Search Results - "SORENSON, Martha M."

Myosin is reversibly inhibited by S-nitrosylation by Nogueira, Leonardo, Figueiredo-Freitas, Cicero, Casimiro-Lopes, Gustavo, Magdesian, Margaret H, Assreuy, Jamil, Sorenson, Martha M

“…Nitric oxide (NO*) is synthesized in skeletal muscle and its production increases during contractile activity. Although myosin is the most abundant protein in…”
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Amide hydrogens reveal a temperature-dependent structural transition that enhances site-II Ca2+-binding affinity in a C-domain mutant of cardiac troponin C by Veltri, Tiago, de Oliveira, Guilherme A. P., Bienkiewicz, Ewa A., Palhano, Fernando L., Marques, Mayra de A., Moraes, Adolfo H., Silva, Jerson L., Sorenson, Martha M., Pinto, Jose R.

“…The hypertrophic cardiomyopathy-associated mutant D145E, in cardiac troponin C (cTnC) C-domain, causes generalised instability at multiple sites in the…”
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Betaine protects urea-induced denaturation of myosin subfragment-1 by Ortiz-Costa, Susana, Sorenson, Martha M, Sola-Penna, Mauro

“…We have demonstrated previously that urea inhibits the activity and alters the tertiary structure of skeletal muscle myosin in a biphasic manner. This was…”
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The impact of stem cells on electron fluxes, proton translocation, and ATP synthesis in kidney mitochondria after ischemia/reperfusion by Beiral, Hellen J V, Rodrigues-Ferreira, Clara, Fernandes, Aline M, Gonsalez, Sabrina R, Mortari, Nicoli C, Takiya, Christina M, Sorenson, Martha M, Figueiredo-Freitas, Cícero, Galina, Antonio, Vieyra, Adalberto

“…Tissue damage by ischemia/reperfusion (I/R) results from a temporary cessation of blood flow followed by the restoration of circulation. The injury depresses…”
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Brazilian Science and Research Integrity: Where are We? What Next? by Vasconcelos, Sonia M R, Sorenson, Martha M, Watanabe, Edson H, Foguel, Debora, Palácios, Marisa

“…Building a world-class scientific community requires first-class ingredients at many different levels: funding, training, management, international…”
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Modulation of troponin C affinity for the thin filament by different cross-bridge states in skinned skeletal muscle fibers by Pinto, José Renato, Veltri, Tiago, Sorenson, Martha M.

“…In vertebrate skeletal muscle, the C-domain of troponin C (TnC) serves as an anchor; the N-domain regulates the position of troponin–tropomyosin on the thin…”
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2,4-Dinitrophenol reduces the reactivity of Lys553 in the lower 50-kDa region of myosin subfragment 1 by Bomfim, Theresa R., Machado, Luciana E.S.F., Lima, Luis Mauricio T.R., Sorenson, Martha M., Salerno, Verônica P.

“…► The compound 2,4-dinitrophenol (DNP) binds near a helix-loop-helix that includes a reactive lysine (Lys553) in myosin’s lower 50-kDa subdomain, activating…”
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S-Nitrosylation of Sarcomeric Proteins Depresses Myofilament Ca2+)Sensitivity in Intact Cardiomyocytes by Figueiredo-Freitas, Cícero, Dulce, Raul A, Foster, Matthew W, Liang, Jingsheng, Yamashita, Aline M S, Lima-Rosa, Frederico L, Thompson, J Will, Moseley, M Arthur, Hare, Joshua M, Nogueira, Leonardo, Sorenson, Martha M, Pinto, José Renato

“…The heart responds to physiological and pathophysiological stress factors by increasing its production of nitric oxide (NO), which reacts with intracellular…”
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Balance between S -nitrosylation and denitrosylation modulates myoblast proliferation independently of soluble guanylyl cyclase activation by Yamashita, Aline M S, Ancillotti, Maryana T C, Rangel, Luciana P, Fontenele, Marcio, Figueiredo-Freitas, Cicero, Possidonio, Ana C, Soares, Carolina P, Sorenson, Martha M, Mermelstein, Claudia, Nogueira, Leonardo

“…Nitric oxide (NO) contributes to myogenesis by regulating the transition between myoblast proliferation and fusion through cGMP signaling. NO can form…”
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Allosteric Transmission along a Loosely Structured Backbone Allows a Cardiac Troponin C Mutant to Function with Only One Ca2+ Ion by Marques, Mayra de A., Pinto, Jose Renato, Moraes, Adolfo H., Iqbal, Anwar, de Magalhães, Mariana T.Q., Monteiro, Jamila, Pedrote, Murilo M., Sorenson, Martha M., Silva, Jerson L., de Oliveira, Guilherme A.P.

