Search Results - "SRIVATSAN, Eri S"

Cellular senescence and tumor suppressor gene p16 by Rayess, Hani, Wang, Marilene B., Srivatsan, Eri S.

“…Cellular senescence is an irreversible arrest of cell growth. Biochemical and morphological changes occur during cellular senescence, including the formation…”
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Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma by Wilken, Reason, Veena, Mysore S, Wang, Marilene B, Srivatsan, Eri S

“…Curcumin (diferuloylmethane) is a polyphenol derived from the Curcuma longa plant, commonly known as turmeric. Curcumin has been used extensively in Ayurvedic…”
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Cell-Free RNA as a Novel Biomarker for Response to Therapy in Head & Neck Cancer by Tosevska, Anela, Morselli, Marco, Basak, Saroj K, Avila, Luis, Mehta, Parag, Wang, Marilene B, Srivatsan, Eri S, Pellegrini, Matteo

“…Liquid biopsies are gaining more traction as non-invasive tools for the diagnosis and monitoring of cancer. In a new paradigm of cancer treatment, a…”
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Hyperactivated JNK Is a Therapeutic Target in pVHL-Deficient Renal Cell Carcinoma by JIABIN AN, HUIREN LIU, MAGYAR, Clara E, YANCHUAN GUO, VEENA, Mysore S, SRIVATSAN, Eri S, JIAOTI HUANG, RETTIG, Matthew B

“…Clear cell renal cell carcinomas (RCC), the major histologic subtype of RCC accounting for more than 80% of cases, are typified by biallelic inactivation of…”
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Enhanced CTLA‐4 blockade anti‐tumor immunity with APG‐157 combination in a murine head and neck cancer by Shin, Daniel Sanghoon, Basak, Saroj, Veena, Mysore S., Comin‐Anduix, Begoña, Bhattacharya, Arjun, Dong, Tien S., Ko, Albert, Han, Philip, Jacobs, Jonathan, Moatamed, Neda A., Avila, Luis, Pellegrini, Matteo, Wang, Marilene, Srivatsan, Eri S.

“…Background A phase I clinical study for patients with locally advanced H&N cancer with a new class of botanical drug APG‐157 provided hints of potential…”
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Curcumin Suppresses Growth of Head and Neck Squamous Cell Carcinoma by LOTEMPIO, Maria M, VEENA, Mysore S, STEELE, Helen L, RAMAMURTHY, Bharathi, RAMALINGAM, Tirunelveli S, COHEN, Alen N, CHAKRABARTI, Rita, SRIVATSAN, Eri S, WANG, Marilene B

“…Purpose: The purpose of this study was to determine whether curcumin would trigger cell death in the head and neck squamous cell carcinoma (HNSCC) cell lines…”
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The CD44(high) tumorigenic subsets in lung cancer biospecimens are enriched for low miR-34a expression by Basak, Saroj K, Veena, Mysore S, Oh, Scott, Lai, Chi, Vangala, Sitaram, Elashoff, David, Fishbein, Michael C, Sharma, Sanjai, Rao, Nagesh P, Rao, Dinesh, Phan, Ryan, Srivatsan, Eri S, Batra, Raj K

“…Cellular heterogeneity is an integral part of cancer development and progression. Progression can be associated with emergence of cells that exhibit high…”
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Human papillomavirus in oropharyngeal cancer: The changing face of a disease by Mallen-St Clair, Jon, Alani, Mustafa, Wang, Marilene B., Srivatsan, Eri S.

“…The last decade has brought about an unexpected rise in oropharyngeal squamous cell carcinoma (OPSCC) primarily in white males from the ages of 40–55years,…”
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EGFR pathway targeting drugs in head and neck cancer in the era of immunotherapy by Kang, James J., Ko, Albert, Kil, Sang Hoon, Mallen-St. Clair, Jon, Shin, Daniel Sanghoon, Wang, Marilene B., Srivatsan, Eri S.

“…Receptor tyrosine kinases (RTKs) are cell surface receptors that bind growth factor ligands and initiate cellular signaling. Of the 20 classes of RTKs, 7…”
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A randomized, phase 1, placebo‐controlled trial of APG‐157 in oral cancer demonstrates systemic absorption and an inhibitory effect on cytokines and tumor‐associated microbes by Basak, Saroj K., Bera, Alakesh, Yoon, Alexander J., Morselli, Marco, Jeong, Chan, Tosevska, Anela, Dong, Tien S., Eklund, Michael, Russ, Eric, Nasser, Hassan, Lagishetty, Venu, Guo, Rong, Sajed, Dipti, Mudgal, Sharmila, Mehta, Parag, Avila, Luis, Srivastava, Meera, Faull, Kym, Jacobs, Jonathan, Pellegrini, Matteo, Shin, Daniel Sanghoon, Srivatsan, Eri S., Wang, Marilene B.

“…Background Although curcumin's effect on head and neck cancer has been studied in vitro and in vivo, to the authors' knowledge its efficacy is limited by poor…”
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Dysregulation of hsa-miR-34a and hsa-miR-449a leads to overexpression of PACS-1 and loss of DNA damage response (DDR) in cervical cancer by Veena, Mysore S., Raychaudhuri, Santanu, Basak, Saroj K., Venkatesan, Natarajan, Kumar, Parameet, Biswas, Roopa, Chakrabarti, Rita, Lu, Jing, Su, Trent, Gallagher-Jones, Marcus, Morselli, Marco, Fu, Haiqing, Pellegrini, Matteo, Goldstein, Theodore, Aladjem, Mirit I., Rettig, Matthew B., Wilczynski, Sharon P., Shin, Daniel Sanghoon, Srivatsan, Eri S.

