Search Results - "SPITZER, M"

The use of HCT and/or ACE inhibitors significantly increases the risk of non-melanotic skin cancer in the periocular region by Mehlan, Juliane, Ueberschaar, Julian, Hagenström, K., Garbe, C., Spitzer, M. S., Druchkiv, V., Schuettauf, F.

“…Background/Aims To investigate a possible association between the use of hydrochlorothiazide (HCT) and/or angiotensin-converting enzyme inhibitors (ACE…”
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Identification of novel functional inhibitors of acid sphingomyelinase by Kornhuber, Johannes, Muehlbacher, Markus, Trapp, Stefan, Pechmann, Stefanie, Friedl, Astrid, Reichel, Martin, Mühle, Christiane, Terfloth, Lothar, Groemer, Teja W, Spitzer, Gudrun M, Liedl, Klaus R, Gulbins, Erich, Tripal, Philipp

“…We describe a hitherto unknown feature for 27 small drug-like molecules, namely functional inhibition of acid sphingomyelinase (ASM). These entities named…”
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PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex by Link, Stephanie, Spitzer, Ramona M. M., Sana, Maryam, Torrado, Mario, Völker-Albert, Moritz C., Keilhauer, Eva C., Burgold, Thomas, Pünzeler, Sebastian, Low, Jason K. K., Lindström, Ida, Nist, Andrea, Regnard, Catherine, Stiewe, Thorsten, Hendrich, Brian, Imhof, Axel, Mann, Matthias, Mackay, Joel P., Bartkuhn, Marek, Hake, Sandra B.

“…Chromatin structure and function is regulated by reader proteins recognizing histone modifications and/or histone variants. We recently identified that PWWP2A…”
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Metabolomics as read-across tool: An example with 3-aminopropanol and 2-aminoethanol by Sperber, S., Wahl, M., Berger, F., Kamp, H., Lemke, O., Starck, V., Walk, T., Spitzer, M., Ravenzwaay, B.v

“…Read-across and grouping is one of the most commonly used alternative approaches for data gap filling in registrations submitted under the REACH Regulation as…”
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How To Optimize Shape-Based Virtual Screening: Choosing the Right Query and Including Chemical Information by Kirchmair, Johannes, Distinto, Simona, Markt, Patrick, Schuster, Daniela, Spitzer, Gudrun M, Liedl, Klaus R, Wolber, Gerhard

“…Shape-based molecular similarity approaches have been established as important and popular virtual screening techniques. Recent applications have shown…”
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Multivalent binding of PWWP2A to H2A.Z regulates mitosis and neural crest differentiation by Pünzeler, Sebastian, Link, Stephanie, Wagner, Gabriele, Keilhauer, Eva C, Kronbeck, Nina, Spitzer, Ramona MM, Leidescher, Susanne, Markaki, Yolanda, Mentele, Edith, Regnard, Catherine, Schneider, Katrin, Takahashi, Daisuke, Kusakabe, Masayuki, Vardabasso, Chiara, Zink, Lisa M, Straub, Tobias, Bernstein, Emily, Harata, Masahiko, Leonhardt, Heinrich, Mann, Matthias, Rupp, Ralph AW, Hake, Sandra B

“…Replacement of canonical histones with specialized histone variants promotes altering of chromatin structure and function. The essential histone variant H2A.Z…”
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Z-suture: a new knotless technique for transscleral suture fixation of intraocular implants by Szurman, P, Petermeier, K, Aisenbrey, S, Spitzer, M S, Jaissle, G B

“…The presented Z-suture is a simple, rapid and safe knotless technique that facilitates transscleral suture fixation of various intraocular implants in the…”
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Quantifying Speech Rhythm Abnormalities in the Dysarthrias by Liss, Julie M, White, Laurence, Mattys, Sven L, Lansford, Kaitlin, Lotto, Andrew J, Spitzer, Stephanie M, Caviness, John N

“…Purpose: In this study, the authors examined whether rhythm metrics capable of distinguishing languages with high and low temporal stress contrast also can…”
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Mathematical Knowledge for Teaching in Planning and Evaluating Instruction: What Can Preservice Teachers Learn? by Morris, Anne K., Hiebert, James, Spitzer, Sandy M.

