Search Results - "SORIANO, J. V"
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Hepatocyte growth factor stimulates extensive development of branching duct-like structures by cloned mammary gland epithelial cells
Published in Journal of cell science (01-02-1995)“…Although epithelial-mesenchymal (stromal) interactions are thought to play an important role in embryonic and postnatal development of the mammary gland, the…”
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Isolation of Eph4 Mammary Epithelial Cell Subpopulations Which Differ in Their Morphogenetic Properties
Published in In vitro cellular & developmental biology. Animal (01-06-1998)“…EpH4 is a nontumorigenic cell line derived from spontaneously immortalized mouse mammary gland epithelial cells (Fialka et al., 1996). When grown in collagen…”
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Modulation of clusterin gene expression in the rat mammary gland during pregnancy, lactation, and involution
Published in Biology of reproduction (01-12-1996)“…The mammary gland provides an excellent system for investigating factors involved in the regulation of epithelial growth, differentiation, morphogenesis, and…”
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Induction of tissue inhibitor of metalloproteinases-3 is a delayed early cellular response to hepatocyte growth factor
Published in Oncogene (30-07-1998)“…Hepatocyte growth factor (HGF) stimulates mitogenic, motogenic, and morphogenic responses in various cell types. We analysed HGF-responsive cells by…”
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Expression of an activated Notch4(int‐3) oncoprotein disrupts morphogenesis and induces an invasive phenotype in mammary epithelial cells in vitro
Published in International journal of cancer (01-06-2000)“…The protein encoded by the Notch4 gene is a member of the Notch/lin‐12 family of transmembrane receptor proteins, which have been shown to control cell fate…”
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Repression of the putative tumor suppressor gene Bard1 or expression of Notch4(int-3) oncogene subvert the morphogenetic properties of mammary epithelial cells
Published in Advances in experimental medicine and biology (2000)“…We have investigated whether repression of the putative tumor suppressor gene BARD1 or expression of the Notch4(int-3) oncogene in non-tumorigenic mammary…”
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Heterogeneity and contact-dependent regulation of amylase release by individual acinar cells
Published in Journal of cellular physiology (01-08-1994)“…We have used a reverse hemolytic plaque assay to investigate the amylase release of single and aggregated pancreatic acinar cells. We have found that a…”
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Identification of BARD1 as Mediator between Proapoptotic Stress and p53-Dependent Apoptosis
Published in Molecular cell (01-12-2001)“…The BRCA1-associated protein BARD1 is a putative tumor suppressor. We suggest that BARD1 is a mediator of apoptosis since (1) cell death in vivo (ischemic…”
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Potent Blockade of Hepatocyte Growth Factor-stimulated Cell Motility, Matrix Invasion and Branching Morphogenesis by Antagonists of Grb2 Src Homology 2 Domain Interactions
Published in The Journal of biological chemistry (27-04-2001)“…Hepatocyte growth factor (HGF) stimulates mitogenesis, motogenesis, and morphogenesis in a wide range of cellular targets during development, homeostasis and…”
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Notch4 and Wnt-1 Proteins Function to Regulate Branching Morphogenesis of Mammary Epithelial Cells in an Opposing Fashion
Published in Developmental biology (15-04-1998)“…Elongation and branching of epithelial ducts is a crucial event during the development of the mammary gland. Branching morphogenesis of the mouse mammary…”
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In vitro Repression of Brca1-Associated RING Domain Gene, Bard1, Induces Phenotypic Changes in Mammary Epithelial Cells
Published in The Journal of cell biology (30-11-1998)“…BRCA1-associated RING domain (BARD1) was identified as a protein interacting with the breast cancer gene product BRCA1. The identification of tumorigenic…”
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Regulation of VEGF and VEGF receptor expression in the rodent mammary gland during pregnancy, lactation, and involution
Published in Developmental dynamics (01-07-2000)“…Vascular endothelial growth factors (VEGFs) are endothelial cell‐specific mitogens with potent angiogenic and vascular permeability‐inducing properties. VEGF,…”
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Constitutively active mitogen-activated protein kinase kinase MEK1 disrupts morphogenesis and induces an invasive phenotype in Madin-Darby canine kidney epithelial cells
Published in Cell growth & differentiation (01-05-1999)“…During certain developmental processes, as well as during tumor progression, polarized epithelial cells integrated within multicellular structures convert into…”
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Induction of epithelial branching tubulogenesis in vitro
Published in Journal of cellular physiology (01-11-1997)Get full text
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Modulation of Hepatocyte Growth Factor and c-met in the Rat Mammary Gland during Pregnancy, Lactation, and Involution
Published in Experimental cell research (01-07-1995)“…Epithelial tubulegenesis is responsible for the exquisitely intricate organization of functional units of parenchymal organs. We have previously demonstrated…”
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Differential effects of hepatocyte growth factor isoforms on epithelial and endothelial tubulogenesis
Published in Cell growth & differentiation (01-05-1998)“…Hepatocyte growth factor (HGF)/scatter factor (SF) is a pleiotropic cytokine that acts as a mitogen, motogen, and morphogen for a variety of cell types…”
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Chromogranin A Alters Ductal Morphogenesis and Increases Deposition of Basement Membrane Components by Mammary Epithelial Cells in Vitro
Published in Biochemical and biophysical research communications (16-06-1999)“…The extracellular function of chromogranin A (CgA), a glycoprotein widely distributed in secretory vesicles of neurons and neuroendocrine cells, has not been…”
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External RNA Controls Consortium: a progress report
Published in Nature methods (01-10-2005)“…Standard controls and best practice guidelines advance acceptance of data from research, preclinical and clinical laboratories by providing a means for…”
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TGF-β1Induces Morphogenesis of Branching Cords by Cloned Mammary Epithelial Cells at Subpicomolar Concentrations
Published in Biochemical and biophysical research communications (27-03-1996)Get full text
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TGF-beta1 induces morphogenesis of branching cords by cloned mammary epithelial cells at subpicomolar concentrations
Published in Biochemical and biophysical research communications (27-03-1996)“…The factors which control the formation of lactiferous ducts during mammary gland development are not yet fully understood. To address this issue, we assessed…”
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