Search Results - "SPROULL, Mary"

State-of-the-Art Advances in Radiation Biodosimetry for Mass Casualty Events Involving Radiation Exposure by Sproull, Mary, Camphausen, Kevin

“…With the possibility of large-scale terrorist attacks around the world, the need for modeling and development of new medical countermeasures for potential…”
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Novel Murine Biomarkers of Radiation Exposure Using An Aptamer-Based Proteomic Technology by Sproull, Mary, Shankavaram, Uma, Camphausen, Kevin

“…There is a need to identify new biomarkers of radiation exposure both for use in the development of biodosimetry blood diagnostics for radiation exposure and…”
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MGMT ProFWise: Unlocking a New Application for Combined Feature Selection and the Rank-Based Weighting Method to Link MGMT Methylation Status to Serum Protein Expression in Patients with Glioblastoma by Tasci, Erdal, Shah, Yajas, Jagasia, Sarisha, Zhuge, Ying, Shephard, Jason, Johnson, Margaret O, Elemento, Olivier, Joyce, Thomas, Chappidi, Shreya, Cooley Zgela, Theresa, Sproull, Mary, Mackey, Megan, Camphausen, Kevin, Krauze, Andra Valentina

“…Glioblastoma (GBM) is a fatal brain tumor with limited treatment options. O6-methylguanine-DNA-methyltransferase (MGMT) promoter methylation status is the…”
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Proteomic Biomarker Analysis of Serum from Japanese Field Mice (Apodemus Speciosus) Collected within the Fukushima Difficult-to-return Zone by Sproull, Mary, Hayes, Joshua, Ishiniwa, Hiroko, Nanba, Kenji, Shankavaram, Uma, Camphausen, Kevin, Johnson, Thomas E.

“…The environmental impact of the Fukushima Daiichi nuclear power plant accident is a source of ongoing concern as there is uncertainty regarding the effects of…”
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Glioblastoma survival is associated with distinct proteomic alteration signatures post chemoirradiation in a large-scale proteomic panel by Krauze, Andra Valentina, Sierk, Michael, Nguyen, Trinh, Chen, Qingrong, Yan, Chunhua, Hu, Ying, Jiang, William, Tasci, Erdal, Zgela, Theresa Cooley, Sproull, Mary, Mackey, Megan, Shankavaram, Uma, Meerzaman, Daoud, Camphausen, Kevin

“…Glioblastomas (GBM) are rapidly progressive, nearly uniformly fatal brain tumors. Proteomic analysis represents an opportunity for noninvasive GBM…”
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Microarray analysis identifies coding and non-coding RNA markers of liver injury in whole body irradiated mice by Aryankalayil, Molykutty J., Bylicky, Michelle A., Martello, Shannon, Chopra, Sunita, Sproull, Mary, May, Jared M., Shankardass, Aman, MacMillan, Laurel, Vanpouille-Box, Claire, Dalo, Juan, Scott, Kevin M. K., Norman Coleman, C.

“…Radiation injury from medical, accidental, or intentional sources can induce acute and long-term hepatic dysregulation, fibrosis, and cancer. This long-term…”
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Corrigendum: Glioblastoma survival is associated with distinct proteomic alteration signatures post chemoirradiation in a large-scale proteomic panel by Krauze, Andra Valentina, Sierk, Michael, Nguyen, Trinh, Chen, Qingrong, Yan, Chunhua, Hu, Ying, Jiang, William, Tasci, Erdal, Zgela, Theresa Cooley, Sproull, Mary, Mackey, Megan, Shankavaram, Uma, Meerzaman, Daoud, Camphausen, Kevin

“…[This corrects the article DOI: 10.3389/fonc.2023.1127645.]…”
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Revisiting Concurrent Radiation Therapy, Temozolomide, and the Histone Deacetylase Inhibitor Valproic Acid for Patients with Glioblastoma-Proteomic Alteration and Comparison Analysis with the Standard-of-Care Chemoirradiation by Krauze, Andra V, Zhao, Yingdong, Li, Ming-Chung, Shih, Joanna, Jiang, Will, Tasci, Erdal, Cooley Zgela, Theresa, Sproull, Mary, Mackey, Megan, Shankavaram, Uma, Tofilon, Philip, Camphausen, Kevin

“…Glioblastoma (GBM) is the most common brain tumor with an overall survival (OS) of less than 30% at two years. Valproic acid (VPA) demonstrated survival…”
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The Next Frontier in Health Disparities—A Closer Look at Exploring Sex Differences in Glioma Data and Omics Analysis, from Bench to Bedside and Back by Diaz Rosario, Maria, Kaur, Harpreet, Tasci, Erdal, Shankavaram, Uma, Sproull, Mary, Zhuge, Ying, Camphausen, Kevin, Krauze, Andra

“…Sex differences are increasingly being explored and reported in oncology, and glioma is no exception. As potentially meaningful sex differences are uncovered,…”
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Correlation of plasma FL expression with bone marrow irradiation dose by Sproull, Mary, Avondoglio, Dane, Kramp, Tamalee, Shankavaram, Uma, Camphausen, Kevin

“…Ablative bone marrow irradiation is an integral part of hematopoietic stem cell transplantation. These treatment regimens are based on classically held models…”
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Enhancement of in vitro and in vivo tumor cell radiosensitivity by valproic acid by Camphausen, Kevin, Cerna, David, Scott, Tamalee, Sproull, Mary, Burgan, William E., Cerra, Michael A., Fine, Howard, Tofilon, Philip J.

