Search Results - "SOUZA, Danielle G"
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Therapeutic treatment of Zika virus infection using a brain-penetrating antiviral peptide
Published in Nature materials (01-11-2018)“…Zika virus is a mosquito-borne virus that is associated with neurodegenerative diseases, including Guillain–Barré syndrome 1 and congenital Zika syndrome 2 …”
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Tissue Dependent Role of PTX3 During Ischemia-Reperfusion Injury
Published in Frontiers in immunology (10-07-2019)“…Reperfusion of an ischemic tissue is the treatment of choice for several diseases, including myocardial infarction and stroke. However, reperfusion of an…”
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3
Transient TLR activation restores inflammatory response and ability to control pulmonary bacterial infection in germfree mice
Published in The Journal of immunology (1950) (01-02-2012)“…Mammals are colonized by an astronomical number of commensal microorganisms on their environmental exposed surfaces. These symbiotic species build up a complex…”
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Zika Virus Promotes Neuronal Cell Death in a Non-Cell Autonomous Manner by Triggering the Release of Neurotoxic Factors
Published in Frontiers in immunology (23-08-2017)“…Zika virus (ZIKV) has recently caused a worldwide outbreak of infections associated with severe neurological complications, including microcephaly in infants…”
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Animal model of arthritis and myositis induced by the Mayaro virus
Published in PLoS neglected tropical diseases (01-05-2019)“…The Mayaro virus (MAYV) is an endemic arbovirus in South American countries, where it is responsible for sporadic outbreaks of Mayaro fever. Clinical…”
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The Aryl Hydrocarbon Receptor Modulates Production of Cytokines and Reactive Oxygen Species and Development of Myocarditis during Trypanosoma cruzi Infection
Published in Infection and immunity (01-10-2016)“…The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor involved in controlling several aspects of immune responses, including the…”
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Essential Role of Platelet-Activating Factor Receptor in the Pathogenesis of Dengue Virus Infection
Published in Proceedings of the National Academy of Sciences - PNAS (18-08-2009)“…Severe dengue infection in humans causes a disease characterized by thrombocytopenia, increased levels of cytokines, increased vascular permeability,…”
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Contribution of macrophage migration inhibitory factor to the pathogenesis of dengue virus infection
Published in The FASEB journal (01-01-2010)“…Dengue fever is an emerging viral disease transmitted by arthropods to humans in tropical countries. Dengue hemorrhagic fever (DHF) is escalating in frequency…”
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Lack of platelet‐activating factor receptor protects mice against diet‐induced adipose inflammation and insulin‐resistance despite fat pad expansion
Published in Obesity (Silver Spring, Md.) (01-03-2014)“…Objective The role of platelet‐activating factor (PAF) on diet‐induced inflammatory and metabolic dysfunction is unknown. The effects of diet‐induced metabolic…”
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10
Role of the chemokine receptors CCR1, CCR2 and CCR4 in the pathogenesis of experimental dengue infection in mice
Published in PloS one (29-12-2010)“…Dengue virus (DENV), a mosquito-borne flavivirus, is a public health problem in many tropical countries. Recent clinical data have shown an association between…”
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The Required Role of Endogenously Produced Lipoxin A4 and Annexin-1 for the Production of IL-10 and Inflammatory Hyporesponsiveness in Mice
Published in The Journal of immunology (1950) (15-12-2007)“…The appropriate development of an inflammatory response is central for the ability of a host to deal with any infectious insult. However, excessive, misplaced,…”
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The Long Pentraxin PTX3 Is Crucial for Tissue Inflammation after Intestinal Ischemia and Reperfusion in Mice
Published in The American journal of pathology (01-04-2009)“…The pentraxin superfamily is a group of evolutionarily conserved proteins that play important roles in the immune system. The long pentraxin PTX3 protein was…”
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In Vitro TNF-α Inhibitory Activity of Brazilian Plants and Anti-Inflammatory Effect of Stryphnodendron adstringens in an Acute Arthritis Model
Published in Evidence-based complementary and alternative medicine (01-01-2016)“…Stryphnodendron species, popularly named “barbatimão,” are traditionally used in Brazil as anti-inflammatory agents. This study aimed to investigate the effect…”
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IFN-γ production depends on IL-12 and IL-18 combined action and mediates host resistance to dengue virus infection in a nitric oxide-dependent manner
Published in PLoS neglected tropical diseases (01-12-2011)“…Dengue is a mosquito-borne disease caused by one of four serotypes of Dengue virus (DENV-1-4). Severe dengue infection in humans is characterized by…”
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Host Immune Response to ZIKV in an Immunocompetent Embryonic Mouse Model of Intravaginal Infection
Published in Viruses (17-06-2019)“…Zika virus (ZIKV) only induces mild symptoms in adults; however, it can cause congenital Zika syndrome (CZS), including microcephaly. Most of the knowledge on…”
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Adapting to environmental stresses: the role of the microbiota in controlling innate immunity and behavioral responses
Published in Immunological reviews (01-01-2012)“…Mammals are subject to colonization by an astronomical number of mutualistic and commensal microorganisms on their environmental exposed surfaces. These…”
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Role of the aryl hydrocarbon receptor in the immune response profile and development of pathology during Plasmodium berghei Anka infection
Published in Infection and immunity (01-08-2014)“…Infection with Plasmodium falciparum may result in severe disease affecting various organs, including liver, spleen, and brain, resulting in high morbidity and…”
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The Essential Role of the Intestinal Microbiota in Facilitating Acute Inflammatory Responses
Published in The Journal of immunology (1950) (15-09-2004)“…The restoration of blood flow, i.e., reperfusion, is the treatment of choice to save viable tissue following acute ischemia of a vascular territory…”
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Annexin A1-FPR2/ALX Signaling Axis Regulates Acute Inflammation during Chikungunya Virus Infection
Published in Cells (Basel, Switzerland) (31-08-2022)“…Chikungunya (CHIKV) is an arthritogenic alphavirus that causes a self-limiting disease usually accompanied by joint pain and/or polyarthralgia with disabling…”
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A model of DENV-3 infection that recapitulates severe disease and highlights the importance of IFN-γ in host resistance to infection
Published in PLoS neglected tropical diseases (01-05-2012)“…There are few animal models of dengue infection, especially in immunocompetent mice. Here, we describe alterations found in adult immunocompetent mice…”
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