Search Results - "SPILLER, Fernando"

Targeting nitric oxide as a key modulator of sepsis, arthritis and pain by Spiller, Fernando, Oliveira Formiga, Rodrigo, Fernandes da Silva Coimbra, Jonathan, Alves-Filho, Jose Carlos, Cunha, Thiago Mattar, Cunha, Fernando Queiroz

“…Nitric oxide (NO) is produced by enzymatic activity of neuronal (nNOS), endothelial (eNOS), and inducible nitric oxide synthase (iNOS) and modulates a broad…”
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p -Cymene and Rosmarinic Acid Ameliorate TNBS-Induced Intestinal Inflammation Upkeeping ZO-1 and MUC-2: Role of Antioxidant System and Immunomodulation by Formiga, Rodrigo de Oliveira, Alves Júnior, Edvaldo Balbino, Vasconcelos, Roseane Carvalho, Guerra, Gerlane Coelho Bernardo, Antunes de Araújo, Aurigena, Carvalho, Thaís Gomes de, Garcia, Vinícius Barreto, de Araújo Junior, Raimundo Fernandes, Gadelha, Francisco Allysson Assis Ferreira, Vieira, Giciane Carvalho, Sobral, Marianna Vieira, Barbosa Filho, José Maria, Spiller, Fernando, Batista, Leônia Maria

“…-Cymene ( -C) and rosmarinic acid (RA) are secondary metabolites that are present in medicinal herbs and Mediterranean spices that have promising…”
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Regulation of chemokine receptor by Toll-like receptor 2 is critical to neutrophil migration and resistance to polymicrobial sepsis by Alves-Filho, Jose C, Freitas, Andressa, Souto, Fabricio O, Spiller, Fernando, Paula-Neto, Heitor, Silva, Joao S, Gazzinelli, Ricardo T, Teixeira, Mauro M, Ferreira, Sergio H, Cunha, Fernando Q

“…Patients with sepsis have a marked defect in neutrophil migration. Here we identify a key role of Toll-like receptor 2 (TLR2) in the regulation of neutrophil…”
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Murine Red Blood Cells Lack Ligands for B Cell Siglecs, Allowing Strong Activation by Erythrocyte Surface Antigens by Spiller, Fernando, Nycholat, Corwin M, Kikuchi, Chika, Paulson, James C, Macauley, Matthew S

“…CD22 and sialic acid-binding Ig-like lectin (Siglec)-G are members of the Siglec family of inhibitory coreceptors expressed on B cells that participate in…”
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α1-Acid Glycoprotein Decreases Neutrophil Migration and Increases Susceptibility to Sepsis in Diabetic Mice by SPILLER, Fernando, CARLOS, Daniela, SOUTO, Fabricio O, DE FREITAS, Andressa, SOARES, Fernanda S, VIEIRA, Silvio M, PAULA, Francisco J. A, ALVES-FILHO, Jose C, CUNHA, Fernando Q

“…The mechanisms underlying immune deficiency in diabetes are largely unknown. In the present study, we demonstrate that diabetic mice are highly susceptible to…”
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Antibiotic-Induced Pathobiont Dissemination Accelerates Mortality in Severe Experimental Pancreatitis by Soares, Fernanda S, Amaral, Flávia C, Silva, Natália L C, Valente, Matheus R, Santos, Lorena K R, Yamashiro, Lívia H, Scheffer, Mara C, Castanheira, Fernanda V E S, Ferreira, Raphael G, Gehrke, Laura, Alves-Filho, José C, Silva, Luciano P, Báfica, André, Spiller, Fernando

“…Although antibiotic-induced dysbiosis has been demonstrated to exacerbate intestinal inflammation, it has been suggested that antibiotic prophylaxis may be…”
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Glucose homeostasis in two degrees of sepsis lethality induced by caecum ligation and puncture in mice by Ferreira, Francielle B. D., Santos, Cristiane, Bruxel, Maciel A., Nunes, Everson A., Spiller, Fernando, Rafacho, Alex

“…Summary Sepsis is associated with high mortality. Both critically ill humans and animal models of sepsis exhibit changes in their glucose homeostasis, that is,…”
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Down-regulation of CXCR2 on Neutrophils in Severe Sepsis Is Mediated by Inducible Nitric Oxide Synthase-derived Nitric Oxide by Rios-Santos, Fabricio, Alves-Filho, Jose C, Souto, Fabricio Oliveira, Spiller, Fernando, Freitas, Andressa, Lotufo, Celina Monteiro C, Soares, Milena Botelho Pereira, dos Santos, Ricardo Ribeiro, Teixeira, Mauro M, de Queiroz Cunha, Fernando

“…The failure of neutrophils to migrate to an infection focus during severe sepsis is an important determinant of the inability of a host to deal with an…”
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MyD88-, but not Nod1- and/or Nod2-deficient mice, show increased susceptibility to polymicrobial sepsis due to impaired local inflammatory response by Sônego, Fabiane, Castanheira, Fernanda V S, Czaikoski, Paula G, Kanashiro, Alexandre, Souto, Fabricio O, França, Rafael O, Nascimento, Daniele C, Freitas, Andressa, Spiller, Fernando, Cunha, Larissa D, Zamboni, Dario S, Alves-Filho, José C, Cunha, Fernando Q

“…Pathogen recognition and triggering of the inflammatory response following infection in mammals depend mainly on Toll-like and Nod-like receptors. Here, we…”
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Anti-inflammatory effects of red pepper (Capsicum baccatum) on carrageenan- and antigen-induced inflammation by Spiller, Fernando, Alves, Márcia K., Vieira, Sílvio M., Carvalho, Toni A., Leite, Carlos E., Lunardelli, Adroaldo, Poloni, José A., Cunha, Fernando Q., de Oliveira, Jarbas R.

