Search Results - "SPIRO, R. C"

Biosynthetic and functional properties of an Arg-Gly-Asp-directed receptor involved in human melanoma cell attachment to vitronectin, fibrinogen, and von Willebrand factor by Cheresh, D A, Spiro, R C

“…M21 human melanoma cells express an Arg-Gly-Asp-directed adhesion receptor composed of noncovalently associated alpha and beta chains. To establish the…”
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An osteoconductive collagen/hyaluronate matrix for bone regeneration by Liu, Lin-Shu, Thompson, Andrea Y., Heidaran, Mohammad A., Poser, James W., Spiro, Robert C.

“…A new type of collagen-hyaluronate (COL/HA) matrix was synthesized by cross-linking collagen fibers with modified hyaluronate polymers bearing active formyl…”
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Novel formulation of fibroblast growth factor-2 in a hyaluronan gel accelerates fracture healing in nonhuman primates by Radomsky, M L, Aufdemorte, T B, Swain, L D, Fox, W C, Spiro, R C, Poser, J W

“…Recent advances in understanding the biology of fracture healing and the availability of specific macromolecules has resulted in the development of novel…”
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Potential role of fibroblast growth factor in enhancement of fracture healing by Radomsky, M L, Thompson, A Y, Spiro, R C, Poser, J W

“…Fibroblast growth factors are present in significant amounts in bone and several studies have suggested that they may be involved in normal fracture healing…”
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Correlation of chondroitin sulfate proteoglycan expression on proliferating brain capillary endothelial cells with the malignant phenotype of astroglial cells by SCHRAPPE, M, KLIER, F. G, SPIRO, R. C, WALTZ, T. A, REISFELD, R. A, GLADSON, C. L

“…Human glioblastomas (five of five), the most malignant astroglial-derived tumors, specifically express a chondroitin sulfate proteoglycan that is recognized by…”
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Uncoupling of Chondroitin Sulfate Glycosaminoglycan Synthesis by Brefeldin A by Spiro, Robert C., Freeze, Hudson H., Sampath, Deepak, Garcia, Joseph A.

“…Brefeldin A has dramatic, well-documented, effects on the structural and functional organization of the Golgi complex. We have examined the effects of…”
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A human brain glycoprotein related to the mouse cell adhesion molecule L1 by Wolff, J M, Frank, R, Mujoo, K, Spiro, R C, Reisfeld, R A, Rathjen, F G

“…We have employed monoclonal antibody 5G3, an antibody used to label human tumor cells of neural origin (Mujoo, K., Spiro, R.C., and Reisfeld, R. A. (1986) J…”
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Characterization of a unique glycoprotein antigen expressed on the surface of human neuroblastoma cells by Mujoo, K, Spiro, R C, Reisfeld, R A

“…In order to develop a molecular probe to delineate chemical and biological characteristics of human neuroblastoma cells, a murine monoclonal antibody (Mab 5G3)…”
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Post-translational addition of chondroitin sulfate glycosaminoglycans. Role of N-linked oligosaccharide addition, trimming, and processing by SPIRO, R. C, CASTEEL, H. E, LAUFER, D. M, REISFELD, R. A, HARPER, J. R

“…A melanoma proteoglycan model system has been used to examine the role of core protein asparagine-linked (N-linked) oligosaccharides in the transport and…”
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The invariant chain is a phosphorylated subunit of class II molecules by Spiro, RC, Quaranta, V

“…The phosphorylation of the MHC, class II-associated invariant chain (gamma) is demonstrated in human B-lymphoblastoid, melanoma, and histiocytic lymphoma cell…”
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Role of transforming growth factor beta and decorin in controlling fibrosis by Harper, J R, Spiro, R C, Gaarde, W A, Tamura, R N, Pierschbacher, M D, Noble, N A, Stecker, K K, Border, W A

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Inductive activity of recombinant human growth and differentiation factor-5 by Spiro, R C, Liu, L, Heidaran, M A, Thompson, A Y, Ng, C K, Pohl, J, Poser, J W

“…Growth and differentiation factor-5 (GDF-5) is a divergent member of the transforming growth factor-beta/bone morphogenetic protein (BMP) superfamily that is…”
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Inhibition of post-translational modification and surface expression of a melanoma-associated chondroitin sulfate proteoglycan by diethylcarbamazine or ammonium chloride by Spiro, R C, Parsons, W G, Perry, S K, Caulfield, J P, Hein, A, Reisfeld, R A, Harper, J R, Austen, K F, Stevens, R L

“…Cultured human melanoma M21 cells were treated with diethylcarbamazine (DEC), an inhibitor of proteoglycan biosynthesis in rat chondrosarcoma cells, to examine…”
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Spreading and focal contact formation of human melanoma cells in response to the stimulation of both melanoma-associated proteoglycan (NG2) and alpha 4 beta 1 integrin by Iida, J, Meijne, A M, Spiro, R C, Roos, E, Furcht, L T, McCarthy, J B

“…In this study, we evaluated the potential role for a specific melanoma-associated chondroitin sulfate proteoglycan core protein, termed NG2, to collaborate…”
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Spinal fusion with recombinant human growth and differentiation factor‐5 combined with a mineralized collagen matrix by Spiro, Robert C., Thompson, Andrea Y., Poser, James W.

“…The availability of recombinant osteoinductive growth factors and new osteoconductive matrices offers an alternative to the use of autogenous bone (autograft)…”
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Functional association of class II antigens with cell surface binding of Epstein-Barr virus by Reisert, PS, Spiro, RC, Townsend, PL, Stanford, SA, Sairenji, T, Humphreys, RE

“…A functional role of class II antigen in the binding of Epstein-Barr virus (EBV) was deduced from the study of membrane proteins on Jijoye, an EBV receptor…”
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Post-translational processing of the glycoproteins of lymphocytic choriomeningitis virus by Wright, K E, Spiro, R C, Burns, J W, Buchmeier, M J

“…Intracellular events in the synthesis, glycosylation, and transport of the lymphocytic choriomeningitis virus (LCMV) glycoproteins have been examined. We have…”
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Kinetics of Ii synthesis, processing, and turnover in n-butyrate- treated Burkitt's lymphoma cell lines which express or do not express class II antigens and in hairy leukemic cells by Spiro, RC, Sairenji, T, Humphreys, RE

“…We have sought to understand the role of the electrophoretically invariant chain (Ii) in class II antigen functions, particularly in certain transformed cells…”
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Epstein-Barr virus infections in hairy cell leukemia patients in the presence of complement-dependent neutralizing antibody by SAIRENJI, T, SULLIVAN, J. L, SAKAMOTO, K, SPIRO, R. C, KATAYAMA, I, HUMPHREYS, R. E

“…Immune system status was characterized in patients with hairy cell leukemia (HCL) with respect to explaining their chronic or recurrent infections with…”
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Analysis of transformation with Epstein-Barr virus and phenotypic characteristics of lymphoblastoid cell lines established from patients with hairy cell leukemia by Sairenji, T, Spiro, R C, Reisert, P S, Paquin, L, Sakamoto, K, Shibuya, A, Sullivan, J L, Katayama, I, Humphreys, R E

“…In order to assess the role of Epstein-Barr virus (EBV) in patients with hairy cell leukemia (HCL), we have sought to characterize 1) the ability of EBV to…”
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