“…Hypertrophic cardiomyopathy (HCM) is one of the most common cardiomyopathies and a major cause of sudden death in young athletes. The Ca2+ sensor of the…”
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Discussing plagiarism in Latin American science: Brazilian researchers begin to address an ethical issue by Vasconcelos, Sonia, Leta, Jacqueline, Costa, Lídia, Pinto, André, Sorenson, Martha M

“…Most developed countries have extensive guidelines about research integrity, which reflects a global attempt to harmonize policies for handling research…”
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Exogenous β-amyloid peptide interferes with GLUT4 localization in neurons by Oliveira, Leandro T, Leon, Gabbriela V.O, Provance, D. William, de Mello, Fernando G, Sorenson, Martha M, Salerno, Verônica P

“…Abstract Aging represents a major risk factor for numerous illnesses that are of increasing importance to society, including two of the most prevalent:…”
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Redox state of Troponin C Cysteine in the D/E helix alters the C-domain affinity for the thin filament of vertebrate striated muscle by Pinto, José Renato, de Sousa, Valeria Pereira, Sorenson, Martha M

“…BACKGROUND: Despite a broad spectrum of structural studies, it is not yet clear whether the D/E helix of troponin C (TnC) contributes to the interaction of TnC…”
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Strong Cross-bridges Potentiate the Ca²⁺ Affinity Changes Produced by Hypertrophic Cardiomyopathy Cardiac Troponin C Mutants in Myofilaments: A FAST KINETIC APPROACH by Pinto, Jose Renato, Reynaldo, Daniel P, Parvatiyar, Michelle S, Dweck, David, Liang, Jingsheng, Jones, Michelle A, Sorenson, Martha M, Potter, James D

“…This spectroscopic study examined the steady-state and kinetic parameters governing the cross-bridge effect on the increased Ca²⁺ affinity of hypertrophic…”
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Strong cross-bridges potentiate the Ca(2+) affinity changes produced by hypertrophic cardiomyopathy cardiac troponin C mutants in myofilaments: a fast kinetic approach by Pinto, Jose Renato, Reynaldo, Daniel P, Parvatiyar, Michelle S, Dweck, David, Liang, Jingsheng, Jones, Michelle A, Sorenson, Martha M, Potter, James D

“…This spectroscopic study examined the steady-state and kinetic parameters governing the cross-bridge effect on the increased Ca(2+) affinity of hypertrophic…”
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The new geography of scientific collaborations: Changing patterns in the geography of science pose ethical challenges for collaborations between established and emerging scientific powers by Vasconcelos, Sonia M R, Steneck, Nicholas H, Anderson, Melissa, Masuda, Hatisaburo, Palacios, Marisa, Pinto, José C S, Sorenson, Martha M

“…The science ethics melting pot is just heating up; what role will emerging nations play in setting new standards of practice that ensure successful…”
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Researchers' writing competence: a bottleneck in the publication of Latin-American science? by Vasconcelos, Sonia M.R., Sorenson, Martha M., Leta, Jacqueline, Sant'Ana, Maurício C., Batista, Pablo D.

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Redox balance and mitochondrial glycerol phosphate dehydrogenase activity in trained rats by Casimiro-Lopes, Gustavo, Ramos, Dionizio, Sorenson, Martha M., Salerno, Verônica P.

“…Free radical production is increased in many disease states and during exercise, but in the latter the concurrent stimulation of the antioxidant defense system…”
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Insights into the Intramolecular Coupling between the N- and C‑Domains of Troponin C Derived from High-Pressure, Fluorescence, Nuclear Magnetic Resonance, and Small-Angle X‑ray Scattering Studies by de Oliveira, Guilherme A. P, Rocha, Cristiane B, Marques, Mayra de A, Cordeiro, Yraima, Sorenson, Martha M, Foguel, Débora, Silva, Jerson L, Suarez, Marisa C

“…Troponin C (TnC), the Ca2+-binding component of the troponin complex of vertebrate skeletal muscle, consists of two structurally homologous domains, the N- and…”
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Chemical treatment of mica for atomic force microscopy can affect biological sample conformation by Costa, Lilian T., Pinto, José R., Moraes, Marta B., de Souza, Guttierre G.B., Sorenson, Martha M., Bisch, Paulo M., Weissmüller, Gilberto

“…An important aspect in the preparation of substrate materials to use in atomic force microscopy lies in the question of interactions introduced by treatments…”
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