“…Inflammation is a pivotal component of a variety of diseases, such as atherosclerosis and tumour progression. Various naturally occurring phytochemicals…”
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Decreased levels of alpha-1-acid glycoprotein are related to the mortality of septic patients in the emergency department by Barroso-Sousa, Romualdo, Lobo, Romulo R., Mendonça, Patricia R., Memória, Renan R., Spiller, Fernando, Cunha, Fernando Q., Pazin-Filho, Antonio

“…To determine the validity of alpha-1-acid glycoprotein as a novel biomarker for mortality in patients with severe sepsis. We prospectively included patients…”
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Possible mechanisms of neutrophil activation in Behçet's disease by Neves, Fabricio Souza, Spiller, Fernando

“…Behçet's disease (BD) is a systemic inflammatory disorder characterized by recurrent episodes of acute inflammation consisting mainly of neutrophil…”
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Divergent Role OF Heme Oxygenase Inhibition in the Pathogenesis of Sepsis by Freitas, Andressa, Alves-Filho, José C., Trevelin, Silvia Cellone, Spiller, Fernando, Suavinha, Marina Moreira, Nascimento, Daniele Carvalho, Pestana, Cezar Rangel, Dal-Secco, Daniela, Sônego, Fabiane, Czaikoski, Paula Giselle, Curti, Carlos, Barja-Fidalgo, Christina, Cunha, Fernando Q.

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Neutrophil paralysis in sepsis by Alves-Filho, José C, Spiller, Fernando, Cunha, Fernando Q

“…Sepsis develops when the initial host response is unable to contain the primary infection, resulting in widespread inflammation and multiple organ dysfunction…”
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Cannabinoid CB2 receptor agonist reduces local and systemic inflammation associated with pneumonia-induced sepsis in mice by Souza, Camila Fernandes, Borges, Luana Bolsoni, Oliveira, Filipe Rodolfo Moreira Borges, Silva, Priscila Creppas de Souza, Patricio, Daniel Oliveira, Rosales, Thiele Osvaldt, Souza, Nicoly Fernandes, Spiller, Fernando, Mansur, Daniel Santos, Assreuy, Jamil, Sordi, Regina

“…Sepsis is a severe condition secondary to dysregulated host response to infection leading to tissue damage and organ dysfunction. Cannabinoid CB2 receptor has…”
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Enterococcus faecalis: implications for host health by Boeder, Ariela Maína, Spiller, Fernando, Carlstrom, Mattias, Izídio, Geison Souza

“…The microbiota represents a crucial area of research in maintaining human health due to its potential for uncovering novel biomarkers, therapies, and molecular…”
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Chitosan/genipin modified electrode for voltammetric determination of interleukin-6 as a biomarker of sepsis by de Matos Morawski, Franciele, Dias, Greicy Brisa Malaquias, Sousa, Kelline Alaide Pereira, Formiga, Rodrigo, Spiller, Fernando, Parize, Alexandre Luis, Báfica, André, Jost, Cristiane Luisa

“…Ultrasensitive electroanalytical monitoring of interleukin-6 levels in serum samples has emerged as a valuable tool for the early diagnosis of inflammatory…”
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Antioxidants Improve Oxaliplatin-Induced Peripheral Neuropathy in Tumor-Bearing Mice Model: Role of Spinal Cord Oxidative Stress and Inflammation by Agnes, Jonathan Paulo, Santos, Vitória Wibbelt Dos, das Neves, Raquel Nascimento, Gonçalves, Rosângela Mayer, Delgobo, Marina, Girardi, Carolina Saibro, Lückemeyer, Débora Denardin, Ferreira, Marcella de Amorim, Macedo-Júnior, Sérgio José, Lopes, Samantha Cristiane, Spiller, Fernando, Gelain, Daniel Pens, Moreira, José Cláudio Fonseca, Prediger, Rui Daniel, Ferreira, Juliano, Zanotto-Filho, Alfeu

“…Chemotherapy-Induced Peripheral Neuropathy (CIPN) is a common, difficult-to-treat, and dose-limiting side effect associated with Oxaliplatin (OXA) treatment…”
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WITHDRAWN: Neutrophil activation in Behçet's Disease by Neves, Fabricio Souza, Spiller, Fernando

“…The Publisher regrets that this article is an accidental duplication of an article that has already been published,…”
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Effect of p-cymene and rosmarinic acid on gastric ulcer healing – Involvement of multiple endogenous curative mechanisms by Formiga, Rodrigo de Oliveira, Alves Júnior, Edvaldo Balbino, Vasconcelos, Roseane Carvalho, Araújo, Aurigena Antunes, de Carvalho, Thaís Gomes, de Araújo Junior, Raimundo Fernandes, Guerra, Gerlane Bernardo Coelho, Vieira, Giciane Carvalho, de Oliveira, Kardilandia Mendes, Diniz, Margareth de Fátima Formiga Melo, Sobral, Marianna Vieira, Barbosa Filho, José Maria, Spiller, Fernando, Batista, Leônia Maria

“…•p-Cymene and rosmarinic acid pre-treatment prevent gastric and duodenal ulcers in animal models.•p-Cymene and rosmarinic acid display gastric ulcer healing…”
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