Search Results - "SOULE, BENJAMIN P."

Ionizing radiation-induced oxidative stress alters miRNA expression by Simone, Nicole L, Soule, Benjamin P, Ly, David, Saleh, Anthony D, Savage, Jason E, Degraff, William, Cook, John, Harris, Curtis C, Gius, David, Mitchell, James B

“…MicroRNAs (miRNAs) are small, highly conserved, non-coding RNA that alter protein expression and regulate multiple intracellular processes, including those…”
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Cellular stress induced alterations in microRNA let-7a and let-7b expression are dependent on p53 by Saleh, Anthony D, Savage, Jason E, Cao, Liu, Soule, Benjamin P, Ly, David, DeGraff, William, Harris, Curtis C, Mitchell, James B, Simone, Nicole L

“…Genotoxic stressors, such as radiation, induce cellular damage that activates pre-programmed repair pathways, some of which involve microRNAs (miRNA) that…”
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Therapeutic and clinical applications of nitroxide compounds by Soule, Benjamin P, Hyodo, Fuminori, Matsumoto, Ken-Ichiro, Simone, Nicole L, Cook, John A, Krishna, Murali C, Mitchell, James B

“…Nitroxide compounds have been used for many years as biophysical tools, but only during the past 15-20 years have the many interesting biochemical interactions…”
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Study design and baseline profile for adults with type 2 diabetes in the once-weekly subcutaneous SEmaglutide randomized PRAgmatic (SEPRA) trial by Buse, John B, Nordahl Christensen, Helene, Harty, Brian J, Mitchell, Julie, Soule, Benjamin P, Zacherle, Emily, Cziraky, Mark, Willey, Vincent J

“…IntroductionOnce-weekly subcutaneous semaglutide, a glucagon-like peptide-1 analog, is approved in the USA as an adjunct to diet and exercise for adults with…”
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Sustained Remission and Outcomes with Abatacept plus Methotrexate Following Stepwise Dose De-escalation in Patients with Early Rheumatoid Arthritis by Emery, Paul, Tanaka, Yoshiya, Bykerk, Vivian P., Huizinga, Thomas W. J., Citera, Gustavo, Bingham, Clifton O., Banerjee, Subhashis, Soule, Benjamin P., Nys, Marleen, Connolly, Sean E., Lozenski, Karissa L., Zhuo, Joe, Wong, Robert, Huang, Kuan-Hsiang Gary, Fleischmann, Roy

“…Introduction One target of rheumatoid arthritis (RA) treatment is to achieve early sustained remission; over the long term, patients in sustained remission…”
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Assessment of tissue redox status using metabolic responsive contrast agents and magnetic resonance imaging by Hyodo, Fuminori, Soule, Benjamin P., Matsumoto, Ken-ichiro, Matusmoto, Shingo, Cook, John A., Hyodo, Emi, Sowers, Anastasia L., Krishna, Murali C., Mitchell, James B.

“…Regulation of tissue redox status is important to maintain normal physiological conditions in the living body. Disruption of redox homoeostasis may lead to…”
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Suspected Non-Infectious Prosthetic Valve Inflammatory Dehiscence In X-Linked Chronic Granulomatous Disease by Bhagat, Monica, Dr, Steinberg, Joshua A., Dr, Silvestry, Frank, Dr, Surrey, Lea, Dr, Apter, Andrea J., Dr, Takach, Patricia A., Dr, Soule, Benjamin P., Dr

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Intrarectal Amifostine During External Beam Radiation Therapy for Prostate Cancer Produces Significant Improvements in Quality of Life Measured by EPIC Score by Simone, Nicole L., M.D, Ménard, Cynthia, M.D, Soule, Benjamin P., M.D, Albert, Paul S., Ph.D, Guion, Peter, M.S, Smith, Sharon, R.N, Godette, Denise, C.C.P.R, Crouse, Nancy S., R.N, Sciuto, Linda C., R.N, Cooley-Zgela, Theresa, R.N, Camphausen, Kevin, M.D, Coleman, C. Norman, M.D, Singh, Anurag K., M.D

“…Purpose To test whether intrarectal amifostine limits symptoms of radiation proctitis, measured by using the Radiation Therapy Oncology Group (RTOG)…”
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Residual NADPH Oxidase and Survival in Chronic Granulomatous Disease by Kuhns, Douglas B, Alvord, W. Gregory, Heller, Theo, Feld, Jordan J, Pike, Kristen M, Marciano, Beatriz E, Uzel, Gulbu, DeRavin, Suk See, Priel, Debra A. Long, Soule, Benjamin P, Zarember, Kol A, Malech, Harry L, Holland, Steven M, Gallin, John I

“…Survival in chronic granulomatous disease is related to the level of NADPH oxidase activity, which correlates with the altered site on the mutated gene…”
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Loratadine dysregulates cell cycle progression and enhances the effect of radiation in human tumor cell lines by Soule, Benjamin P, Simone, Nicole L, DeGraff, William G, Choudhuri, Rajani, Cook, John A, Mitchell, James B

