Search Results - "SOUSA, Joao C"

Chronic Stress Causes Frontostriatal Reorganization and Affects Decision-Making by Dias-Ferreira, Eduardo, Sousa, João C, Melo, Irene, Morgado, Pedro, Mesquita, Ana R, Cerqueira, João J, Costa, Rui M, Sousa, Nuno

“…The ability to shift between different behavioral strategies is necessary for appropriate decision-making. Here, we show that chronic stress biases…”
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The choroid plexus transcriptome reveals changes in type I and II interferon responses in a mouse model of Alzheimer’s disease by Mesquita, Sandro Dá, Ferreira, Ana C, Gao, Fuying, Coppola, Giovanni, Geschwind, Daniel H, Sousa, João C, Correia-Neves, Margarida, Sousa, Nuno, Palha, Joana A, Marques, Fernanda

“…Highlights • The choroid plexus suffers distinct alterations in aging and in Alzheimer’s disease. • The CP transcriptome reveals an early induction of type I…”
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Mesenchymal stem cells secretome as a modulator of the neurogenic niche: basic insights and therapeutic opportunities by Salgado, Antonio J, Sousa, Joao C, Costa, Bruno M, Pires, Ana O, Mateus-Pinheiro, António, Teixeira, F G, Pinto, Luisa, Sousa, Nuno

“…Neural stem cells (NSCs) and mesenchymal stem cells (MSCs) share few characteristics apart from self-renewal and multipotency. In fact, the neurogenic and…”
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Kinetic profile of the transcriptome changes induced in the choroid plexus by peripheral inflammation by Marques, Fernanda, Sousa, João Carlos, Coppola, Giovanni, Falcão, Ana Luisa Mendanha, Rodrigues, Ana João, Geschwind, Daniel H., Sousa, Nuno, Correia-Neves, M, Palha, Joana Almeida

“…The choroid plexus, being part of the blood-brain barriers and responsible for the production of cerebrospinal fluid, is ideally positioned to transmit signals…”
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Lipocalin-2 is involved in emotional behaviors and cognitive function by Ferreira, Ana C, Pinto, Vítor, Dá Mesquita, Sandro, Novais, Ashley, Sousa, João C, Correia-Neves, Margarida, Sousa, Nuno, Palha, Joana A, Marques, Fernanda

“…Lipocalin-2 (LCN2), an iron-related protein well described to participate in the innate immune response, has been shown to modulate spine morphology and to…”
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Distribution of micropollutants in estuarine and sea water along the Portuguese coast by Sousa, João C.G., Barbosa, Marta O., Ribeiro, Ana R.L., Ratola, Nuno, Pereira, Manuel F.R., Silva, Adrián M.T.

“…This work provides the first spatial distribution report of micropollutants (MPs) in the entire Portuguese coast, comprising the ocean shore (sea water, SW)…”
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A Novel Control Architecture Based on Behavior Trees for an Omni-Directional Mobile Robot by Bernardo, Rodrigo, Sousa, João M. C., Botto, Miguel Ayala, Gonçalves, Paulo J. S.

“…Robotic systems are increasingly present in dynamic environments. This paper proposes a hierarchical control structure wherein a behavior tree (BT) is used to…”
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Fuzzy Multi-Item Newsvendor Problem: An Application to Inventory Management by Sousa, João M. C., Luís, Rodrigo, Santos, Rui Mirra, Mendonça, Luís, Vieira, Susana M.

“…This paper proposes a novel approach to the fuzzy newsvendor problem for inventory management applications. The main contributions of the paper are the…”
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Intelligent Sensors for Real-Time Decision-Making by Coito, Tiago, Firme, Bernardo, Martins, Miguel S. E., Vieira, Susana M., Figueiredo, João, Sousa, João M. C.