“…Valproic acid (VA) is a well‐tolerated drug used to treat seizure disorders and has recently been shown to inhibit histone deacetylase (HDAC). Because HDAC…”
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Enhancement of Xenograft Tumor Radiosensitivity by the Histone Deacetylase Inhibitor MS-275 and Correlation with Histone Hyperacetylation by CAMPHAUSEN, Kevin, SCOTT, Tamalee, SPROULL, Mary, TOFILON, Philip J

“…Purpose: Histone deacetylase (HDAC) inhibitors are undergoing clinical evaluation in cancer therapy. Because HDAC modulation has been shown to enhance the…”
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Influence of in vivo Growth on Human Glioma Cell Line Gene Expression: Convergent Profiles under Orthotopic Conditions by Camphausen, Kevin, Purow, Benjamin, Sproull, Mary, Scott, Tamalee, Ozawa, Tomoko, Deen, Dennis F., Tofilon, Philip J., Cleaver, James E.

“…Defining the molecules that regulate tumor cell survival is an essential prerequisite for the development of targeted approaches to cancer treatment. Whereas…”
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Urine Analysis and Protein Networking Identify Met as a Marker of Metastatic Prostate Cancer by RUSSO, Andrea L, JEDLICKA, Kimberly, DAHUT, William, CITRIN, Deborah, BOTTARO, Donald P, ALBERT, Paul S, TOFILON, Philip J, CAMPHAUSEN, Kevin, WERNICK, Meredith, MCNALLY, Debbie, KIRK, Melissa, SPROULL, Mary, SMITH, Sharon, SHANKAVARAM, Uma, KAUSHAL, Aradhana, FIGG, William D

“…Purpose: Metastatic prostate cancer is a major cause of death of men in the United States. Expression of met, a receptor tyrosine kinase, has been associated…”
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High throughput evaluation of gamma-H2AX by Avondoglio, Dane, Scott, Tamalee, Kil, Whoon Jong, Sproull, Mary, Tofilon, Philip J, Camphausen, Kevin

“…The DNA double-strand break (DSB) is the primary lethal lesion after therapeutic radiation. Thus, the development of assays to detect and to quantitate these…”
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Urinary VEGF and MMP Levels As Predictive Markers of 1-Year Progression-Free Survival in Cancer Patients Treated With Radiation Therapy: A Longitudinal Study of Protein Kinetics Throughout Tumor Progression and Therapy by CHAN, Linda W, MOSES, Marsha A, GOLEY, Elizabeth, SPROULL, Mary, MUANZA, Thierry, COLEMAN, C. Norman, FIGG, William D, ALBERT, Paul S, MENARD, Cynthia, CAMPHAUSEN, Kevin

“…To determine the predictive value of urinary levels of two angiogenic factors, vascular endothelial growth factor (VEGF) and matrix metalloproteinase (MMPs),…”
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Orthotopic growth of human glioma cells quantitatively and qualitatively influences radiation-induced changes in gene expression by CAMPHAUSEN, Kevin, PUROW, Benjamin, SPROULL, Mary, SCOTT, Tamalee, OZAWA, Tomoko, DEEN, Dennis F, TOFILON, Philip J

“…The effect of radiation on gene expression has been most frequently studied using tissue culture models. To determine the influence of experimental growth…”
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Computational modeling of first responders' willingness to accept radiation exposure during radiological or nuclear events by Sproull, Mary, Rebmann, Terri, Turner, Austin, Charney, Rachel, Petricoin, Emmanuel, Koblentz, Gregory D, Kennedy, William G

“…Since the events of 9/11, a concerted interagency effort has been undertaken to create comprehensive emergency planning and preparedness strategies for the…”
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In vivo tumor imaging in mice with near-infrared labeled endostatin by Citrin, Deborah, Lee, Andrew K, Scott, Tamalee, Sproull, Mary, Ménard, Cynthia, Tofilon, Philip J, Camphausen, Kevin

“…Endostatin is a potent inhibitor of angiogenesis currently in phase I clinical trials. Imaging technologies that use near-infrared fluorescent probes are well…”
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Comparison of Proteomic Biodosimetry Biomarkers Across Five Different Murine Strains by Sproull, Mary, Shankavaram, Uma, Camphausen, Kevin

“…In the event of a radiological or nuclear attack, advanced clinical countermeasures are needed for screening and medical management of the exposed population…”
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