Search Results - "SPENCE, A. M"
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1
Biogeochemical controls on ammonium accumulation in the surface layer of the Southern Ocean
Published in Biogeosciences (07-02-2022)“…The production and removal of ammonium (NH4+) are essential upper-ocean nitrogen cycle pathways, yet in the Southern Ocean where NH4+ has been observed to…”
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Summertime productivity and carbon export potential in the Weddell Sea, with a focus on the waters adjacent to Larsen C Ice Shelf
Published in Biogeosciences (24-11-2021)“…The Weddell Sea represents a point of origin in the Southern Ocean where globally important water masses form. Biological activities in Weddell Sea surface…”
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3
Predicting the efficacy of radiotherapy in individual glioblastoma patients in vivo: a mathematical modeling approach
Published in Physics in medicine & biology (21-06-2010)“…Glioblastoma multiforme (GBM) is the most malignant form of primary brain tumors known as gliomas. They proliferate and invade extensively and yield short life…”
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4
The Genetic Architecture of Selection at the Human Dopamine Receptor D4 ( DRD4) Gene Locus
Published in American journal of human genetics (01-05-2004)“…Associations of the seven-repeat (7R) allele of the human dopamine receptor D4 ( DRD4) gene with both the personality trait of novelty seeking and attention…”
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5
Autism and the serotonin transporter: the long and short of it
Published in Molecular psychiatry (01-12-2005)“…Autism is a neurodevelopmental disorder manifesting early in childhood. Some symptoms of autism are alleviated by treatment with selective serotonin reuptake…”
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6
A seasonal analysis of aerosol NO3- sources and NOx oxidation pathways in the Southern Ocean marine boundary layer
Published in Atmospheric chemistry and physics (22-05-2023)“…Nitrogen oxides, collectively referred to as NOx (NO + NO2), are an important component of atmospheric chemistry involved in the production and destruction of…”
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The importance of alkyl nitrates and sea ice emissions to atmospheric NOx sources and cycling in the summertime Southern Ocean marine boundary layer
Published in Atmospheric chemistry and physics (21-01-2022)“…Atmospheric nitrate originates from the oxidation of nitrogen oxides (NOx=NO+NO2) and impacts both tropospheric chemistry and climate. NOx sources, cycling and…”
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8
Evidence for multiple loci from a genome scan of autism kindreds
Published in Molecular psychiatry (01-11-2006)“…We performed a genome-wide linkage scan using highly polymorphic microsatellite markers. To minimize genetic heterogeneity, we focused on sibpairs meeting the…”
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High prevalence of rare dopamine receptor D4 alleles in children diagnosed with attention-deficit hyperactivity disorder
Published in Molecular psychiatry (01-05-2003)“…Associations have been reported of the 7-repeat (7R) allele of the human dopamine receptor D4 (DRD4) gene with both the personality trait of novelty seeking…”
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10
Mortality, hepatopathy and liver copper concentrations in artificially reared Jersey calves before and after reductions in copper supplementation
Published in Veterinary record (12-01-2013)“…High winter mortality (28 per cent) in female Jersey calves (<one month) characterised by mild hepatopathy and enteropathy was investigated. Liver copper (Cu)…”
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Dopamine genes and ADHD
Published in Neuroscience and biobehavioral reviews (2000)“…Family, twin, and adoption studies have documented a strong genetic basis for ADHD/HKD, but these studies do not identify specific genes linked to the…”
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Journal Article Conference Proceeding -
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Kinetic Quantitation of Cerebral PET-FDG Studies Without Concurrent Blood Sampling: Statistical Recovery of the Arterial Input Function
Published in IEEE transactions on medical imaging (01-03-2010)“…Kinetic quantitation of dynamic positron emission tomography (PET) studies via compartmental modeling usually requires the time-course of the radio-tracer…”
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13
An approach for assessing and ranking fisheries management scenarios in spatially delimited marine areas
Published in ICES journal of marine science (29-06-2023)“…Abstract Spatial restrictions to human activities such as bottom trawling are increasingly used to improve the ecological condition of disturbed habitats. Such…”
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14
Negative regulation of male development in Caenorhabditis elegans by a protein-protein interaction between TRA-2A and FEM-3
Published in Genes & development (01-06-1999)“…The tra-2 gene of the nematode Caenorhabditis elegans encodes a predicted membrane protein, TRA-2A, that promotes XX hermaphrodite development. Genetic…”
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15
Imaging and Nanomedicine for Diagnosis and Therapy in the Central Nervous System: Report of the Eleventh Annual Blood-Brain Barrier Disruption Consortium Meeting
Published in AJNR. American journal of neuroradiology (01-03-2006)“…The blood-brain barrier (BBB) presents a major obstacle to the treatment of malignant brain tumors and other central nervous system (CNS) diseases. The…”
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Journal Article Conference Proceeding -
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Phase I study of paclitaxel in patients with recurrent malignant glioma: a North American Brain Tumor Consortium report
Published in Journal of clinical oncology (01-06-1998)“…To determine the maximum-tolerated dose (MTD) of paclitaxel administered as a 3-hour infusion in patients with recurrent malignant glioma. Patients were…”
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Sequence variants of the DRD4 gene in autism: Further evidence that rare DRD4 7R haplotypes are ADHD specific
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (05-07-2005)“…A high prevalence of rare dopamine receptor D4 (DRD4) alleles in children diagnosed with attention‐deficit hyperactivity disorder (ADHD) has been reported…”
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Phase II study of paclitaxel in patients with recurrent malignant glioma
Published in Journal of clinical oncology (01-08-1996)“…To assess the efficacy and toxicity of paclitaxel administered as a 3-hour infusion to patients with recurrent malignant glioma. Adult patients with recurrent…”
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A preliminary investigation into the apparent abhesive effect of stearic acid on cured silicone elastomer
Published in International journal of adhesion and adhesives (01-12-2010)“…The effect of addition of small amounts of stearic acid on the adhesive properties of polydimethylsiloxane (PDMS) was investigated. Stearic acid reduced the…”
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Loss of information due to ambiguous haplotyping of SNPs
Published in Nature genetics (01-04-1999)“…A string of tightly linked diallelic loci A (SNPs), with number of loci equal to k, might appear equivalent to a single locus with 2 super(k) alleles, because…”
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