Search Results - "SPENCER, Charles"

Territorial expansion and primary state formation by Spencer, Charles S

“…A major research problem in anthropology is the origin of the state and its bureaucratic form of governance. Of particular importance for evaluating theories…”
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Personalized Proteomics: The Future of Precision Medicine by Duarte, Trevor T, Spencer, Charles T

“…Medical diagnostics and treatment has advanced from a one size fits all science to treatment of the patient as a unique individual. Currently, this is limited…”
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Biologics in refractory idiopathic inflammatory myositis (IIM): What experience in juvenile vs adult myositis tells us about the use of biologics in pediatric IIM by Patwardhan, Anjali, Spencer, Charles H.

“…Juvenile dermatomyositis (JDM) is an extremely heterogeneous orphan disease with limited amount of dedicated research on the subject matter. Recent research…”
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Engineered Extracellular Vesicles Derived from Dermal Fibroblasts Attenuate Inflammation in a Murine Model of Acute Lung Injury by Salazar‐Puerta, Ana I., Rincon‐Benavides, María A., Cuellar‐Gaviria, Tatiana Z., Aldana, Julian, Vasquez Martinez, Gabriela, Ortega‐Pineda, Lilibeth, Das, Devleena, Dodd, Daniel, Spencer, Charles A., Deng, Binbin, McComb, David W., Englert, Joshua A., Ghadiali, Samir, Zepeda‐Orozco, Diana, Wold, Loren E., Gallego‐Perez, Daniel, Higuita‐Castro, Natalia

“…Acute respiratory distress syndrome (ARDS) represents a significant burden to the healthcare system, with ≈200 000 cases diagnosed annually in the USA. ARDS…”
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Histone lactylation-regulated METTL3 promotes ferroptosis via m6A-modification on ACSL4 in sepsis-associated lung injury by Wu, Dan, Spencer, Charles B., Ortoga, Lilibeth, Zhang, Hao, Miao, Changhong

“…Elevated lactate levels are a significant biomarker of sepsis and are positively associated with sepsis-related mortality. Sepsis-associated lung injury (ALI)…”
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Early Components of the Complement Classical Activation Pathway in Human Systemic Autoimmune Diseases by Lintner, Katherine E, Wu, Yee Ling, Yang, Yan, Spencer, Charles H, Hauptmann, Georges, Hebert, Lee A, Atkinson, John P, Yu, C Yung

“…The complement system consists of effector proteins, regulators, and receptors that participate in host defense against pathogens. Activation of the complement…”
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Alginate Hydrogels with Embedded ZnO Nanoparticles for Wound Healing Therapy by Cleetus, Carol M, Alvarez Primo, Fabian, Fregoso, Gisel, Lalitha Raveendran, Nivedita, Noveron, Juan C, Spencer, Charles T, Ramana, Chinatalapalle V, Joddar, Binata

“…In this in-vitro study, we designed a 3D printed composite of zinc oxide (ZnO) nanoparticles (NPs) with photocatalytic activities encapsulated within hydrogel…”
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An unprecedented COPA gene mutation in two patients in the same family: comparative clinical analysis of newly reported patients with other known COPA gene mutations by Patwardhan, Anjali, Spencer, Charles H

“…The COPA syndrome is a newly recognized monogenic, autosomal dominant autoimmune disease presenting mostly presenting in childhood. Clinical features include…”
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Mammalian Target of Rapamycin Protein Complex 2 Regulates Differentiation of Th1 and Th2 Cell Subsets via Distinct Signaling Pathways by Lee, Keunwook, Gudapati, Prathyusha, Dragovic, Srdjan, Spencer, Charles, Joyce, Sebastian, Killeen, Nigel, Magnuson, Mark A., Boothby, Mark

“…Many functions of the mammalian target of rapamycin (mTOR) complex 1 (mTORC1) have been defined, but relatively little is known about the biology of an…”
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The association of allostasis with alcohol use: A case–control study in males with and without alcohol use disorder by Portillo, Carlos, Adinoff, Bryon, Spencer, Charles T., Field, Craig A.

