Search Results - "SORICE, GIAN PIO"
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Removal of Duodenum Elicits GLP-1 Secretion
Published in Diabetes care (01-06-2013)“…To evaluate the effect of removal of the duodenum on the complex interplay between incretins, insulin, and glucagon in nondiabetic subjects. For evaluation of…”
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2
Sotagliflozin, the first dual SGLT inhibitor: current outlook and perspectives
Published in Cardiovascular diabetology (28-02-2019)“…Sotagliflozin is a dual sodium-glucose co-transporter-2 and 1 (SGLT2/1) inhibitor for the treatment of both type 1 (T1D) and type 2 diabetes (T2D)…”
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3
Glucagon in type 2 diabetes: Friend or foe?
Published in Diabetes/metabolism research and reviews (01-03-2023)“…Hyperglucagonemia is one of the ‘ominous’ eight factors underlying the pathogenesis of type 2 diabetes (T2D). Glucagon is a peptide hormone involved in…”
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981-P: Transition from Standard Time to Daylight Saving Time and Vice Versa—Effects on FGM Metrics in Patients with Autoimmune Diabetes
Published in Diabetes (New York, N.Y.) (20-06-2023)“…Circadian rhythm variations, including transition from standard time (ST) to daylight saving time (DST), are associated with measurable effects on health. It…”
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Adipose Tissue Inflammation and Pulmonary Dysfunction in Obesity
Published in International journal of molecular sciences (01-07-2022)“…Obesity is a chronic disease caused by an excess of adipose tissue that may impair health by altering the functionality of various organs, including the lungs…”
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6
Insulin Resistance Alters Islet Morphology in Nondiabetic Humans
Published in Diabetes (New York, N.Y.) (01-03-2014)“…Type 2 diabetes is characterized by poor glucose uptake in metabolic tissues and manifests when insulin secretion fails to cope with worsening insulin…”
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Cardiovascular and Renal Effectiveness of GLP-1 Receptor Agonists vs. Other Glucose-Lowering Drugs in Type 2 Diabetes: A Systematic Review and Meta-Analysis of Real-World Studies
Published in Metabolites (15-02-2022)“…Cardiovascular outcome trials (CVOT) showed that treatment with glucagon-like peptide-1 receptor agonists (GLP-1RA) is associated with significant…”
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Diet and Proteinuria: State of Art
Published in International journal of molecular sciences (20-12-2022)“…Proteinuria is a broad term used to describe the pathological presence of proteins, including albumin, globulin, Bence-Jones protein, and mucoprotein in the…”
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Dapagliflozin improves myocardial flow reserve in patients with type 2 diabetes: the DAPAHEART Trial: a preliminary report
Published in Cardiovascular diabetology (03-09-2022)“…Abstract Objective Cardiovascular (CV) outcome trials have shown that in patients with type 2 diabetes (T2D), treatment with sodium-glucose cotransporter-2…”
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Efficacy and Safety of Different Hybrid Closed Loop Systems for Automated Insulin Delivery in People With Type 1 Diabetes: A Systematic Review and Network Meta‐Analysis
Published in Diabetes/metabolism research and reviews (01-09-2024)“…ABSTRACT Aims To compare the efficacy and safety of different hybrid closed loop (HCL) systems in people with diabetes through a network meta‐analysis. Methods…”
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HCC development is associated to peripheral insulin resistance in a mouse model of NASH
Published in PloS one (22-05-2014)“…NAFLD is the most common liver disease worldwide but it is the potential evolution to NASH and eventually to hepatocellular carcinoma (HCC), even in the…”
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12
Medical therapy of aortic aneurysms: a pathophysiology-based approach
Published in Current vascular pharmacology (01-09-2011)“…One of the critical points in the pathogenesis of aortic aneurysms (AAs) is the disruption of the balance between vascular extracellular matrix (ECM)…”
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13
Incretin-based therapies for the treatment of obesity-related diseases
Published in npj metabolic health and disease (06-11-2024)“…Obesity-related disability-adjusted life years (DALYs) are expected to increase by approximately 40% from 2020 to 2030. DALYs and mortality related to obesity…”
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14
The Interplay between Immune System and Microbiota in Diabetes
Published in Mediators of inflammation (2019)“…Diabetes is not a single and homogeneous disease, but a cluster of metabolic diseases characterized by the common feature of hyperglycemia. The pathogenesis of…”
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Dapagliflozin treatment is associated with a reduction of epicardial adipose tissue thickness and epicardial glucose uptake in human type 2 diabetes
Published in Cardiovascular diabetology (19-12-2023)“…We recently demonstrated that treatment with sodium-glucose cotransporter-2 inhibitors (SGLT-2i) leads to an increase in myocardial flow reserve in patients…”
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Mini Review: Effect of GLP-1 Receptor Agonists and SGLT-2 Inhibitors on the Growth Hormone/IGF Axis
Published in Frontiers in endocrinology (Lausanne) (21-02-2022)“…Accumulating evidence supports the early use of glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium glucose transporter-2 inhibitors (SGLT-2is) for…”
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Spotlight on ertugliflozin and its potential in the treatment of type 2 diabetes: evidence to date
Published in Drug design, development and therapy (01-01-2017)“…Sodium-glucose cotransporter 2 (SGLT2) inhibitors are the latest therapeutic strategy in the treatment of type 2 diabetes mellitus (T2DM). Using an…”
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Bile Modulates Secretion of Incretins and Insulin: A Study of Human Extrahepatic Cholestasis
Published in The journal of clinical endocrinology and metabolism (01-07-2019)“…Abstract Objective Changes in bile flow after bariatric surgery may beneficially modulate secretion of insulin and incretins, leading to diabetes remission…”
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The size of adrenal incidentalomas correlates with insulin resistance. Is there a cause-effect relationship?
Published in Clinical endocrinology (Oxford) (01-03-2011)“…Summary Context Adrenal incidentalomas (AI) have often been associated with a high prevalence of insulin resistance (IR) and cardiovascular risk factors,…”
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Metabolic consequences of the occlusion of the main pancreatic duct with acrylic glue after pancreaticoduodenectomy
Published in The American journal of surgery (01-10-2015)“…Abstract Background Pancreaticoduodenectomy represents the major treatment for pancreatic and periampullary neoplasms. Complications related to…”
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