannes, Marx, Gernot, Marx, Nikolaus, Dreher, Michael

“…Some patients with Corona Virus Disease 2019 (COVID-19) develop a severe clinical course with acute respiratory distress syndrome (ARDS) and fatal outcome…”
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Multinational proficiency tests for EGFR exon 20 insertions reveal that the assay design matters by Ihle, Michaela A., Heydt, Carina, Schultheis, Anne Maria, Stöhr, Robert, Haller, Florian, Herold, Sylvia, Aust, Daniela, Dietmaier, Wolfgang, Evert, Matthias, Eszlinger, Markus, Haak, Anja, Laßmann, Silke, Vorholt, Daniela, Breitenbücher, Frank, Werner, Martin, Streubel, Anna, Mairinger, Thomas, Grassow-Narlik, Maja, Merkelbach-Bruse, Sabine

“…Insertion mutations in exon 20 of the epidermal growth factor receptor gene ( EGFR exon20ins) are rare, heterogeneous alterations observed in non-small cell…”
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Unobtrusive Nocturnal Heartbeat Monitoring by a Ballistocardiographic Sensor in Patients with Sleep Disordered Breathing by Zink, Matthias Daniel, Brüser, Christoph, Stüben, Björn-Ole, Napp, Andreas, Stöhr, Robert, Leonhardt, Steffen, Marx, Nikolaus, Mischke, Karl, Schulz, Jörg B., Schiefer, Johannes

“…Sleep disordered breathing (SDB) is known for fluctuating heart rates and an increased risk of developing arrhythmias. The current reference for heartbeat…”
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MET Amplification in Non-Small Cell Lung Cancer (NSCLC)—A Consecutive Evaluation Using Next-Generation Sequencing (NGS) in a Real-World Setting by Schubart, Christoph, Stöhr, Robert, Tögel, Lars, Fuchs, Florian, Sirbu, Horia, Seitz, Gerhard, Seggewiss-Bernhardt, Ruth, Leistner, Rumo, Sterlacci, William, Vieth, Michael, Seidl, Christoph, Mugler, Michael, Kapp, Markus, Hohenforst-Schmidt, Wolfgang, Hartmann, Arndt, Haller, Florian, Erber, Ramona

“…In non-small cell lung cancer (NSCLC), approximately 1–3% of cases harbor an increased gene copy number (GCN) of the MET gene. This alteration can be due to de…”
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Piwi-like 1 and -2 protein expression levels are prognostic factors for muscle invasive urothelial bladder cancer patients by Eckstein, Markus, Jung, Rudolf, Weigelt, Katrin, Sikic, Danijel, Stöhr, Robert, Geppert, Carol, Agaimy, Abbas, Lieb, Verena, Hartmann, Arndt, Wullich, Bernd, Wach, Sven, Taubert, Helge

“…Piwi-like proteins are essential for stem-cell maintenance and self-renewal in multicellular organisms. We analyzed the expression of Piwi-like 1 and Piwi-like…”
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Identification of ZNF217, hnRNP‐K, VEGF‐A and IPO7 as targets for microRNAs that are downregulated in prostate carcinoma by Szczyrba, Jaroslaw, Nolte, Elke, Hart, Martin, Döll, Celina, Wach, Sven, Taubert, Helge, Keck, Bastian, Kremmer, Elisabeth, Stöhr, Robert, Hartmann, Arndt, Wieland, Wolf, Wullich, Bernd, Grässer, Friedrich A.

“…In primary prostate cancer (PCa), a major cause of cancer‐related death in men, the expression of various microRNAs (miRNAs) is deregulated. We previously…”
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Analysis of CXCL9, PD1 and PD-L1 mRNA in Stage T1 Non-Muscle Invasive Bladder Cancer and Their Association with Prognosis by Kubon, Jennifer, Sikic, Danijel, Eckstein, Markus, Weyerer, Veronika, Stöhr, Robert, Neumann, Angela, Keck, Bastian, Wullich, Bernd, Hartmann, Arndt, Wirtz, Ralph M, Taubert, Helge, Wach, Sven

“…Non-muscle invasive bladder cancer (NMIBC), which is characterized by a recurrence rate of approximately 30% and very long treatment times, remains a major…”
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MDR1 and ERCC1 Expression Predict Outcome of Patients with Locally Advanced Bladder Cancer Receiving Adjuvant Chemotherapy by Hoffmann, Andreas-Claudius, Wild, Peter, Leicht, Christina, Bertz, Simone, Danenberg, Kathleen D., Danenberg, Peter V., Stöhr, Robert, Stöckle, Michael, Lehmann, Jan, Schuler, Martin, Hartmann, Arndt

“…PURPOSE: The role of adjuvant chemotherapy in patients with locally advanced bladder cancer still remains to be defined. We hypothesized that assessing the…”
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