“…We have observed overexpression of PACS-1, a cytosolic sorting protein in primary cervical tumors. Absence of exonic mutations and overexpression at the RNA…”
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Liposome-Encapsulated Curcumin Suppresses Growth of Head and Neck Squamous Cell Carcinoma In vitro and in Xenografts through the Inhibition of Nuclear Factor κB by an AKT-Independent Pathway by Wang, Dorothy, Veena, Mysore S., Stevenson, Kerry, Tang, Christopher, Ho, Baran, Suh, Jeffrey D., Duarte, Victor M., Faull, Kym F., Mehta, Kapil, Srivatsan, Eri S., Wang, Marilene B.

“…Purpose: The purpose of this study was to determine whether a liposomal formulation of curcumin would suppress the growth of head and neck squamous cell…”
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Curcumin Treatment Suppresses IKKβ Kinase Activity of Salivary Cells of Patients with Head and Neck Cancer: A Pilot Study by KIM, Suejung G, VEENA, Mysore S, SRIVATSAN, Eri S, WANG, Marilene B, BASAK, Saroj K, HAN, Eugene, TAJIMA, Tracey, GJERTSON, David W, STARR, Joshua, EIDELMAN, Ofer, POLLARD, Harvey B, SRIVASTAVA, Meera

“…To determine whether curcumin would inhibit IκB kinase β (IKKβ) kinase activity and suppress expression of proinflammatory cytokines in head and neck squamous…”
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A review of gigaxonin mutations in giant axonal neuropathy (GAN) and cancer by Kang, James J., Liu, Isabelle Y., Wang, Marilene B., Srivatsan, Eri S.

“…Gigaxonin, the product of GAN gene localized to chromosome 16, is associated with the early onset neuronal degeneration disease giant axonal neuropathy ( GAN…”
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Synergistic Activity with NOTCH Inhibition and Androgen Ablation in ERG-Positive Prostate Cancer Cells by Mohamed, Ahmed A, Tan, Shyh-Han, Xavier, Charles P, Katta, Shilpa, Huang, Wei, Ravindranath, Lakshmi, Jamal, Muhammad, Li, Hua, Srivastava, Meera, Srivatsan, Eri S, Sreenath, Taduru L, McLeod, David G, Srinivasan, Alagarsamy, Petrovics, Gyorgy, Dobi, Albert, Srivastava, Shiv

“…The oncogenic activation of the ETS-related gene ( ) due to gene fusions is present in over half of prostate cancers in Western countries. Because of its high…”
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A sensitive LC-MS assay using derivatization with boron trifluoride to quantify curcuminoids in biological samples by Yoon, Alexander J., Wu, Haiqiang, Pan, Roy D., Teter, Bruce, Cipolla, Jack, Chang, Edwin, Avila, Luis Z., Basak, Saroj K., Srivatsan, Eri S., Wang, Marilene B., Cole, Greg M., Frautschy, Sally A., Hampton, Phillip D., Faull, Kym F.

“…A procedure is described to measure curcumin (C), demethoxycurcumin (DMC), bisdemethoxycurcumin (BDMC), tetrahydrocurcumim (TC) and their glucuronidated…”
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Curcumin enhances the effect of cisplatin in suppression of head and neck squamous cell carcinoma via inhibition of IKKβ protein of the NFκB pathway by Duarte, Victor M, Han, Eugene, Veena, Mysore S, Salvado, Amanda, Suh, Jeffrey D, Liang, Li-Jung, Faull, Kym F, Srivatsan, Eri S, Wang, Marilene B

“…Previous experiments have shown that curcumin or cisplatin treatment suppresses growth of head and neck squamous cell carcinoma (HNSCC). To study the potential…”
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Liposome encapsulated curcumin-difluorinated (CDF) inhibits the growth of cisplatin resistant head and neck cancer stem cells by Basak, Saroj K, Zinabadi, Alborz, Wu, Arthur W, Venkatesan, Natarajan, Duarte, Victor M, Kang, James J, Dalgard, Clifton L, Srivastava, Meera, Sarkar, Fazlul H, Wang, Marilene B, Srivatsan, Eri S

“…Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer, with 600,000 new cases every year worldwide. Although chemotherapeutics exist,…”
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Alternative mRNA splicing in colon cancer causes loss of expression of neural cell adhesion molecule by Huerta, Sergio, Srivatsan, Eri S., Venkatesan, Natarajan, Peters, Julius, Moatamed, Farhad, Renner, Steve, Livingston, Edward H.

“…Background. The neural cell adhesion molecule (NCAM) has numerous isoforms resulting from alternative splicing of mRNA. The 3 major isoforms found in adult…”
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Cystatin E/M Suppresses Tumor Cell Growth through Cytoplasmic Retention of NF-κB by Soh, Hendrick, Venkatesan, Natarajan, Veena, Mysore S., Ravichandran, Sandhiya, Zinabadi, Alborz, Basak, Saroj K., Parvatiyar, Kislay, Srivastava, Meera, Liang, Li-Jung, Gjertson, David W., Torres, Jorge Z., Moatamed, Neda A., Srivatsan, Eri S.

“…We and others have shown that the cystatin E/M gene is inactivated in primary human tumors, pointing to its role as a tumor suppressor gene. However, the…”
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