Search Results - "SPERK, G"

Patterns of mRNA and protein expression for 12 GABAA receptor subunits in the mouse brain by Hörtnagl, H, Tasan, R.O, Wieselthaler, A, Kirchmair, E, Sieghart, W, Sperk, G

“…Graphical abstract Highlights ► The distribution of GABAA receptor subunits is highly heterogeneous. ► The distribution of mRNAs corresponds to that of…”
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Subunit composition, distribution and function of GABA(A) receptor subtypes by Sieghart, W, Sperk, G

“…GABA(A) receptors are the major inhibitory neurotransmitter receptors in the brain and are the site of action of many clinically important drugs. These…”
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NPY controls fear conditioning and fear extinction by combined action on Y 1 and Y 2 receptors by Verma, D, Tasan, RO, Herzog, H, Sperk, G

“…BACKGROUND AND PURPOSE Neuropeptide Y (NPY) and its receptors have been implicated in the control of emotional‐affective processing, but the mechanism is…”
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GABA A receptors: immunocytochemical distribution of 13 subunits in the adult rat brain by Pirker, S, Schwarzer, C, Wieselthaler, A, Sieghart, W, Sperk, G

“…GABA A receptors are ligand-operated chloride channels assembled from five subunits in a heteropentameric manner. Using immunocytochemistry, we investigated…”
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The role of Neuropeptide Y in fear conditioning and extinction by Tasan, R.O, Verma, D, Wood, J, Lach, G, Hörmer, B, de Lima, T.C.M, Herzog, H, Sperk, G

“…Abstract While anxiety disorders are the brain disorders with the highest prevalence and constitute a major burden for society, a considerable number of…”
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Structure and function of the amygdaloid NPY system: NPY Y2 receptors regulate excitatory and inhibitory synaptic transmission in the centromedial amygdala by Wood, J., Verma, D., Lach, G., Bonaventure, P., Herzog, H., Sperk, G., Tasan, R. O.

“…The amygdala is essential for generating emotional-affective behaviors. It consists of several nuclei with highly selective, elaborate functions. In…”
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Progressive loss of phasic, but not tonic, GABAA receptor-mediated inhibition in dentate granule cells in a model of post-traumatic epilepsy in rats by Pavlov, I, Huusko, N, Drexel, M, Kirchmair, E, Sperk, G, Pitkänen, A, Walker, M.C

“…Abstract Traumatic brain injury (TBI) is a risk factor for the development of epilepsy, which can occur months to years after the insult. The hippocampus is…”
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NPY controls fear conditioning and fear extinction by combined action on Y1 and Y2 receptors by Verma, D, Tasan, RO, Herzog, H, Sperk, G

“…BACKGROUND AND PURPOSE Neuropeptide Y (NPY) and its receptors have been implicated in the control of emotional‐affective processing, but the mechanism is…”
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Parvalbumin interneurons and calretinin fibers arising from the thalamic nucleus reuniens degenerate in the subiculum after kainic acid-induced seizures by Drexel, M, Preidt, A.P, Kirchmair, E, Sperk, G

“…Abstract The subiculum is the major output area of the hippocampus. It is closely interconnected with the entorhinal cortex and other parahippocampal areas. In…”
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Increased novelty-induced motor activity and reduced depression-like behavior in neuropeptide Y (NPY)–Y4 receptor knockout mice by Tasan, R.O, Lin, S, Hetzenauer, A, Singewald, N, Herzog, H, Sperk, G

“…Abstract There is growing evidence that neuropeptide Y (NPY) acting through Y1 and Y2 receptors has a prominent role in modulating anxiety- and depression-like…”
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Pancreatic polypeptide and its central Y 4 receptors are essential for cued fear extinction and permanent suppression of fear by Verma, D, Hörmer, B, Bellmann‐Sickert, K, Thieme, V, Beck‐Sickinger, A G, Herzog, H, Sperk, G, Tasan, R O

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Altered GABA transmission in a mouse model of increased trait anxiety by Tasan, R.O, Bukovac, A, Peterschmitt, Y.N, Sartori, S.B, Landgraf, R, Singewald, N, Sperk, G

“…Abstract Anxiety disorders are the most prevalent central nervous system diseases imposing a high social burden to our society. Emotional processing is…”
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NPY Y2 receptors in the central amygdala reduce cued but not contextual fear by Verma, D., Wood, J., Lach, G., Mietzsch, M., Weger, S., Heilbronn, R., Herzog, H., Bonaventure, P., Sperk, G., Tasan, R.O.

“…The amygdala is fundamental for associative fear and extinction learning. Recently, also the central nucleus of the amygdala (CEA) has emerged as a site of…”
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Pancreatic polypeptide and its central Y4 receptors are essential for cued fear extinction and permanent suppression of fear by Verma, D, Hörmer, B, Bellmann‐Sickert, K, Thieme, V, Beck‐Sickinger, A G, Herzog, H, Sperk, G, Tasan, R O

“…Background and purpose Avoiding danger and finding food are closely related behaviours that are essential for surviving in a natural environment. Growing…”
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Powerful Anticonvulsant Action of IL-1 Receptor Antagonist on Intracerebral Injection and Astrocytic Overexpression in Mice by Vezzani, A., Moneta, D., Conti, M., Richichi, C., Ravizza, T., De Luigi, A., De Simoni, M. G., Sperk, G., Andell-Jonsson, S., Lundkvist, J., Iverfeldt, K., Bartfai, T.

“…IL-1β and its endogenous receptor antagonist (IL-1Ra) are rapidly induced by seizures in the rodent hippocampus. Exogenously applied IL-1β prolongs seizures in…”
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Neuropeptide Y-Y2 receptor knockout mice: influence of genetic background on anxiety-related behaviors by Zambello, E, Zanetti, L, Hédou, G.F, Angelici, O, Arban, R, Tasan, R.O, Sperk, G, Caberlotto, L

“…Abstract Neuropeptide Y (NPY) has been extensively studied in relation to anxiety and depression but of the seven NPY receptors known to date, it is not yet…”
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Anticonvulsant effects and behavioural outcomes of rAAV serotype 1 vector-mediated neuropeptide Y overexpression in rat hippocampus by Noe, F, Vaghi, V, Balducci, C, Fitzsimons, H, Bland, R, Zardoni, D, Sperk, G, Carli, M, During, M J, Vezzani, A

“…Neuropeptide Y (NPY) is an endogenous peptide with powerful anticonvulsant properties. Its overexpression in the rat hippocampus, mediated by the local…”
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Altered expression of GABAA and GABAB receptor subunit mRNAs in the hippocampus after kindling and electrically induced status epilepticus by NISHIMURA, T, SCHWARZER, C, GASSER, E, KATO, N, VEZZANI, A, SPERK, G

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GABA A receptor subunits in the rat hippocampus I: Immunocytochemical distribution of 13 subunits by Sperk, G, Schwarzer, C, Tsunashima, K, Fuchs, K, Sieghart, W

“…The GABA A receptor is a ligand-operated chloride channel. It has a pentameric structure. In mammalian brain different subunits are recruited from four gene…”
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Delayed stress-induced differences in locomotor and depression-related behaviour in female neuropeptide-Y Y1 receptor knockout mice by Painsipp, E., Sperk, G., Herzog, H., Holzer, P.

“…Neuropeptide-Y acting through Y1 receptors reduces anxiety and stress sensitivity in rodents. In Y1 receptor knockout (Y1−/−) mice, however, anxiety-related…”
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