Search Results - "SPEARS, Glen W."
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Synthesis and antinephritic activities of quinoline-3-carboxamides and related compounds
Published in Bioorganic & medicinal chemistry letters (07-01-2002)“…A series of linomide-related quinoline-3-carboxamides and their analogues was prepared and evaluated for antinephritic activities. The 6-MeS derivative 7a was…”
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Quinoline-3-carbothioamides and related compounds as novel immunomodulating agents
Published in Bioorganic & medicinal chemistry letters (02-09-2002)“…A series of quinoline-3-carbothioamides and their analogues was prepared via four synthetic routes and evaluated for their antinephritic and immunomodulating…”
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An efficient synthesis of a class of novel N-Alkyl-N-aryl-4-hydroxy-1-methyl-2-oxo-1,2-dihydro-3-quinolinecarbothioamides
Published in Journal of heterocyclic chemistry (01-07-2002)“…The novel title compounds have been prepared in high yield by an optimized amide coupling followed by a Dieckmann cyclization. Additionally, this new route is…”
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Studies on Anti-inflammatory Agents. V. Synthesis and Pharmacological Properties of 3-(Difluoromethyl)-1-(4-methoxyphenyl)-5-[4-(methylsulfinyl)phenyl]pyrazole and Related Compounds
Published in Chemical & pharmaceutical bulletin (01-09-1997)“…A series of novel 1, 5-diphenylpyrazole derivatives bearing hydrophilic substituents was prepared. The anti-inflammatory and analgesic activities of these…”
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Enolate equilibria and force field parameters
Published in Journal of organic chemistry (01-04-1987)Get full text
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The First Synthesis of N-Alkyl-N-Arylthiocarbamoylacetates and Acetic Acids
Published in Synthetic communications (01-02-2000)“…N-Alkyl-N-arylthiocarbamoylacetates, the key intermediates for the synthesis of novel antinephritic agents, have been prepared for the first time. Some of the…”
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