“…The histamine receptor-1 (H1)-antagonist, loratadine has been shown to inhibit growth of human colon cancer xenografts in part due to cell cycle arrest in…”
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776-P: Comparative Effectiveness of SC Semaglutide in Adults with T2D in U.S. Routine Clinical Practice—Year 1 Results of SEPRA, a Randomized Pragmatic Clinical Trial by BUSE, JOHN B., SOULE, BENJAMIN P., HARTY, BRIAN J., CHRISTENSEN, HELENE N., CZIRAKY, MARK J., WILLEY, VINCENT, SKIBSTED, SIMON

“…SEPRA, a 2-year, ongoing, open-label, randomized, pragmatic study (NCT03596450) compares the effects of once-weekly SC semaglutide (sema) with physician's…”
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752-P: Study Design and Baseline Profile for Patients with Type 2 Diabetes in the Semaglutide Once-Weekly Randomized Pragmatic Trial (SEPRA) by WILLEY, VINCENT, BUSE, JOHN B., HARTY, BRIAN, MITCHELL, JULIE L., SOULE, BENJAMIN P., CHRISTENSEN, HELENE N., CZIRAKY, MARK J., SKIBSTED, SIMON

“…SEPRA (NCT03596450) is a 2-yr, multicenter, open-label, randomized pragmatic clinical trial comparing the long-term effects of once-weekly subcutaneous…”
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The chemistry and biology of nitroxide compounds by Soule, Benjamin P., Hyodo, Fuminori, Matsumoto, Ken-ichiro, Simone, Nicole L., Cook, John A., Krishna, Murali C., Mitchell, James B.

“…Cyclic nitroxides are a diverse group of stable free radicals that have unique antioxidant properties. Because of their ability to interact with free radicals,…”
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MicroRNA expression altered by diet: Can food be medicinal? by Palmer, Joshua D, Soule, Benjamin P, Simone, Brittany A, Zaorsky, Nicholas G, Jin, Lianjin, Simone, Nicole L

“…Highlights • microRNA's affected by diet are reviewed. • microRNA families most dysregulated are discussed. • The same families role in disease is illustrated…”
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Oral pirfenidone in patients with chronic fibrosis resulting from radiotherapy: a pilot study by Simone, Nicole L, Soule, Benjamin P, Gerber, Lynn, Augustine, Elizabeth, Smith, Sharon, Altemus, Rosemary M, Mitchell, James B, Camphausen, Kevin A

“…Fibrosis is a common side effect after treatment with ionizing radiation. Several methods to ameliorate debilitating fibrosis have been employed but without…”
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Assessment of Atherosclerosis in Chronic Granulomatous Disease by Sibley, Christopher T, Estwick, Tyra, Zavodni, Anna, Huang, Chiung-Yu, Kwan, Alan C, Soule, Benjamin P, Long Priel, Debra A, Remaley, Alan T, Rudman Spergel, Amanda K, Turkbey, Evrim B, Kuhns, Douglas B, Holland, Steven M, Malech, Harry L, Zarember, Kol A, Bluemke, David A, Gallin, John I

“…BACKGROUND—Patients with chronic granulomatous disease (CGD) experience immunodeficiency because of defects in the phagocyte NADPH oxidase and the concomitant…”
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Safety of Abatacept Versus Placebo in Rheumatoid Arthritis: Integrated Data Analysis of Nine Clinical Trials by Simon, Teresa A., Soule, Benjamin P., Hochberg, Marc, Fleming, Douglas, Torbeyns, Anne, Banerjee, Subhashis, Boers, Maarten

“…Objective To assess the safety of abatacept treatment in rheumatoid arthritis (RA) using integrated data from multiple clinical trials. Methods Data from nine…”
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Correction: Cellular Stress Induced Alterations in MicroRNA let-7a and let-7b Expression Are Dependent on p53 by Saleh, Anthony D, Savage, Jason E, Cao, Liu, Soule, Benjamin P, Ly, David, DeGraff, William, Harris, Curtis C, Mitchell, James B, Simone, Nicole L

“…A note linking to a correct version of the article can be found on the article page. (2012) Correction: Cellular Stress Induced Alterations in MicroRNA let-7a…”
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Food Allergy Testing in Adult Eosinophilic Esophagitis, Clarifying the Role of the Allergist by Ray, Manujendra, MD, PhD, Soule, Benjamin P., MD

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Residual NADPH Oxidase and Survival in Chronic Granulomatous Disease by KUHNS, Douglas B, ALVORD, W. Gregory, ZAREMBER, Kol A, MALECH, Harry L, HOLLAND, Steven M, GALLIN, John I, HELLER, Theo, FELD, Jordan J, PIKE, Kristen M, MARCIANO, Beatriz E, UZEL, Gulbu, SUK SEE DERAVIN, LONG, Debra A, SOULE, Benjamin P

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