Search Results - "SPOERRI, P. E"

Proliferating endothelial cell-specific expression of IGF-I receptor ribozyme inhibits retinal neovascularization by SHAW, L. C, PAN, H, AFZAL, A, CALZI, S. L, SPOERRI, P. E, SULLIVAN, S. M, GRANT, M. B

“…Insulin-like growth factor-I (IGF-I) and its receptor (IGF-IR) are essential for normal ocular development and are expressed in numerous ocular cell types…”
Get full text

Reduction in Preretinal Neovascularization by Ribozymes That Cleave the A2B Adenosine Receptor mRNA by Afzal, A, Shaw, L C, Caballero, S, Spoerri, P E, Lewin, A S, Zeng, D, Belardinelli, L, Grant, M B

“…ABSTRACT—Adenosine modulates a variety of cellular functions by interacting with specific cell surface G protein–coupled receptors (A1, A2A, A2B, and A3) and…”
Get full text

Adenosine Receptor Activation Induces Vascular Endothelial Growth Factor in Human Retinal Endothelial Cells by Grant, Maria B, Tarnuzzer, Roy W, Caballero, Sergio, Ozeck, Mark J, Davis, Margaret I, Spoerri, Polyxenie E, Feoktistov, Igor, Biaggioni, Italo, Shryock, John C, Belardinelli, Luiz

“…Adenosine, released in increased amounts by hypoxic tissues, is thought to be an angiogenic factor that links altered cellular metabolism caused by oxygen…”
Get full text

Neurotrophic effects of GABA in cultures of embryonic chick brain and retina by Spoerri, P E

“…The present study examined whether GABA treatments would affect the growth and development of embryonic chick cortical and retinal neurons in culture…”
Get more information

Expression of IGF-I, IGF-I receptor and IGF binding proteins -1, -2, -3, -4 and -5 in human atherectomy specimens by Grant, M.B, Wargovich, T.J, Ellis, E.A, Tarnuzzer, R, Caballero, S, Estes, K, Rossing, M, Spoerri, P.E, Pepine, C

“…The molecular and cellular processes that induce rapid atherosclerotic plaque progression in patients with unstable angina and initiate restenosis following…”
Get full text

Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization by Grant, Maria B, Scott, Edward W, May, W. Stratford, Caballero, Sergio, Brown, Gary A. J, Guthrie, Steven M, Mames, Robert N, Byrne, Barry J, Vaught, Timothy, Spoerri, Polyxenie E, Peck, Ammon B

“…Adults maintain a reservoir of hematopoietic stem cells that can enter the circulation to reach organs in need of regeneration. We developed a novel model of…”
Get full text

Insulin-like growth factor: receptor and binding proteins in human retinal endothelial cell cultures of diabetic and non-diabetic origin by Spoerri, P.E., Ellis, E.A., Tarnuzzer, R.W., Grant, M.B.

“…Human retinal endothelial cell (HREC) cultures of diabetic and non-diabetic origin were examined for the production of insulin-like growth factor I (IGF-I),…”
Get full text

Interaction of ganglioside GM1 with the B subunit of cholera toxin modulates intracellular free calcium in sensory neurons by Milani, D, Minozzi, M C, Petrelli, L, Guidolin, D, Skaper, S D, Spoerri, P E

“…The B subunit of cholera toxin, which binds specifically to GM1 ganglioside on cell surfaces, has previously been shown to modulate intracellular calcium…”
Get more information

Expression of IGF-1, IGF-1 receptor and TGF-β following balloon angioplasty in atherosclerotic and normal rabbit iliac arteries: An immunocytochemical study by Grant, Maria B, Wargovich, Thomas J, Bush, David M, Player, Denifield W, Caballero, Sergio, Foegh, Marie, Spoerri, Polyxenie E

“…Growth factors have been implicated in the pathogenesis of restenosis (myointimal hyperplasia after coronary interventions). In this study, we examined the…”
Get full text

Cytoskeletal elements regulate the distribution of nerve growth factor receptors in PC12 cells by Spoerri, P E, Roisen, F J

“…Nerve growth factor receptor (NGFR)-like immunoreactivity (IR) was studied in PC12 cells treated for 96 hr with NGF (40 ng/ml), using immunogold labeling and…”
Get more information

Fibronectin fragments modulate human retinal capillary cell proliferation and migration by GRANT, M. B, CABALLERO, S, BUSH, D. M, SPOERRI, P. E

“…Capillary morphogenesis involves cell-cell and cell-matrix interactions. Proteases elaborated by capillary cells modify the extracellular matrix (ECM) to…”
Get full text

Colocalization of low- and high-affinity NGF receptors on PC12 cells, C6 glioma cells and dorsal root ganglion neurons by Spoerri, P E, Petrelli, L, Guidolin, D, Skaper, S D

“…The biological responsiveness of neural cells to nerve growth factor (NGF) appears to require expression and ligand binding to both the low-affinity NGF…”
Get more information

Inhibition of conditioned media-mediated neuritogenesis of sensory ganglia by monoclonal antibodies to GM1 ganglioside by Spoerri, P E, Rapport, M M, Mahadik, S P, Roisen, F J

“…The monosialoganglioside GM1 can potentiate the neuritogenic activity of media conditioned by several cell types: neonatal glia, C6 glioma, embryonic chick…”
Get more information

Ganglioside potentiation of NGF-independent trophic agents on sensory ganglia by Spoerri, P E, Roisen, F J

“…The ability of gangliosides to potentiate nerve growth factor (NGF)-independent trophic agents was determined by examining the capacity of an exogenous mixture…”
Get more information

Calcium regulation of neuronal differentiation: the role of calcium in GM1-mediated neuritogenesis by Spoerri, P E, Dozier, A K, Roisen, F J

“…Cultures of mouse Neuro-2a neuroblastoma cells treated with 3-6 mM extracellular Ca2+ exhibited enhanced neurite extension characterized by increased neurite…”
Get more information

Matrix metalloproteinase expression in human retinal microvascular cells by GRANT, M. B, CABALLERO, S, TARNUZZER, R. W, BASS, K. E, LJUBIMOV, A. V, SPOERRI, P. E, GALARDY, R. E

“…The degree of hyperglycemia correlates with the development of diabetic retinopathy. We investigated the effect of glucose on the expression of matrix…”
Get full text

Photoreceptor cell development in vitro: influence of pigment epithelium conditioned medium on outer segment differentiation by Spoerri, P E, Ulshafer, R J, Ludwig, H C, Allen, C B, Kelley, K C

Get more information

Taurine-induced neuronal differentiation: the influence of calcium and the ganglioside GM1 by Spoerri, P E, Caple, C G, Roisen, F J

“…Taurine-induced differentiation was examined in the murine neuroblastoma Neuro-2a cell line in the presence or absence of the monosialoganglioside GM1 and…”
Get more information

K+ potentiation of non-NGF mediated neurite outgrowth in sensory ganglia by Spoerri, P E, Müller, G, Markakis, E

Get more information

Fibronectin fragments modulate human retinal capillary cell proliferation and migration by M B Grant, S Caballero, D M Bush, P E Spoerri

“…Fibronectin fragments modulate human retinal capillary cell proliferation and migration. M B Grant , S Caballero , D M Bush and P E Spoerri Department of…”
Get full text