Search Results - "SPRUNGER, D. B"
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Pulmonary fibrosis is associated with an elevated risk of thromboembolic disease
Published in The European respiratory journal (01-01-2012)“…Recent epidemiological studies have suggested an increased risk of venous thromboembolism (VTE) in lung fibrosis. Large-scale epidemiological data regarding…”
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Brain-derived neurotrophic factor mRNA downregulation produced by social isolation is blocked by intrahippocampal interleukin-1 receptor antagonist
Published in Neuroscience (01-01-2003)“…Manipulations that increase the expression of the pro-inflammatory cytokine interleukin-1β (IL-1β) in the hippocampus (e.g. peripheral administration of…”
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BDNF mRNA expression in rat hippocampus following contextual learning is blocked by intrahippocampal IL-1β administration
Published in Journal of neuroimmunology (01-10-2004)“…The present study examined the modulating effects of an intrahippocampal injection of interleukin-1β (IL-1β) on brain-derived neurotrophic factor (BDNF) mRNA…”
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Memory for context is impaired by a post context exposure injection of interleukin-1 beta into dorsal hippocampus
Published in Behavioural brain research (21-08-2002)“…Prior research has revealed that treatments that elevate the level of the pro-inflammatory cytokine IL-1β in the brain, if given after training, impair…”
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Microglia serve as a neuroimmune substrate for stress-induced potentiation of CNS pro-inflammatory cytokine responses
Published in Brain, behavior, and immunity (01-01-2007)“…Abstract Prior exposure to a stressor can potentiate CNS pro-inflammatory immune responses to a peripheral immune challenge. However, the neuroimmune…”
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Differential effects of neonatal handling on early life infection-induced alterations in cognition in adulthood
Published in Brain, behavior, and immunity (01-03-2007)“…Abstract We have previously demonstrated that bacterial infection ( Escherichia coli ) in neonatal rats is associated with impaired memory in a…”
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Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia
Published in Brain, behavior, and immunity (01-11-2008)“…Abstract Spinal proinflammatory cytokines are powerful pain-enhancing signals that contribute to pain following peripheral nerve injury (neuropathic pain)…”
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Peripheral infection and aging interact to impair hippocampal memory consolidation
Published in Neurobiology of aging (01-05-2006)“…We report that a peripheral injection of Escherichia coli produces both anterograde and retrograde amnesia in 24 month old, but not 3 month old rats for…”
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