“…The goal of this study is to uncover the successes and challenges that preservice teachers are likely to experience as they unpack lesson-level mathematical…”
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Metabolomics as read-across tool: A case study with phenoxy herbicides by van Ravenzwaay, B., Sperber, S., Lemke, O., Fabian, E., Faulhammer, F., Kamp, H., Mellert, W., Strauss, V., Strigun, A., Peter, E., Spitzer, M., Walk, T.

“…New technologies, such as metabolomics, can address chemical grouping and read across from a biological perspective. In a virtual case study, we selected MCPP…”
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Three-Dimensional Mechanics, Kinematics, and Morphology of the Knee Viewed in Virtual Reality by Eckhoff, Donald G, Bach, Joel M, Spitzer, Victor M, Reinig, Karl D, Bagur, Michelle M, Baldini, Todd H, Flannery, Nicolas M.P

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A Cognitive Neuroscience View of Schizophrenic Thought Disorder by Spitzer, Manfred

“…The experimental association psychology approach to mental associations has been the conceptual background for the concept of schizophrenia. Cognitive…”
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Smoking cessation behaviors three months following acute insular damage from stroke by Abdolahi, Amir, Williams, Geoffrey C, Benesch, Curtis G, Wang, Henry Z, Spitzer, Eric M, Scott, Bryan E, Block, Robert C, van Wijngaarden, Edwin

“…Abstract Background Recent evidence suggests that the insular cortex may play an important role in cognitive and emotional processes that facilitate drug use…”
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Three-dimensional mechanics, kinematics, and morphology of the knee viewed in virtual reality by ECKHOFF, Donald G, BACH, Joel M, SPITZER, Victor M, REINIG, Karl D, BAGUR, Michelle M, BALDINI, Todd H, FLANNERY, Nicolas M. P

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Antiproliferative and cytotoxic properties of bevacizumab on different ocular cells by Spitzer, M S, Wallenfels-Thilo, B, Sierra, A, Yoeruek, E, Peters, S, Henke-Fahle, S, Bartz-Schmidt, K U, Szurman, P

“…Aim: To evaluate the antiproliferative and cytotoxic properties of bevacizumab, a monoclonal antibody against vascular endothelial growth factor (VEGF), on…”
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Neural Substrates of Phonemic Perception by Liebenthal, Einat, Binder, Jeffrey R., Spitzer, Stephanie M., Possing, Edward T., Medler, David A.

“…The temporal lobe in the left hemisphere has long been implicated in the perception of speech sounds. Little is known, however, regarding the specific function…”
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Cleavage entropy as quantitative measure of protease specificity by Fuchs, Julian E, von Grafenstein, Susanne, Huber, Roland G, Margreiter, Michael A, Spitzer, Gudrun M, Wallnoefer, Hannes G, Liedl, Klaus R

“…A purely information theory-guided approach to quantitatively characterize protease specificity is established. We calculate an entropy value for each protease…”
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The Protein Data Bank (PDB), Its Related Services and Software Tools as Key Components for In Silico Guided Drug Discovery by Kirchmair, Johannes, Markt, Patrick, Distinto, Simona, Schuster, Daniela, Spitzer, Gudrun M, Liedl, Klaus R, Langer, Thierry, Wolber, Gerhard

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Dynamic regulation of phenylalanine hydroxylase by simulated redox manipulation by Fuchs, Julian E, Huber, Roland G, von Grafenstein, Susanne, Wallnoefer, Hannes G, Spitzer, Gudrun M, Fuchs, Dietmar, Liedl, Klaus R

“…Recent clinical studies revealed increased phenylalanine levels and phenylalanine to tyrosine ratios in patients suffering from infection, inflammation and…”
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Refractive errors, visual impairment, and the use of low-vision devices in albinism in Malawi by Schulze Schwering, M., Kumar, N., Bohrmann, D., Msukwa, G., Kalua, K., Kayange, P., Spitzer, M. S.

“…Background This study focuses on the refractive implications of albinism in Malawi, which is mostly associated with the burden of visual impairment. The main…”
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