Search Results - "SPERELAKIS, N"

Effect of variation in membrane excitability on propagation velocity of simulated action potentials for cardiac muscle and smooth muscle in the electric field model for cell-to-cell transmission of excitation by Sperelakis, N., Kalloor, B.

“…We have previously published several studies on the propagation of simulated action potentials (APs) of cardiac muscle and smooth muscle using the PSpice…”
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Inwardly rectifying potassium current in rat fetal and neonatal ventricular cardiomyocytes by Masuda, H, Sperelakis, N

“…Whole cell and single-channel inwardly rectifying potassium currents (IK1) of freshly isolated single fetal (12 and 18 days) and neonatal (1, 5, and 10 days)…”
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Effect of external resistance on propagation of action potentials in cardiac muscle and visceral smooth muscle in PSpice simulation by Sperelakis, N., Murali, K.P.V.

“…Propagation of action potentials in cardiac muscle and visceral smooth muscle were simulated using the PSpice program. Excitation was transmitted from cell to…”
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cGMP Inhibits the Activity of Single Calcium Channels in Embryonic Chick Heart Cells by Tohse, Noritsugu, Sperelakis, Nicholas

“…Effects of cGMP on the slow (L-type) Ca channels of cultured chick embryonic cardiomyocytes were investigated by a cell-attached patch-clamp method…”
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Regulation of Ca2+ channel currents by intracellular ATP in smooth muscle cells of rat mesenteric artery by Yokoshiki, H, Katsube, Y, Sperelakis, N

“…Regulation of L-type Ca2+ channels of vascular smooth muscle (VSM) cells by adenosine 3',5'-cyclic monophosphate (cAMP)-dependent and guanosine 3',5'-cyclic…”
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Involvement of a GTP-Binding Protein in Stimulating Action of Angiotensin II on Calcium Channels in Vascular Smooth Muscle Cells by Ohya, Yusuke, Sperelakis, Nicholas

“…The possible involvement of a GTP-binding protein in the regulation of Ca channels by angiotensin II (Ang II) in vascular muscle cells was investigated by the…”
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An Electric Field Mechanism for Transmission of Excitation Between Myocardial Cells by Sperelakis, Nicholas

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Regulation of calcium slow channels of cardiac muscle by cyclic nucleotides and phosphorylation by Sperelakis, N

“…The voltage- and time-dependent slow channels in the myocardial cell membrane are the major pathway by which Ca2+ ions enter the cell during excitation for…”
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ATP Regulation of the Slow Calcium Channels in Vascular Smooth Muscle Cells of Guinea Pig Mesenteric Artery by Ohya, Yusuke, Sperelakis, Nicholas

“…Effects of intracellularly perfused ATP, and extracellularly applied cyanide and 2-deoxy-D-glucose, on fast and slow Ca channel currents of isolated single…”
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Effects of diacetyl monoxime on cardiac excitation-contraction coupling by Li, T, Sperelakis, N, Teneick, R E, Solaro, R J

“…Diacetyl monoxime (DAM) is a negative inotropic agent. To identify the mechanism of its actions, electrical and mechanical studies with various cardiac tissues…”
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Novel isoform of Ca2+ channel in rat fetal cardiomyocytes by Tohse, N, Masuda, H, Sperelakis, N

“…1. Single cardiomyocytes of 18-day-old rat fetuses were isolated to characterize the cardiac Ca2+ channels in the fetal period, using whole-cell voltage clamp…”
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Tocolytic agents act on calcium channel current in single smooth muscle cells of pregnant rat uterus by Ohya, Y, Sperelakis, N

“…Effects of Ca2+ channel blockers and clinically important tocolytic agents, Mg2+ and beta-agonists, were examined on the Ca2+ channel current recorded from…”
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Ca2+ currents in human colonic smooth muscle cells by Xiong, Z, Sperelakis, N, Noffsinger, A, Fenoglio-Preiser, C

“…Voltage-gated Ca2+ currents were investigated in single smooth muscle cells freshly isolated from the circular layer of the human colon (ascending and…”
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Fast sodium currents induced by serum in human uterine leiomyosarcoma cells by Kusaka, M, Sperelakis, N

“…We previously demonstrated that fast Na+ channels are expressed in uterine smooth muscle cells during pregnancy [Y. Ohya, and N. Sperelakis. Am. J. Physiol…”
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Regulation of the slow Ca++ channels of myocardial cells by Sperelakis, N, Katsube, Y, Yokoshiki, H, Sada, H, Sumii, K

“…Contraction of the heart is regulated by a number of mechanisms, such as neurotransmitters, hormones, autacoids, pH, intracellular ATP, and Ca++ ions. These…”
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Bupivacaine and lidocaine blockade of calcium-mediated slow action potentials in guinea pig ventricular muscle by Coyle, D E, Sperelakis, N

“…The effects of bupivacaine and lidocaine on the slow-rising action potentials, induced by superfusion with high-K+ (26 mM) Tyrode's solution with 10(-6) M…”
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Regulation of calcium channel current in A7r5 vascular smooth muscle cells by cyclic nucleotides by Lorenz, J N, Bielefeld, D R, Sperelakis, N

“…In vascular smooth muscle (VSM) cells, the slow inward calcium current (ICa) may be regulated by phosphorylation of the calcium channel protein or of…”
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Changes in calcium channel current densities in rat colonic smooth muscle cells during development and aging by Xiong, Z, Sperelakis, N, Noffsinger, A, Fenoglio-Preiser, C

“…The age-related changes of Ca2+ channel currents were investigated in freshly isolated single smooth muscle cells from the circular layer of the distal colon…”
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Amino acid substitutions in the rat Na+, K(+)-ATPase alpha 2-subunit alter the cation regulation of pump current expressed in HeLa cells by Yamamoto, S, Kuntzweiler, T A, Wallick, E T, Sperelakis, N, Yatani, A

“…1. To study the functional role of negatively charged amino acids (E327 and D925) located in the transmembrane region of the rat alpha 2-isoform of the Na+,…”
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Regulation of ion channels in myocardial cells and protection of ischemic myocardium by SPERELAKIS, N, SUNAGAWA, M, YOKOSHIKI, H, SEKI, T, NAKAMURA, M

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