“…The simultaneous integration of information from sensors with business data and how to acquire valuable information can be challenging. This paper proposes the…”
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Stress shifts the response of the bed nucleus of the stria terminalis to an anxiogenic mode by Ventura-Silva, Ana P., Pêgo, José M., Sousa, João C., Marques, Ana R., Rodrigues, Ana J., Marques, Fernanda, Cerqueira, João J., Almeida, Osborne F. X., Sousa, Nuno

“…The bed nucleus of the stria terminalis (BNST) is critically implicated in anxiety behavior and control of the hypothalamus–pituitary–adrenal axis. Having…”
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The choroid plexus response to a repeated peripheral inflammatory stimulus by Marques, Fernanda, Sousa, João C, Coppola, Giovanni, Geschwind, Daniel H, Sousa, Nuno, Palha, Joana A, Correia-Neves, Margarida

“…Chronic systemic inflammation triggers alterations in the central nervous system that may relate to the underlying inflammatory component reported in…”
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Pattern recognition of hematological profiles of tumors of the digestive tract: an exploratory study by Santos-Silva, Miguel A., Sousa, Nuno, Majar, Marina, Machado, Miguel, Reis, Joana, Sousa, Joao C.

“…AimsIn this study, we aimed to apply laboratory blood analysis to identify the hematological (based on hemoglobin concentration, erythrocytes, hematocrit, and…”
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Lipocalin 2 is a choroid plexus acute-phase protein by Marques, Fernanda, Rodrigues, Ana João, Sousa, João Carlos, Coppola, Giovanni, Geschwind, Daniel H., Sousa, Nuno, Correia-Neves, M, Palha, Joana Almeida

“…Lipocalin 2 (LCN2) is able to sequester iron-loaded bacterial siderophores and, therefore, is known to participate in the mammalian innate immune response. Of…”
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Digital Twin of a Flexible Manufacturing System for Solutions Preparation by Coito, Tiago, Faria, Paulo, Martins, Miguel S. E., Firme, Bernardo, Vieira, Susana M., Figueiredo, João, Sousa, João M. C.

“…In the last few decades, there has been a growing necessity for systems that handle market changes and personalized customer needs with near mass production…”
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Characterization of antibiotic resistant enterococci isolated from untreated waters for human consumption in Portugal by Macedo, Ana S., Freitas, Ana R., Abreu, Cristina, Machado, Elisabete, Peixe, Luísa, Sousa, João C., Novais, Carla

“…Untreated drinking water is frequently overlooked as a source of antibiotic resistance in developed countries. To gain further insight on this topic, we…”
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Modulation of iron metabolism in aging and in Alzheimer's disease: relevance of the choroid plexus by Mesquita, Sandro D, Ferreira, Ana C, Sousa, João C, Santos, Nadine C, Correia-Neves, Margarida, Sousa, Nuno, Palha, Joana A, Marques, Fernanda

“…Iron is essential for mammalian cellular homeostasis. However, in excess, it promotes free radical formation and is associated with aging-related progressive…”
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Monitoring of the 17 EU Watch List contaminants of emerging concern in the Ave and the Sousa Rivers by Sousa, João C.G., Ribeiro, Ana R., Barbosa, Marta O., Ribeiro, Cláudia, Tiritan, Maria E., Pereira, M. Fernando R., Silva, Adrián M.T.

“…The occurrence of micropollutants in the environment is a matter of high concern. Some regulations have been published in the last years and a Watch List of…”
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Missing data in medical databases: Impute, delete or classify? by Cismondi, Federico, Fialho, André S, Vieira, Susana M, Reti, Shane R, Sousa, João M.C, Finkelstein, Stan N

“…Abstract Background The multiplicity of information sources for data acquisition in modern intensive care units (ICUs) makes the resulting databases…”
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Computational intelligence applied to discriminate bee pollen quality and botanical origin by Gonçalves, Paulo J.S., Estevinho, Letícia M., Pereira, Ana Paula, Sousa, João M.C., Anjos, Ofélia

“…•Application of computational intelligence models towards bee pollen characterization.•Predict physico-chemical composition of bee pollen mixture given their…”
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From the periphery to the brain: Lipocalin-2, a friend or foe? by Ferreira, Ana C, Dá Mesquita, Sandro, Sousa, João C, Correia-Neves, Margarida, Sousa, Nuno, Palha, Joana A, Marques, Fernanda

“…Lipocalin-2 (LCN2) is an acute-phase protein that, by binding to iron-loaded siderophores, acts as a potent bacteriostatic agent in the iron-depletion strategy…”
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