Search Results - "SPRATT, Neil J"
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"Are we there yet?" expectations and experiences with lower limb robotic exoskeletons: a qualitative evaluation of the therapist perspective
Published in Disability and rehabilitation (27-02-2024)“…Further innovation of design features, marketing, and cost are needed to enhance ongoing development and integration. Routine clinical implementation of lower…”
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Thresholds for infarction vary between gray matter and white matter in acute ischemic stroke: A CT perfusion study
Published in Journal of cerebral blood flow and metabolism (01-03-2019)“…We aimed to investigate optimal perfusion thresholds defining ischemic core and penumbra for hemispheric-cortical gray matter (GM) and subcortical white matter…”
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3
Perfusion computed tomography to assist decision making for stroke thrombolysis
Published in Brain (London, England : 1878) (01-07-2015)“…The use of perfusion imaging to guide selection of patients for stroke thrombolysis remains controversial because of lack of supportive phase three clinical…”
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An online survey of informal caregivers' unmet needs and associated factors
Published in PloS one (10-12-2020)“…The purpose of this study was to assess the frequency of unmet needs of carers among a convenience sample of carers, and the participant factors associated…”
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5
Collateral assessment on magnetic resonance imaging/angiography up to 30 hours after stroke onset
Published in PloS one (03-09-2024)“…We aimed to validate hyperintense vessel sign (HVS) on FLAIR imaging or posterior cerebral artery (PCA) laterality on MR angiography beyond 4.5 hours after…”
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Permeability Measures Predict Hemorrhagic Transformation after Ischemic Stroke
Published in Annals of neurology (01-09-2020)“…Objective We sought to examine the diagnostic utility of existing predictors of any hemorrhagic transformation (HT) and compare them with new perfusion imaging…”
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7
Physiotherapy using a free-standing robotic exoskeleton for patients with spinal cord injury: a feasibility study
Published in Journal of neuroengineering and rehabilitation (25-12-2021)“…Evidence is emerging for the use of overground lower limb robotic exoskeletons in the rehabilitation of people with spinal cord injury (SCI), with suggested…”
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Arterial Spin Labeling Versus Bolus-Tracking Perfusion in Hyperacute Stroke
Published in Stroke (1970) (2014)“…Arterial spin labeling (ASL) is a perfusion magnetic resonance imaging (MRI) technique that does not require contrast administration and thus may be more…”
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Evaluation of an online intervention for improving stroke survivors' health-related quality of life: A randomised controlled trial
Published in PLoS medicine (19-04-2022)“…The aim of this trial was to evaluate the effectiveness of an online health behaviour change intervention-Prevent 2nd Stroke (P2S)-at improving health-related…”
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Exploring the relationship between ischemic core volume and clinical outcomes after thrombectomy or thrombolysis
Published in Neurology (16-07-2019)“…OBJECTIVETo assess whether complete reperfusion after IV thrombolysis (IVT-R) would result in similar clinical outcomes compared to complete reperfusion after…”
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Impairments, and physical design and culture of a rehabilitation unit influence stroke survivor activity: qualitative analysis of rehabilitation staff perceptions
Published in Disability and rehabilitation (18-12-2022)“…This study aimed to investigate rehabilitation staff perceptions of factors influencing stroke survivor activity outside of dedicated therapy time for the…”
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"This is our life now. Our new normal": A qualitative study of the unmet needs of carers of stroke survivors
Published in PloS one (08-05-2019)“…Many stroke survivors require care from informal carers such as family members and friends who may experience adverse impacts. This study aimed to…”
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Short-duration hypothermia completed prior to reperfusion prevents intracranial pressure elevation following ischaemic stroke in rats
Published in Scientific reports (16-11-2021)“…Reperfusion therapies re-establish blood flow after arterial occlusion and improve outcome for ischaemic stroke patients. Intracranial pressure (ICP) elevation…”
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Relationship Between Collateral Status, Contrast Transit, and Contrast Density in Acute Ischemic Stroke
Published in Stroke (1970) (01-03-2016)“…Collateral circulation is recognized to influence the life expectancy of the ischemic penumbra in acute ischemic stroke. The best method to quantify collateral…”
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Frequent, short bouts of light-intensity exercises while standing decreases systolic blood pressure: Breaking Up Sitting Time after Stroke (BUST-Stroke) trial
Published in International journal of stroke (01-12-2018)“…Background Stroke survivors sit for long periods each day. Uninterrupted sitting is associated with increased risk of cardiovascular disease. Breaking up…”
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CSF Secretion Is Not Altered by NKCC1 Nor TRPV4 Antagonism in Healthy Rats
Published in Brain sciences (24-08-2021)“…Background: Cerebrospinal fluid (CSF) secretion can be targeted to reduce elevated intracranial pressure (ICP). Sodium-potassium-chloride cotransporter 1…”
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Sonothrombolysis with BR38 Microbubbles Improves Microvascular Patency in a Rat Model of Stroke
Published in PloS one (14-04-2016)“…Early recanalization of large cerebral vessels in ischemic stroke is associated with improved clinical outcome, however persisting hypoperfusion leads to poor…”
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Cerebrospinal fluid is drained primarily via the spinal canal and olfactory route in young and aged spontaneously hypertensive rats
Published in Fluids and barriers of the CNS (06-06-2014)“…Many aspects of CSF dynamics are poorly understood due to the difficulties involved in quantification and visualization. In particular, there is debate…”
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Multimodal Computed Tomography Increases the Detection of Posterior Fossa Strokes Compared to Brain Non-contrast Computed Tomography
Published in Frontiers in neurology (20-11-2020)“…Multimodal computed tomography (mCT) (non-contrast CT, CT angiography, and CT perfusion) is not routinely used to assess posterior fossa strokes. We described…”
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Ultra-Short Duration Hypothermia Prevents Intracranial Pressure Elevation Following Ischaemic Stroke in Rats
Published in Frontiers in neurology (20-09-2021)“…There is a transient increase in intracranial pressure (ICP) 18–24 h after ischaemic stroke in rats, which is prevented by short-duration hypothermia using…”
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