“…Allostatic load (AL) is associated with a heightened predisposition to disease due to prolonged activation of biological stress-response systems. Alcohol use…”
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Live and Inactivated Influenza Vaccines Induce Similar Humoral Responses, but Only Live Vaccines Induce Diverse T-Cell Responses in Young Children by Hoft, Daniel F., Babusis, Elizabeth, Worku, Shewangizaw, Spencer, Charles T., Lottenbach, Kathleen, Truscott, Steven M., Abate, Getahun, Sakala, Isaac G., Edwards, Kathryn M., Creech, Buddy, Gerber, Michael A., Bernstein, David I., Newman, Frances, Graham, Irene, Anderson, Edwin L., Belshe, Robert B.

“…Background. Two doses of either trivalent live attenuated or inactivated influenza vaccines (LAIV and TIV, respectively) are approved for young children (>24…”
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Time for change at PROJ in 2021 by Spencer, Charles H, Martini, Alberto

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IL-15 regulates homeostasis and terminal maturation of NKT cells by Gordy, Laura E, Bezbradica, Jelena S, Flyak, Andrew I, Spencer, Charles T, Dunkle, Alexis, Sun, Jingchun, Stanic, Aleksandar K, Boothby, Mark R, He, You-Wen, Zhao, Zhongming, Van Kaer, Luc, Joyce, Sebastian

“…Semi-invariant NKT cells are thymus-derived innate-like lymphocytes that modulate microbial and tumor immunity as well as autoimmune diseases. These…”
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Ancient palace complex (300–100 BC) discovered in the Valley of Oaxaca, Mexico by Redmond, Elsa M., Spencer, Charles S.

“…Recently completed excavations at the site of El Palenque in Mexico’s Valley of Oaxaca have recovered the well-preserved remains of a palace complex dated by…”
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Age and fecal microbial strain-specific differences in patients with spondyloarthritis by Stoll, Matthew L, Weiss, Pamela F, Weiss, Jennifer E, Nigrovic, Peter A, Edelheit, Barbara S, Bridges, Jr, S Lou, Danila, Maria I, Spencer, Charles H, Punaro, Marilynn G, Schikler, Kenneth, Reiff, Andreas, Kumar, Ranjit, Cron, Randy Q, Morrow, Casey D, Lefkowitz, Elliot J

“…Prior studies have demonstrated abnormalities in the composition of the gastrointestinal microbiota in pediatric and adult patients with spondyloarthritis…”
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Biologics in refractory myositis: experience in juvenile vs. adult myositis; part II: emerging biologic and other therapies on the horizon by Patwardhan, Anjali, Spencer, Charles H

“…The idiopathic inflammatory myopathies (IIM) until recently have been considered a heterogeneous broad group of six autoimmune muscle diseases. Initially,…”
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METTL3‐mediated N6‐methyladenosine exacerbates ferroptosis via m6A‐IGF2BP2‐dependent mitochondrial metabolic reprogramming in sepsis‐induced acute lung injury by Zhang, Hao, Wu, Dan, Wang, Yanghanzhao, Guo, Kefang, Spencer, Charles B., Ortoga, Lilibeth, Qu, Mengdi, Shi, Yuxin, Shao, Yuwen, Wang, Zhiping, Cata, Juan P., Miao, Changhong

“…Abstract Neutrophil extracellular traps (NETs), released by polymorphonuclear neutrophils (PMNs), exert a robust antimicrobial function in infectious diseases…”
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Obesity Exacerbates the Cytokine Storm Elicited by Francisella tularensis Infection of Females and Is Associated with Increased Mortality by Spencer, Charles, Garza, Kristine M., Saenz Portillo, Pamela, Sanchez, Michelle A., Setzu, Nicole, Palfreeman, Matthew, Ramos Muniz, Mireya G., Gosselink, Kristin L.

“…Infection with Francisella tularensis, the causative agent of the human disease tularemia, results in the overproduction of inflammatory cytokines, termed the…”
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Ferritin-mediated neutrophil extracellular traps formation and cytokine storm via macrophage scavenger receptor in sepsis-associated lung injury by Zhang, Hao, Wu, Dan, Wang, Yanghanzhao, Shi, Yuxin, Shao, Yuwen, Zeng, Fu, Spencer, Charles B, Ortoga, Lilibeth, Wu, Dehua, Miao, Changhong

“…Sepsis is a severe systemic inflammatory disorder manifested by a dysregulated immune response to infection and multi-organ failure. Numerous studies have…”
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Manipulation of the spin helix in FeGe thin films and FeGe/Fe multilayers by Porter, Nicholas A., Spencer, Charles S., Temple, Rowan C., Kinane, Christian J., Charlton, Timothy R., Langridge, Sean, Marrows, Christopher H.

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